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2XMQ
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Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
Descriptor: ACETATE ION, PROTEIN NDRG2
Authors:Hwang, J, Kim, Y, Lee, H, Kim, M.H.
Deposit date:2010-07-29
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
3DVT
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BU of 3dvt by Molmil
Biochemical and structural characterization of the PAK1- LC8 interaction
Descriptor: Dynein light chain 1, cytoplasmic
Authors:LIghtcap, C.M, Williams, J.C.
Deposit date:2008-07-20
Release date:2009-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVH
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LC8 Point mutant K36P
Descriptor: Dynein light chain 1, cytoplasmic
Authors:Lightcap, C.M, Williams, J.C.
Deposit date:2008-07-18
Release date:2009-01-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVP
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BU of 3dvp by Molmil
Pak1 peptide bound LC8
Descriptor: Dynein light chain 1, cytoplasmic, P21 activated Kinase peptide
Authors:Lightcap, C.M, Williams, J.C.
Deposit date:2008-07-18
Release date:2009-01-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3B13
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BU of 3b13 by Molmil
Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant)
Descriptor: Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1
Authors:Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
Deposit date:2011-06-24
Release date:2012-03-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.006 Å)
Cite:Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
4JMO
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Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JQ0
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BU of 4jq0 by Molmil
Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin
Descriptor: CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ...
Authors:Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S.
Deposit date:2013-03-19
Release date:2014-05-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.84 Å)
Cite:Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.
Nat Commun, 5, 2014
4MX9
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CDPK1 from Neospora caninum in complex with inhibitor UW1294
Descriptor: 3-(6-ethoxynaphthalen-2-yl)-1-[(1-methylpiperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-like domain protein kinase isoenzyme gamma, related
Authors:Merritt, E.A.
Deposit date:2013-09-26
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
2OD8
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BU of 2od8 by Molmil
Structure of a peptide derived from Cdc9 bound to PCNA
Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
Authors:Chapados, B.R, Tainer, J.A.
Deposit date:2006-12-21
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
1L7Z
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BU of 1l7z by Molmil
Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide
Descriptor: CALCIUM ION, CALMODULIN, CAP-23/NAP-22, ...
Authors:Matsubara, M, Nakatsu, T, Yamauchi, E, Kato, H, Taniguchi, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-03-18
Release date:2003-09-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulin
EMBO J., 23, 2004
5ZB3
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BU of 5zb3 by Molmil
Dimeric crystal structure of ORF57 from KSHV
Descriptor: ORF57, ZINC ION
Authors:Gao, Z.Q, Yuan, F, Dong, Y.H, Lan, K.
Deposit date:2018-02-09
Release date:2018-08-08
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function.
PLoS Pathog., 14, 2018
4NAM
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BU of 4nam by Molmil
1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y)
Descriptor: CALCIUM ION, Protective antigen
Authors:Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G.
Deposit date:2013-10-22
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:(19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability.
Biochemistry, 53, 2014
3C6L
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BU of 3c6l by Molmil
Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20
Descriptor: 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain), CALCIUM ION, ...
Authors:Dai, S.
Deposit date:2008-02-04
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
3C1Q
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BU of 3c1q by Molmil
The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ...
Authors:Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J.
Deposit date:2008-01-24
Release date:2009-02-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
4N0H
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Crystal structure of S. cerevisiae mitochondrial GatFAB
Descriptor: Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glutamyl-tRNA(Gln) amidotransferase subunit B, ...
Authors:Araiso, Y, Ishitani, R, Nureki, O.
Deposit date:2013-10-02
Release date:2014-04-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases
Nucleic Acids Res., 42, 2014
3C2X
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BU of 3c2x by Molmil
Crystal structure of peptidoglycan recognition protein at 1.8A resolution
Descriptor: GLYCEROL, L(+)-TARTARIC ACID, Peptidoglycan recognition protein, ...
Authors:Sharma, P, Singh, N, Sinha, M, Sharma, S, Perbandt, M, Betzel, C, Kaur, P, Srinivasan, A, Singh, T.P.
Deposit date:2008-01-26
Release date:2008-03-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the peptidoglycan recognition protein at 1.8 A resolution reveals dual strategy to combat infection through two independent functional homodimers
J.Mol.Biol., 378, 2008
3HTS
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BU of 3hts by Molmil
HEAT SHOCK TRANSCRIPTION FACTOR/DNA COMPLEX
Descriptor: 5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3', GLYCEROL, HEAT SHOCK TRANSCRIPTION FACTOR
Authors:Littlefield, O, Nelson, H.C.M.
Deposit date:1998-11-16
Release date:1999-04-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal.
Nat.Struct.Biol., 6, 1999
3C5Z
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BU of 3c5z by Molmil
Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506
Descriptor: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain), ...
Authors:Dai, S, Kappler, J.
Deposit date:2008-02-01
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
2PVS
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BU of 2pvs by Molmil
Structure of human pancreatic lipase related protein 2 mutant N336Q
Descriptor: CALCIUM ION, Pancreatic lipase-related protein 2, SULFATE ION
Authors:Spinelli, S, Eydoux, C, Carriere, F, Cambillau, C.
Deposit date:2007-05-10
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
4N8W
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BU of 4n8w by Molmil
cathepsin K - chondroitin sulfate complex
Descriptor: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Cathepsin K
Authors:Aguda, A.H, Nguyen, N.T, Bromme, D, Brayer, G.D.
Deposit date:2013-10-18
Release date:2014-11-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis of collagen fiber degradation by cathepsin K.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JUY
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BU of 3juy by Molmil
Crystal Structure of a 3B3 Variant, a Broadly Neutralizing HIV-1 scFv Antibody
Descriptor: 3B3 single chain variant HIV-1 antibody
Authors:Clark, K.R, Walsh, S.T.
Deposit date:2009-09-15
Release date:2009-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a 3B3 variant-A broadly neutralizing HIV-1 scFv antibody.
Protein Sci., 18, 2009
3G6W
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BU of 3g6w by Molmil
Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kadziola, A, Christoffersen, S.
Deposit date:2009-02-09
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
J.Mol.Biol., 393, 2009
4JXH
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Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-28
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
2PHO
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BU of 2pho by Molmil
Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution
Descriptor: Arginase-1, HYDRAZINECARBOTHIOAMIDE, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2007-04-11
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
1LJW
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BU of 1ljw by Molmil
Crystal Structure of Human Carbonmonoxy Hemoglobin at 2.16 A: A Snapshot of the Allosteric Transition
Descriptor: CARBON MONOXIDE, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Safo, M.K, Burnett, J.C, Musayev, F.N, Nokuri, S, Abraham, D.J.
Deposit date:2002-04-22
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structure of human carbonmonoxyhemoglobin at 2.16 A: a snapshot of the allosteric transition.
Acta Crystallogr.,Sect.D, 58, 2002

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数据于2024-07-17公开中

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