6XK8

Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-((((6-aminopyridin-2-yl)methyl)amino)methyl)phenoxy)methyl)quinolin-2-amine

Summary for 6XK8

• Entry DOI: 10.2210/pdb6xk8/pdb
• Descriptor: Nitric oxide synthase oxygenase, PROTOPORPHYRIN IX CONTAINING FE, 7-{[3-({[(6-aminopyridin-2-yl)methyl]amino}methyl)phenoxy]methyl}quinolin-2-amine, ... (8 entities in total)
• Functional Keywords: inhibitor, nitric oxide synthase, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Bacillus subtilis (strain 168)
• Total number of polymer chains: 1
• Total formula weight: 43266.98

Authors

Lewis, M.C.,Poulos, T.L. (deposition date: 2020-06-25, release date: 2021-06-30, Last modification date: 2023-10-18)

• Primary citation: Lewis, M.C.,Poulos, T.L.; Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)