1EJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ejy by Molmil](/molmil-images/mine/1ejy) | |
6MJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mjl by Molmil](/molmil-images/mine/6mjl) | Crystal structure of ChREBP NLS peptide bound to importin alpha. | Descriptor: | ChREBP Peptide ASN-TYR-TRP-LYS-ARG-ARG-ILE-GLU-VAL, Importin subunit alpha-1 | Authors: | Jung, H, Uyeda, K. | Deposit date: | 2018-09-21 | Release date: | 2019-09-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of importin alpha and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin alpha interactions. Biochem.J., 477, 2020
|
|
3NMX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nmx by Molmil](/molmil-images/mine/3nmx) | Crystal structure of APC complexed with Asef | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | Deposit date: | 2010-06-22 | Release date: | 2011-07-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
|
|
1F59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f59 by Molmil](/molmil-images/mine/1f59) | IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX | Descriptor: | FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1 | Authors: | Bayliss, R, Littlewood, T, Stewart, M. | Deposit date: | 2000-06-13 | Release date: | 2000-08-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell(Cambridge,Mass.), 102, 2000
|
|
6N88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n88 by Molmil](/molmil-images/mine/6n88) | |
1M5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m5n by Molmil](/molmil-images/mine/1m5n) | Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP | Descriptor: | Importin beta-1 subunit, Parathyroid hormone-related protein | Authors: | Cingolani, G, Bednenko, J, Gillespie, M.T, Gerace, L. | Deposit date: | 2002-07-09 | Release date: | 2003-01-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular basis for the recognition
of a nonclassical nuclear localization
signal by importin beta Mol.Cell, 10, 2002
|
|
5H2X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h2x by Molmil](/molmil-images/mine/5h2x) | |
5GXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gxw by Molmil](/molmil-images/mine/5gxw) | Importin and NuMA complex | Descriptor: | Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1 | Authors: | Chang, C.-C, Huang, T.-L, Hsia, K.-C. | Deposit date: | 2016-09-20 | Release date: | 2017-10-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Regulation of mitotic spindle assembly factor NuMA by Importin-beta J. Cell Biol., 216, 2017
|
|
5H2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h2w by Molmil](/molmil-images/mine/5h2w) | |
1O6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o6o by Molmil](/molmil-images/mine/1o6o) | |
5HUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5huy by Molmil](/molmil-images/mine/5huy) | |
1M1E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m1e by Molmil](/molmil-images/mine/1m1e) | Beta-catenin armadillo repeat domain bound to ICAT | Descriptor: | Beta-catenin, ICAT | Authors: | Daniels, D.L, Weis, W.I. | Deposit date: | 2002-06-18 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | ICAT inhibits Beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Mol.Cell, 10, 2002
|
|
5HUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5huw by Molmil](/molmil-images/mine/5huw) | |
5HHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hhg by Molmil](/molmil-images/mine/5hhg) | Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex | Descriptor: | Importin subunit alpha-1, RNA-directed RNA polymerase NS5 | Authors: | Smith, K.M, Forwood, J.K. | Deposit date: | 2016-01-11 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
|
|
5FC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fc8 by Molmil](/molmil-images/mine/5fc8) | Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex | Descriptor: | Importin subunit alpha-1, Nonstructural protein 5 | Authors: | Smith, K.M, Forwood, J.K. | Deposit date: | 2015-12-15 | Release date: | 2016-05-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
|
|
5H43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h43 by Molmil](/molmil-images/mine/5h43) | |
5IZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iz8 by Molmil](/molmil-images/mine/5iz8) | Protein-protein interaction | Descriptor: | ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein, TRIETHYLENE GLYCOL | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | Deposit date: | 2016-03-25 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
|
|
1LUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1luj by Molmil](/molmil-images/mine/1luj) | Crystal Structure of the Beta-catenin/ICAT Complex | Descriptor: | Beta-catenin-interacting protein 1, Catenin beta-1 | Authors: | Graham, T.A, Clements, W.K, Kimelman, D, Xu, W. | Deposit date: | 2002-05-22 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol.Cell, 10, 2002
|
|
1PJN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pjn by Molmil](/molmil-images/mine/1pjn) | Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex | Descriptor: | Histone-binding protein N1/N2, Importin alpha-2 subunit | Authors: | Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. | Deposit date: | 2003-06-03 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
|
|
1PJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pjm by Molmil](/molmil-images/mine/1pjm) | Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex | Descriptor: | Importin alpha-2 subunit, Retinoblastoma-associated protein | Authors: | Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. | Deposit date: | 2003-06-03 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
|
|
1O6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o6p by Molmil](/molmil-images/mine/1o6p) | |
1Q1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q1s by Molmil](/molmil-images/mine/1q1s) | Mouse Importin alpha- phosphorylated SV40 CN peptide complex | Descriptor: | Importin alpha-2 subunit, Large T antigen | Authors: | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | Deposit date: | 2003-07-22 | Release date: | 2004-03-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
|
|
1Q1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q1t by Molmil](/molmil-images/mine/1q1t) | Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex | Descriptor: | Importin alpha-2 subunit, Large T antigen | Authors: | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | Deposit date: | 2003-07-22 | Release date: | 2004-03-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
|
|
7L04
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l04 by Molmil](/molmil-images/mine/7l04) | |
7LF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lf4 by Molmil](/molmil-images/mine/7lf4) | |