1T5A
Human Pyruvate Kinase M2
Summary for 1T5A
Entry DOI | 10.2210/pdb1t5a/pdb |
Descriptor | Pyruvate kinase, M2 isozyme, 1,6-di-O-phosphono-beta-D-fructofuranose, OXALATE ION, ... (8 entities in total) |
Functional Keywords | alpha8-beta8 barrel, beta sheets, alpha helices, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 252701.23 |
Authors | Dombrauckas, J.D.,Santarsiero, B.D.,Mesecar, A.D. (deposition date: 2004-05-03, release date: 2005-07-12, Last modification date: 2023-09-20) |
Primary citation | Dombrauckas, J.D.,Santarsiero, B.D.,Mesecar, A.D. Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. Biochemistry, 44:9417-9429, 2005 Cited by PubMed: 15996096DOI: 10.1021/bi0474923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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