4F0Y
 
 | | Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-IG from Acinetobacter haemolyticus, apo | | Descriptor: | Aminoglycoside N(6')-acetyltransferase type 1, CHLORIDE ION, GLYCEROL, ... | | Authors: | Stogios, P.J, Evdokimova, E, Dong, A, Minasov, G, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-05-05 | | Release date: | 2012-05-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
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1PLW
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150L
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5D4A
 | | Crystal Structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl)propanoic acid | | Descriptor: | 3-(2-phenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte | | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | | Deposit date: | 2015-08-07 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis
Acs Med.Chem.Lett., 7, 2016
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1PIS
 | | SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 | | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | | Authors: | Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. | | Deposit date: | 1994-12-22 | | Release date: | 1995-06-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of porcine pancreatic phospholipase A2.
EMBO J., 14, 1995
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1PIR
 | | SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 | | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | | Authors: | Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. | | Deposit date: | 1994-12-22 | | Release date: | 1995-06-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of porcine pancreatic phospholipase A2.
EMBO J., 14, 1995
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2C9G
 | | THE QUASI-ATOMIC MODEL OF THE ADENOVIRUS TYPE 3 PENTON BASE DODECAHEDRON | | Descriptor: | PENTON PROTEIN | | Authors: | Fuschiotti, P, Schoehn, G, Fender, P, Fabry, C.M.S, Hewat, E.A, Chroboczek, J, Ruigrok, R.W.H, Conway, J.F. | | Deposit date: | 2005-12-12 | | Release date: | 2006-01-04 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Structure of the Dodecahedral Penton Particle from Human Adenovirus Type 3.
J.Mol.Biol., 356, 2006
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3G43
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3GE7
 | | tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one | | Descriptor: | 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | | Authors: | Ritschel, T, Heine, A, Klebe, G. | | Deposit date: | 2009-02-25 | | Release date: | 2009-12-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase
Chemmedchem, 4, 2009
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5DBL
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5CT2
 | | The structure of the NK1 fragment of HGF/SF complexed with CAPS | | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Hepatocyte growth factor | | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | | Deposit date: | 2015-07-23 | | Release date: | 2015-08-12 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.
Chem Sci, 6, 2015
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4BW7
 | | Calmodulin in complex with strontium | | Descriptor: | CALMODULIN, STRONTIUM ION | | Authors: | Kursula, P. | | Deposit date: | 2013-06-30 | | Release date: | 2014-01-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Crystallographic Snapshots of Initial Steps in the Collapse of the Calmodulin Central Helix
Acta Crystallogr.,Sect.D, 70, 2014
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5D45
 | | Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid | | Descriptor: | 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid, Fatty acid-binding protein, adipocyte | | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | | Deposit date: | 2015-08-07 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis
Acs Med.Chem.Lett., 7, 2016
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1ZEH
 | | STRUCTURE OF INSULIN | | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | Deposit date: | 1998-05-01 | | Release date: | 1998-12-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
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3DJ8
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5CS3
 | | The structure of the NK1 fragment of HGF/SF complexed with (H)EPPS | | Descriptor: | 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, Hepatocyte growth factor | | Authors: | Sigurdardottir, A.G, Winter, A, Sobkowicz, A, Fragai, M, Chirgadze, D.Y, Ascher, D.B, Blundell, T.L, Gherardi, E. | | Deposit date: | 2015-07-23 | | Release date: | 2015-08-12 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.
Chem Sci, 6, 2015
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1Y6W
 | | Trapped intermediate of calmodulin | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Calmodulin, ... | | Authors: | Grabarek, Z. | | Deposit date: | 2004-12-07 | | Release date: | 2005-03-01 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of a Trapped Intermediate of Calmodulin: Calcium Regulation of EF-hand Proteins from a New Perspective.
J.Mol.Biol., 346, 2005
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3R68
 | | Molecular Analysis of the PDZ3 domain of PDZK1 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Kocher, O, Birrane, G, Krieger, M. | | Deposit date: | 2011-03-21 | | Release date: | 2011-05-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011
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5D47
 | | Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl] propanoic acid | | Descriptor: | 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl]propanoic acid, Fatty acid-binding protein, adipocyte | | Authors: | Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T. | | Deposit date: | 2015-08-07 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis
Acs Med.Chem.Lett., 7, 2016
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3BV4
 | | Crystal structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant | | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase A, SULFATE ION | | Authors: | Sherawat, M, Tolan, D.R, Allen, K.N. | | Deposit date: | 2008-01-04 | | Release date: | 2008-06-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant.
Acta Crystallogr.,Sect.D, 64, 2008
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3BYA
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4DJS
 | | Structure of beta-catenin in complex with a stapled peptide inhibitor | | Descriptor: | Catenin beta-1, stapled peptide RRWPQ(MK8)ILD(MK8)HVRRVWR | | Authors: | Bowman, B.R, Grossmann, T.N, Yeh, J.T.-H, Verdine, G.L. | | Deposit date: | 2012-02-02 | | Release date: | 2012-10-17 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (3.029 Å) | | Cite: | Inhibition of oncogenic Wnt signaling through direct targeting of beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5T8L
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1XFV
 | | Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP | | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin 2, ... | | Authors: | Shen, Q, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | | Deposit date: | 2004-09-15 | | Release date: | 2005-05-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
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2EI4
 | | Trimeric complex of archaerhodopsin-2 | | Descriptor: | 2,3-DI-PHYTANYL-GLYCEROL, Archaerhodopsin-2, BACTERIORUBERIN, ... | | Authors: | Kouyama, T. | | Deposit date: | 2007-03-11 | | Release date: | 2008-01-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-2
J.Mol.Biol., 375, 2008
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