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7NLG
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BU of 7nlg by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant A273V mutant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.528 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
6XK4
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BU of 6xk4 by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(((3-(6-aminopyridin-2-yl)propyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-{[3-({[4-(6-aminopyridin-2-yl)butyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, GLYCEROL, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
6XK8
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BU of 6xk8 by Molmil
Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-((((6-aminopyridin-2-yl)methyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-{[3-({[(6-aminopyridin-2-yl)methyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
7NPF
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BU of 7npf by Molmil
Vibrio cholerae ParA2-ATPyS-DNA filament
Descriptor: AAA family ATPase, DNA (49-MER), MAGNESIUM ION, ...
Authors:Parker, A.V, Bergeron, J.R.C.
Deposit date:2021-02-26
Release date:2021-10-06
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding.
Nat Commun, 12, 2021
7NLH
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BU of 7nlh by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG1 variant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
6XK3
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BU of 6xk3 by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(((pyridin-2-ylmethyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-{[3-({[(pyridin-2-yl)methyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
6XK7
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BU of 6xk7 by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(2-(6-aminopyridin-2-yl)ethyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine, CHLORIDE ION, GLYCEROL, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
6XK6
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BU of 6xk6 by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(((2-(pyridin-2-yl)ethyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-{[3-({[2-(pyridin-2-yl)ethyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, GLYCEROL, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
6XK5
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BU of 6xk5 by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(((4-(6-aminopyridin-2-yl)butyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-{[3-({[3-(6-aminopyridin-2-yl)propyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, GLYCEROL, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
6XN8
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BU of 6xn8 by Molmil
Crystal Structure of 2-hydroxyacyl CoA lyase (HACL) from Rhodospirillales bacterium URHD0017
Descriptor: 2-hydroxyacyl-CoA lyase 1, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Miller, M.D, Xu, W, Olmos Jr, J.L, Chou, A, Clomburg, J.M, Gonzalez, R, Philips Jr, G.N.
Deposit date:2020-07-02
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of 2-hydroxyacyl CoA lyase (HACL) from Rhodospirillales bacterium URHD0017
To Be Published
6XMC
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BU of 6xmc by Molmil
Nitric Oxide Synthase from Bacillus subtilis in complex with 7-((3-(2-(6-aminopyridin-2-yl)ethyl)phenoxy)methyl)quinolin-2-amine
Descriptor: 7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine, CHLORIDE ION, GLYCEROL, ...
Authors:Lewis, M.C, Poulos, T.L.
Deposit date:2020-06-30
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase
To Be Published
2B1X
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BU of 2b1x by Molmil
Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Gakhar, L, Malik, Z.A, Allen, C.C, Lipscomb, D.A, Larkin, M.J, Ramaswamy, S.
Deposit date:2005-09-16
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase.
J.Bacteriol., 187, 2005
6XC9
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BU of 6xc9 by Molmil
Immune receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Tresoldi, M.C.E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
Deposit date:2020-06-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
2IC3
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BU of 2ic3 by Molmil
Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with Nonnucleoside Inhibitor HBY 097
Descriptor: (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H (p51 RT), ...
Authors:Das, K, Arnold, E.
Deposit date:2006-09-12
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structures of Clinically Relevant Lys103Asn/Tyr181Cys Double Mutant HIV-1 Reverse Transcriptase in Complexes with ATP and Non-nucleoside Inhibitor HBY 097.
J.Mol.Biol., 365, 2007
2B53
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BU of 2b53 by Molmil
Human cyclin dependent kinase 2 (CDK2) complexed with DIN-234325
Descriptor: 6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE, Cell division protein kinase 2
Authors:Muckelbauer, J.
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Quinazolines as Cyclin Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 11, 2001
2B7F
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BU of 2b7f by Molmil
Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design
Descriptor: (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION
Authors:Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A.
Deposit date:2005-10-04
Release date:2005-12-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design
Proc.Natl.Acad.Sci.Usa, 102, 2005
2BBL
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BU of 2bbl by Molmil
NMR structures of the peptide linked to the genome (VPg) of poliovirus in a stabilizing solvent
Descriptor: Genome linked protein VPg
Authors:Schein, C.H, Oezguen, N.
Deposit date:2005-10-17
Release date:2006-03-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the viral peptide linked to the genome (VPg) of poliovirus.
Peptides, 27, 2006
2BBP
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BU of 2bbp by Molmil
NMR structures of the peptide linked to the genome (VPg) of poliovirus
Descriptor: Genome linked protein VPg
Authors:Schein, C.H, Oezguen, N.
Deposit date:2005-10-17
Release date:2006-03-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the viral peptide linked to the genome (VPg) of poliovirus.
Peptides, 27, 2006
2BCG
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BU of 2bcg by Molmil
Structure of doubly prenylated Ypt1:GDI complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERAN-8-YL GERAN, GTP-binding protein YPT1, ...
Authors:Pylypenko, O, Rak, A, Alexandrov, K.
Deposit date:2005-10-19
Release date:2006-01-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling
Embo J., 25, 2006
7N4Y
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BU of 7n4y by Molmil
The structure of bovine thyroglobulin with iodinated tyrosines
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kim, K, Clarke, O.B.
Deposit date:2021-06-04
Release date:2021-11-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:The structure of natively iodinated bovine thyroglobulin.
Acta Crystallogr D Struct Biol, 77, 2021
2B55
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BU of 2b55 by Molmil
Human cyclin dependent kinase 2 (cdk2) complexed with indenopyraxole DIN-101312
Descriptor: 2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE, Cell division protein kinase 2
Authors:Muckelbauer, J.
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3
J.Med.Chem., 45, 2002
2B9C
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BU of 2b9c by Molmil
Structure of tropomyosin's mid-region: bending and binding sites for actin
Descriptor: striated-muscle alpha tropomyosin
Authors:Brown, J.H, Zhou, Z, Reshetnikova, L, Robinson, H, Yammani, R.D, Tobacman, L.S, Cohen, C.
Deposit date:2005-10-11
Release date:2006-01-03
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the mid-region of tropomyosin: Bending and binding sites for actin.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2IDU
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BU of 2idu by Molmil
Structure of M98Q mutant of amicyanin, Cu(I)
Descriptor: Amicyanin, COPPER (I) ION
Authors:Carrell, C.J, Ma, J.K, Antholine, W, Hosler, J.P, Mathews, F.S, Davidson, V.L.
Deposit date:2006-09-15
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Generation of Novel Copper Sites by Mutation of the Axial Ligand of Amicyanin. Atomic Resolution Structures and Spectroscopic Properties
Biochemistry, 46, 2007
2B4G
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BU of 2b4g by Molmil
dihydroorotate dehydrogenase
Descriptor: BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-23
Release date:2005-10-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
Mol.Microbiol., 68, 2008
2B54
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BU of 2b54 by Molmil
Human cyclin dependent kinase 2 (CKD2)complexed with DIN-232305
Descriptor: 6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE, Cell division protein kinase 2
Authors:Chang, C.-C.
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1h-pyraxolo[3,4-d]pyrimidin-4-one inhibitors of cyclin dependent kinases
J.Med.Chem., 47, 2004

223790

数据于2024-08-14公开中

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