1FUA
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![BU of 1fua by Molmil](/molmil-images/mine/1fua) | L-FUCULOSE 1-PHOSPHATE ALDOLASE CRYSTAL FORM T | Descriptor: | BETA-MERCAPTOETHANOL, L-FUCULOSE-1-PHOSPHATE ALDOLASE, SULFATE ION, ... | Authors: | Dreyer, M.K, Schulz, G.E. | Deposit date: | 1996-02-14 | Release date: | 1996-10-14 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Refined high-resolution structure of the metal-ion dependent L-fuculose-1-phosphate aldolase (class II) from Escherichia coli. Acta Crystallogr.,Sect.D, 52, 1996
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2OJK
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![BU of 2ojk by Molmil](/molmil-images/mine/2ojk) | Crystal Structure of Green Fluorescent Protein from Zoanthus sp at 2.2 A Resolution | Descriptor: | GFP-like fluorescent chromoprotein FP506 | Authors: | Pletneva, N.V, Pletnev, S.V, Tikhonova, T.V, Pletnev, V.Z. | Deposit date: | 2007-01-12 | Release date: | 2007-09-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Refined crystal structures of red and green fluorescent proteins from the button polyp Zoanthus. Acta Crystallogr.,Sect.D, 63, 2007
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6U6Z
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![BU of 6u6z by Molmil](/molmil-images/mine/6u6z) | Human SAMHD1 bound to deoxyribo(TG*TTCA)-oligonucleotide | Descriptor: | DNA polymer TG(PST)TCA, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | Authors: | Taylor, A.B, Yu, C.H, Ivanov, D.N. | Deposit date: | 2019-08-30 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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6ZN2
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![BU of 6zn2 by Molmil](/molmil-images/mine/6zn2) | Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding. | Descriptor: | FE (III) ION, L-DOPAMINE, SER-LEU-ILE-GLU-ASP-ALA-ARG-LYS-GLU-ARG-GLU-ALA-ALA-VAL-ALA-ALA-ALA-ALA, ... | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-07-06 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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2I2X
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![BU of 2i2x by Molmil](/molmil-images/mine/2i2x) | Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri | Descriptor: | 5-HYDROXYBENZIMIDAZOLYLCOB(III)AMIDE, Methyltransferase 1, POTASSIUM ION, ... | Authors: | Hagemeier, C.H, Kruer, M, Thauer, R.K, Warkentin, E, Ermler, U. | Deposit date: | 2006-08-17 | Release date: | 2006-11-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex Proc.Natl.Acad.Sci.Usa, 103, 2006
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4RMO
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![BU of 4rmo by Molmil](/molmil-images/mine/4rmo) | Crystal Structure of the CptIN Type III Toxin-Antitoxin System from Eubacterium rectale | Descriptor: | CALCIUM ION, CptN Toxin, RNA (45-MER) | Authors: | Rao, F, Voss, J.E, Short, F.L, Luisi, B.F. | Deposit date: | 2014-10-21 | Release date: | 2015-09-30 | Last modified: | 2015-11-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system. Nucleic Acids Res., 43, 2015
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5EPO
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![BU of 5epo by Molmil](/molmil-images/mine/5epo) | The three-dimensional structure of Clostridium absonum 7alpha-hydroxysteroid dehydrogenase | Descriptor: | 7-alpha-hydroxysteroid deydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lou, D, Wang, B, Wang, F. | Deposit date: | 2015-11-12 | Release date: | 2016-03-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The three-dimensional structure of Clostridium absonum 7 alpha-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition Sci Rep, 6, 2016
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4RXY
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![BU of 4rxy by Molmil](/molmil-images/mine/4rxy) | |
6IST
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![BU of 6ist by Molmil](/molmil-images/mine/6ist) | Crystal structure of a wild type endolysin LysIME-EF1 | Descriptor: | CALCIUM ION, Lysin | Authors: | Ouyang, S.Y. | Deposit date: | 2018-11-19 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage. Plos Pathog., 16, 2020
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4TQP
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![BU of 4tqp by Molmil](/molmil-images/mine/4tqp) | Human transthyretin (TTR) complexed with (R)-3-(9H-fluoren-9-ylideneaminooxy)-2-methyl-N-(methylsulfonyl) propionamide in a dual binding mode | Descriptor: | (2R)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methyl-N-(methylsulfonyl)propanamide, GLYCEROL, Transthyretin | Authors: | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | Deposit date: | 2014-06-11 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors. J Enzyme Inhib Med Chem, 2015
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6UBN
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![BU of 6ubn by Molmil](/molmil-images/mine/6ubn) | Crystal structure of D678E GoxA bound to glycine | Descriptor: | MAGNESIUM ION, Quinoprotein glycine oxidase, SODIUM ION | Authors: | Yukl, E.T. | Deposit date: | 2019-09-12 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Kinetic and structural evidence that Asp-678 plays multiple roles in catalysis by the quinoprotein glycine oxidase. J.Biol.Chem., 294, 2019
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4TU1
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![BU of 4tu1 by Molmil](/molmil-images/mine/4tu1) | Structure of Toxoplasma gondii fructose 1,6 bisphosphate aldolase | Descriptor: | Fructose-1,6-bisphosphate aldolase, GLYCEROL | Authors: | Boucher, L.E, Bosch, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2014-06-23 | Release date: | 2014-09-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase. Acta Crystallogr.,Sect.F, 70, 2014
