5V0I
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![BU of 5v0i by Molmil](/molmil-images/mine/5v0i) | Crystal Structure of Tryptophanyl-tRNA Synthetase from Escherichia coli Complexed with AMP and Tryptophan | Descriptor: | ADENOSINE MONOPHOSPHATE, FORMIC ACID, TRYPTOPHAN, ... | Authors: | Maltseva, N, Kim, Y, Mulligan, R, Grimshaw, S.G, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-28 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Tryptophanyl-tRNA Synthetase from Escherichia coli Complexed with AMP and Tryptophan To Be Published
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4GS5
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![BU of 4gs5 by Molmil](/molmil-images/mine/4gs5) | The crystal structure of acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein from Dyadobacter fermentans DSM 18053 | Descriptor: | 1,2-ETHANEDIOL, Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein, IODIDE ION | Authors: | Tan, K, Holowicki, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-08-27 | Release date: | 2012-09-12 | Method: | X-RAY DIFFRACTION (2.018 Å) | Cite: | The crystal structure of acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein from Dyadobacter fermentans DSM 18053 To be Published
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2VD6
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![BU of 2vd6 by Molmil](/molmil-images/mine/2vd6) | Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate. | Descriptor: | 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, ... | Authors: | Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-30 | Release date: | 2007-10-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate. To be Published
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5CFN
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![BU of 5cfn by Molmil](/molmil-images/mine/5cfn) | Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p] | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of Interferon Genes | Authors: | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | Deposit date: | 2015-07-08 | Release date: | 2015-08-26 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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3H4J
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![BU of 3h4j by Molmil](/molmil-images/mine/3h4j) | crystal structure of pombe AMPK KDAID fragment | Descriptor: | SNF1-like protein kinase ssp2 | Authors: | Chen, L, Jiao, Z.-H, Zheng, L.-S, Zhang, Y.-Y, Xie, S.-T, Wang, Z.-X, Wu, J.-W. | Deposit date: | 2009-04-20 | Release date: | 2009-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insight into the autoinhibition mechanism of AMP-activated protein kinase Nature, 459, 2009
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4O82
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![BU of 4o82 by Molmil](/molmil-images/mine/4o82) | |
5BYF
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![BU of 5byf by Molmil](/molmil-images/mine/5byf) | Crystal structure of human ribokinase in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Ribokinase, ... | Authors: | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | Deposit date: | 2015-06-10 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of human ribokinase in complex with AMP To Be Published
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2JJK
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![BU of 2jjk by Molmil](/molmil-images/mine/2jjk) | FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE -1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH A DUAL BINDING AMP SITE INHIBITOR | Descriptor: | FRUCTOSE-1,6-BISPHOSPHATASE 1, N,N'-(heptane-1,7-diyldicarbamoyl)bis(3-chlorobenzenesulfonamide) | Authors: | Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T, Hebeisen, P. | Deposit date: | 2008-04-09 | Release date: | 2008-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric Fbpase Inhibitors Gain 10(5) Times in Potency When Simultaneously Binding Two Neighboring AMP Sites. Bioorg.Med.Chem.Lett., 18, 2008
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2QRD
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![BU of 2qrd by Molmil](/molmil-images/mine/2qrd) | Crystal Structure of the Adenylate Sensor from AMP-activated Protein Kinase in complex with ADP and ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Protein C1556.08c, ... | Authors: | Jin, X, Townley, R, Shapiro, L. | Deposit date: | 2007-07-28 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
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2QRE
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![BU of 2qre by Molmil](/molmil-images/mine/2qre) | Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranotide (ZMP) | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... | Authors: | Jin, X, Townley, R, Shapiro, L. | Deposit date: | 2007-07-28 | Release date: | 2007-10-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
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2QR1
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![BU of 2qr1 by Molmil](/molmil-images/mine/2qr1) | Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Protein C1556.08c, SNF1-like protein kinase ssp2, ... | Authors: | Jin, X, Townley, R, Shapiro, L. | Deposit date: | 2007-07-27 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
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6H7E
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![BU of 6h7e by Molmil](/molmil-images/mine/6h7e) | GEF regulatory domain | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... | Authors: | Ferrandez, Y, Cherfils, J, Peurois, F. | Deposit date: | 2018-07-31 | Release date: | 2020-02-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Membranes prime the RapGEF EPAC1 to transduce cAMP signaling. Nat Commun, 14, 2023
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7XQ2
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![BU of 7xq2 by Molmil](/molmil-images/mine/7xq2) | Structure of hSLC19A1+2'3'-cGAMP | Descriptor: | Reduced folate transporter, cGAMP | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-05-06 | Release date: | 2022-10-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
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2LU4
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![BU of 2lu4 by Molmil](/molmil-images/mine/2lu4) | |
2LU3
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![BU of 2lu3 by Molmil](/molmil-images/mine/2lu3) | |
3TJ7
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![BU of 3tj7 by Molmil](/molmil-images/mine/3tj7) | GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis in complex with AMP | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, GBAA_1210 protein, ... | Authors: | Osipiuk, J, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-08-23 | Release date: | 2011-08-31 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis in complex with AMP To be Published
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3ROU
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![BU of 3rou by Molmil](/molmil-images/mine/3rou) | |
3RPQ
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![BU of 3rpq by Molmil](/molmil-images/mine/3rpq) | |
3RDI
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![BU of 3rdi by Molmil](/molmil-images/mine/3rdi) | |
3RYP
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![BU of 3ryp by Molmil](/molmil-images/mine/3ryp) | |
4O83
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![BU of 4o83 by Molmil](/molmil-images/mine/4o83) | |
4Y5Q
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![BU of 4y5q by Molmil](/molmil-images/mine/4y5q) | |
5ZU7
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![BU of 5zu7 by Molmil](/molmil-images/mine/5zu7) | |
5J3U
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![BU of 5j3u by Molmil](/molmil-images/mine/5j3u) | Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Protein Kinase A | Authors: | El Bakkouri, M, Walker, J.R, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, L, Structural Genomics Consortium (SGC) | Deposit date: | 2016-03-31 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP To Be Published
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8J8O
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![BU of 8j8o by Molmil](/molmil-images/mine/8j8o) | Structure of Acb2 complexed with 2',3'-cGAMP | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, cGAMP, ... | Authors: | Cao, X.L, Xiao, Y, Feng, Y. | Deposit date: | 2023-05-02 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides. Mol.Cell, 84, 2024
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