8R4I
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8CMQ
| Crystal structure of an 8-repeat consensus TPR superhelix with Tb | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ... | Authors: | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | Deposit date: | 2023-02-20 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8OWJ
| Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OVM
| Lipidic amyloid-beta(1-40) fibril - polymorph L2 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-26 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWE
| Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-27 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OVK
| Lipidic amyloid-beta(1-40) fibril - polymorph L1 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-26 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWK
| Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWD
| Lipidic amyloid-beta(1-40) fibril - polymorph L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-27 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8CKR
| Crystal structure of an 8-repeat consensus TPR superhelix with in Hepes with Ca | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Consensus tetratricopeptide repeat protein | Authors: | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | Deposit date: | 2023-02-16 | Release date: | 2024-02-28 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CHY
| Crystal structure of an 8-repeat consensus TPR superhelix with Zinc. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | Deposit date: | 2023-02-08 | Release date: | 2024-02-21 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CH0
| Crystal structure of an 8-repeat consensus TPR superhelix with Gadolinium. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ... | Authors: | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | Deposit date: | 2023-02-06 | Release date: | 2024-02-21 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CIG
| Crystal structure of an 8-repeat consensus TPR superhelix in tris Buffer with Calcium. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | Deposit date: | 2023-02-09 | Release date: | 2024-02-21 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8F5Y
| Crystal structure of pregnane X receptor ligand binding domain complexed with JQ1 | Descriptor: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, Nuclear receptor coactivator 1, Nuclear receptor subfamily 1 group I member 2 | Authors: | Huber, A.D, Poudel, S, Seetharaman, J, Miller, D.J, Chen, T. | Deposit date: | 2022-11-15 | Release date: | 2024-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR. Nucleic Acids Res., 52, 2024
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7FU4
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-fluoro-4-phenylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | Descriptor: | (8S)-2-{[(3-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | Authors: | Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. | Deposit date: | 2023-02-08 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.926 Å) | Cite: | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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8OHI
| Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OH2
| Structure of the Tau-PAM4 Type 1 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-20 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OHP
| Structure of the Fmoc-Tau-PAM4 Type 3 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OI0
| Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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7FU5
| Crystal Structure of human cyclic GMP-AMP synthase | Descriptor: | (8S)-2-{[(3-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, SULFATE ION, ... | Authors: | Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. | Deposit date: | 2023-02-08 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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8OPB
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8OT4
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8X36
| Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP, IPP, and magnesium ion (form B) | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. | Deposit date: | 2023-11-12 | Release date: | 2024-02-07 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
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8X35
| Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP, IPP, and magnesium ion (form A) | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. | Deposit date: | 2023-11-12 | Release date: | 2024-02-07 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
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8X37
| Neryl diphosphate synthase from Solanum lycopersicum complexed with DMSAPP | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, Neryl-diphosphate synthase 1 | Authors: | Imaizumi, R, Matsuura, H, Yanai, T, Takeshita, K, Misawa, S, Yamaguchi, H, Sakai, N, Miyagi-Inoue, Y, Suenaga-Hiromori, M, Kataoka, K, Nakayama, T, Yamamoto, M, Takahashi, S, Yamashita, S. | Deposit date: | 2023-11-12 | Release date: | 2024-02-07 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural-Functional Correlations between Unique N-terminal Region and C-terminal Conserved Motif in Short-chain cis-Prenyltransferase from Tomato. Chembiochem, 25, 2024
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8OT1
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