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6TXW
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![BU of 6txw by Molmil](/molmil-images/mine/6txw) | V30G Transthyretin structure in complex with Tolcalpone | Descriptor: | Tolcapone, Transthyretin | Authors: | Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. | Deposit date: | 2020-01-14 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.153 Å) | Cite: | Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis. Febs J., 288, 2021
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4TQH
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![BU of 4tqh by Molmil](/molmil-images/mine/4tqh) | Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid | Descriptor: | 1,2-ETHANEDIOL, Transthyretin, [(9H-fluoren-9-ylideneamino)oxy]acetic acid | Authors: | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | Deposit date: | 2014-06-11 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.511 Å) | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors. J Enzyme Inhib Med Chem, 2015
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7ANZ
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![BU of 7anz by Molmil](/molmil-images/mine/7anz) | Structure of the Candida albicans gamma-Tubulin Small Complex | Descriptor: | Spindle pole body component, Tubulin gamma chain | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2020-10-13 | Release date: | 2020-11-04 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The cryo-EM structure of a gamma-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems. Nat Commun, 11, 2020
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6K1N
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![BU of 6k1n by Molmil](/molmil-images/mine/6k1n) | PLP-bound form of a putative cystathionine gamma-lyase | Descriptor: | Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Chen, S, Wang, Y. | Deposit date: | 2019-05-10 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis. Int.J.Biol.Macromol., 174, 2021
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6KBN
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![BU of 6kbn by Molmil](/molmil-images/mine/6kbn) | Crystal structure of Vac8 (del 19-33) bound to Atg13 | Descriptor: | Autophagy-related protein 13, Vacuolar protein 8 | Authors: | Park, J, Lee, C. | Deposit date: | 2019-06-25 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. Autophagy, 16, 2020
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5E9T
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![BU of 5e9t by Molmil](/molmil-images/mine/5e9t) | Crystal structure of GtfA/B complex | Descriptor: | Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, MAGNESIUM ION | Authors: | Chen, Y, Rapoport, T.A. | Deposit date: | 2015-10-15 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EKP
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![BU of 5ekp by Molmil](/molmil-images/mine/5ekp) | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (WT) | Descriptor: | MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 | Authors: | Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2015-11-03 | Release date: | 2016-01-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.194 Å) | Cite: | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
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7AL2
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![BU of 7al2 by Molmil](/molmil-images/mine/7al2) | |
6UFQ
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![BU of 6ufq by Molmil](/molmil-images/mine/6ufq) | Crystal structure of D678N GoxA bound to glycine | Descriptor: | GLYCINE, Glycine Oxidase GoxA, MAGNESIUM ION | Authors: | Yukl, E.T. | Deposit date: | 2019-09-24 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Kinetic and structural evidence that Asp-678 plays multiple roles in catalysis by the quinoprotein glycine oxidase. J.Biol.Chem., 294, 2019
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6TXV
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![BU of 6txv by Molmil](/molmil-images/mine/6txv) | A25T Transthyretin structure in complex with Tolcalpone | Descriptor: | Tolcapone, Transthyretin | Authors: | Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. | Deposit date: | 2020-01-14 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis. Febs J., 288, 2021
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1T5A
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![BU of 1t5a by Molmil](/molmil-images/mine/1t5a) | Human Pyruvate Kinase M2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... | Authors: | Dombrauckas, J.D, Santarsiero, B.D, Mesecar, A.D. | Deposit date: | 2004-05-03 | Release date: | 2005-07-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. Biochemistry, 44, 2005
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4TQ8
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![BU of 4tq8 by Molmil](/molmil-images/mine/4tq8) | Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR) | Descriptor: | 1,2-ETHANEDIOL, 3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid, Transthyretin | Authors: | Ciccone, L, Orlandini, E, Nencetti, S, Rossello, A, Stura, E.A. | Deposit date: | 2014-06-10 | Release date: | 2015-06-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors. J Enzyme Inhib Med Chem, 2015
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6UBZ
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![BU of 6ubz by Molmil](/molmil-images/mine/6ubz) | Crystal structure of D678A GoxA bound to glycine at pH 5.5 | Descriptor: | GLYCINE, MAGNESIUM ION, Uncharacterized protein GoxA | Authors: | Yukl, E.T. | Deposit date: | 2019-09-13 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Kinetic and structural evidence that Asp-678 plays multiple roles in catalysis by the quinoprotein glycine oxidase. J.Biol.Chem., 294, 2019
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