1T5A
Human Pyruvate Kinase M2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase, M2 isozyme | polymer | 567 | 62128.3 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (human) | |
| 2 | E, IA, O, X (A, D, B, C) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 3 | F, JA, P, Y (A, D, B, C) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 4 | G, KA, Q, Z (A, D, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 5 | AA, H, LA, R (C, A, D, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | BA, I, MA, S (C, A, D, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 7 | CA, DA, EA, FA, GA... (C, A, D, B) | GLYCEROL | non-polymer | 92.1 | 20 | Chemie (GOL) | |||
| 8 | SA, TA, UA, VA (A, B, C, D) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 531 (UniProt: P14618)
| PDB | External Database | Details |
|---|---|---|
| Met -35 | - | cloning artifact |
| Arg -34 | - | cloning artifact |
| Gly -33 | - | cloning artifact |
| Ser -32 | - | cloning artifact |
| His -31 | - | cloning artifact |
| His -30 | - | cloning artifact |
| His -29 | - | cloning artifact |
| His -28 | - | cloning artifact |
| His -27 | - | cloning artifact |
| His -26 | - | cloning artifact |
| Gly -25 | - | cloning artifact |
| Met -24 | - | cloning artifact |
| Ala -23 | - | cloning artifact |
| Ser -22 | - | cloning artifact |
| Met -21 | - | cloning artifact |
| Thr -20 | - | cloning artifact |
| Gly -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Gln -17 | - | cloning artifact |
| Gln -16 | - | cloning artifact |
| Met -15 | - | cloning artifact |
| Gly -14 | - | cloning artifact |
| Arg -13 | - | cloning artifact |
| Asp -12 | - | cloning artifact |
| Leu -11 | - | cloning artifact |
| Tyr -10 | - | cloning artifact |
| Asp -9 | - | cloning artifact |
| Asp -8 | - | cloning artifact |
| Asp -7 | - | cloning artifact |
| Asp -6 | - | cloning artifact |
| Lys -5 | - | cloning artifact |
| Asp -4 | - | cloning artifact |
| His -3 | - | cloning artifact |
| Pro -2 | - | cloning artifact |
| Phe -1 | - | cloning artifact |
| Thr 0 | - | cloning artifact |
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 248513.3 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 4187.9 | |
| All* | Total formula weight | 252701.2 |
