Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7ZMR
DownloadVisualize
BU of 7zmr by Molmil
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2*-011
Descriptor: ATP-dependent DNA helicase Q5, Gluebody G2*-011, SULFATE ION, ...
Authors:Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F.
Deposit date:2022-04-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts
To Be Published
6XHS
DownloadVisualize
BU of 6xhs by Molmil
Crystal structure of S. aureus TarI in complex with CTP (space group P1211)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribitol-5-phosphate cytidylyltransferase 1, ...
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2020-06-19
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
6I69
DownloadVisualize
BU of 6i69 by Molmil
Circular permutant of ribosomal protein S6, adding 5aa to C terminal of P97-3, L10A mutant
Descriptor: 30S ribosomal protein S6
Authors:Wang, H, Logan, D.T, Oliveberg, M.
Deposit date:2018-11-15
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
7PF7
DownloadVisualize
BU of 7pf7 by Molmil
Apo structure of SynFtn variant D65A
Descriptor: CHLORIDE ION, Ferritin, SODIUM ION
Authors:Hemmings, A.M, Bradley, J.M.
Deposit date:2021-08-11
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Key carboxylate residues for iron transit through the prokaryotic ferritin Syn Ftn.
Microbiology (Reading, Engl.), 167, 2021
6BCN
DownloadVisualize
BU of 6bcn by Molmil
I-LtrI E184D bound to cognate substrate (pre-cleavage complex)
Descriptor: CALCIUM ION, DNA (26-MER), Ribosomal protein 3/homing endonuclease-like fusion protein
Authors:Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res., 46, 2018
7ZLE
DownloadVisualize
BU of 7zle by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
Deposit date:2022-04-14
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published
5TIJ
DownloadVisualize
BU of 5tij by Molmil
Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer)
Descriptor: ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION
Authors:Leonard, P.G, Muller, F.L.
Deposit date:2016-10-03
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Eradication of ENO1-deleted Glioblastoma through Collateral Lethality
Biorxiv, 2019
6XHR
DownloadVisualize
BU of 6xhr by Molmil
Crystal structure of S. aureus TarI (space group P1211)
Descriptor: Ribitol-5-phosphate cytidylyltransferase 1, THIOCYANATE ION
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2020-06-19
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
5TH7
DownloadVisualize
BU of 5th7 by Molmil
Complex of SETD8 with MS453
Descriptor: 1,2-ETHANEDIOL, N-(3-{[6,7-dimethoxy-2-(pyrrolidin-1-yl)quinazolin-4-yl]amino}propyl)propanamide, N-lysine methyltransferase KMT5A, ...
Authors:Yu, W, Tempel, W, Babault, N, Ma, A, Butler, K.V, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-29
Release date:2016-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase.
J. Med. Chem., 59, 2016
7ZMQ
DownloadVisualize
BU of 7zmq by Molmil
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2*-006
Descriptor: ATP-dependent DNA helicase Q5, Gluebody G2*-006, SULFATE ION, ...
Authors:Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F.
Deposit date:2022-04-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts
To Be Published
6E6X
DownloadVisualize
BU of 6e6x by Molmil
The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 1-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxy-2-methylpyridin-4(1H)-one
Descriptor: 1,2-ETHANEDIOL, 5-hydroxy-2-methyl-1-[4-(1H-tetrazol-5-yl)phenyl]pyridin-4(1H)-one, MANGANESE (II) ION, ...
Authors:Dick, B.L, Morrison, C.N, Credille, C.V, Cohen, S.M.
Deposit date:2018-07-25
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease.
J.Med.Chem., 62, 2019
6XHT
DownloadVisualize
BU of 6xht by Molmil
Crystal structure of S. aureus TarI in complex with CDP-ribitol (space group P1211)
Descriptor: CDP-ribitol, Ribitol-5-phosphate cytidylyltransferase 1, THIOCYANATE ION
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2020-06-19
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J.Struct.Biol., 213, 2021
6PCB
DownloadVisualize
BU of 6pcb by Molmil
Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex with COA
Descriptor: Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, COENZYME A, ...
Authors:Sukritee, B, Panjikar, S.
Deposit date:2019-06-17
Release date:2020-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
6PBI
DownloadVisualize
BU of 6pbi by Molmil
Crystal Structure of EcDsbA in a complex with purified morpholine 8
Descriptor: 2-methyl-4-{4-[2-(morpholin-4-yl)-2-oxoethyl]phenoxy}benzonitrile, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
Authors:Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J.
Deposit date:2019-06-13
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ).
J.Med.Chem., 63, 2020
5THA
DownloadVisualize
BU of 5tha by Molmil
Gemin5 WD40 repeats in complex with a guanosyl moiety
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, Gem-associated protein 5, UNKNOWN ATOM OR ION
Authors:Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-29
Release date:2016-10-19
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
7PRP
DownloadVisualize
BU of 7prp by Molmil
Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in apo form
Descriptor: FORMIC ACID, Heat-labile enterotoxin IIA, B chain, ...
Authors:Varrot, A.
Deposit date:2021-09-22
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.
Glycobiology, 32, 2022
6ART
DownloadVisualize
BU of 6art by Molmil
Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with cesium ions
Descriptor: Acetyl-CoA acetyltransferase, CESIUM ION, CHLORIDE ION, ...
Authors:Marshall, A.C, Bond, C.S, Bruning, J.B.
Deposit date:2017-08-23
Release date:2018-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations
Acs Catalysis, 8(3), 2018
7ZML
DownloadVisualize
BU of 7zml by Molmil
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001
Descriptor: ATP-dependent DNA helicase Q5, Gluebody G1-001, SULFATE ION, ...
Authors:Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F.
Deposit date:2022-04-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts
To Be Published
7ZHI
DownloadVisualize
BU of 7zhi by Molmil
Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor indole
Descriptor: Aspartate carbamoyltransferase, INDOLE, SULFATE ION
Authors:Wang, C, Zhang, B.
Deposit date:2022-04-06
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.946 Å)
Cite:Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
6E8N
DownloadVisualize
BU of 6e8n by Molmil
Crystal structure of glycosylated human EPDR1
Descriptor: Mammalian ependymin-related protein 1, NONAETHYLENE GLYCOL
Authors:Wei, Y, Prive, G.G.
Deposit date:2018-07-30
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Commun Biol, 2, 2019
7ZLU
DownloadVisualize
BU of 7zlu by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-2-deoxy-2-fluoro-D-glucose
Descriptor: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Ibba, R.
Deposit date:2022-04-15
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
6PED
DownloadVisualize
BU of 6ped by Molmil
Crystal structure of HEMK2-TRMT112 complex
Descriptor: Methyltransferase N6AMT1, Multifunctional methyltransferase subunit TRM112-like protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2019-06-20
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of HEMK2-TRMT112 complex
To Be Published
6E8Y
DownloadVisualize
BU of 6e8y by Molmil
Unliganded Human Glycerol 3-Phosphate Dehydrogenase
Descriptor: 2,2-bis(hydroxymethyl)propane-1,3-diol, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic, ...
Authors:Mydy, L.S, Gulick, A.M.
Deposit date:2018-07-31
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies.
Biochemistry, 58, 2019
6AT9
DownloadVisualize
BU of 6at9 by Molmil
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101
Descriptor: ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
Deposit date:2017-08-28
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9503 Å)
Cite:A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
5THT
DownloadVisualize
BU of 5tht by Molmil
Crystal Structure of G303A HDAC8 in complex with M344
Descriptor: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2016-09-30
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.407 Å)
Cite:Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016

224201

数据于2024-08-28公开中

PDB statisticsPDBj update infoContact PDBjnumon