2BYV
Structure of the cAMP responsive exchange factor Epac2 in its auto- inhibited state
Summary for 2BYV
| Entry DOI | 10.2210/pdb2byv/pdb |
| Related | 1O7F |
| Descriptor | RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 (2 entities in total) |
| Functional Keywords | epac2, camp-gef2, camp, cyclic nucleotide, gef, exchange factor, regulation, auto-inhibition, cdc25 homology domain |
| Biological source | MUS MUSCULUS (MOUSE) |
| Cellular location | Cytoplasm: Q9EQZ6 |
| Total number of polymer chains | 1 |
| Total formula weight | 114150.55 |
| Authors | Rehmann, H.,Wittinghofer, A.,Bos, J.L. (deposition date: 2005-08-08, release date: 2006-02-02, Last modification date: 2023-12-13) |
| Primary citation | Rehmann, H.,Das, J.,Knipscheer, P.,Wittinghofer, A.,Bos, J.L. Structure of the Cyclic-AMP Responsive Exchange Factor Epac2 in its Auto-Inhibited State Nature, 439:625-, 2006 Cited by PubMed: 16452984DOI: 10.1038/NATURE04468 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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