7FU4

Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-fluoro-4-phenylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

Summary for 7FU4

• Entry DOI: 10.2210/pdb7fu4/pdb
• Group deposition: To be published (G_1002263)
• Descriptor: Cyclic GMP-AMP synthase, ZINC ION, (8S)-2-{[(3-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, ... (4 entities in total)
• Functional Keywords: immune response, transferase, ntase, dna sensor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42847.73

Authors

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Hunziker, D.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21)

• Primary citation: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.926 Å)