1T5A

Human Pyruvate Kinase M2

Summary for 1T5A

Entry DOI	10.2210/pdb1t5a/pdb
Descriptor	Pyruvate kinase, M2 isozyme, 1,6-di-O-phosphono-beta-D-fructofuranose, OXALATE ION, ... (8 entities in total)
Functional Keywords	alpha8-beta8 barrel, beta sheets, alpha helices, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	252701.23
Authors	Dombrauckas, J.D.,Santarsiero, B.D.,Mesecar, A.D. (deposition date: 2004-05-03, release date: 2005-07-12, Last modification date: 2023-09-20)
Primary citation	Dombrauckas, J.D.,Santarsiero, B.D.,Mesecar, A.D. Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. Biochemistry, 44:9417-9429, 2005 Cited by PubMed: 15996096 DOI: 10.1021/bi0474923 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation