2OUY
crystal structure of pde10a2 mutant D564A in complex with cAMP.
Summary for 2OUY
Entry DOI | 10.2210/pdb2ouy/pdb |
Related | 2OUN 2OUP 2OUQ 2OUR 2OUS 2OUU 2OUV |
Descriptor | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pde, substrate specificity, camp, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9Y233 |
Total number of polymer chains | 2 |
Total formula weight | 77118.82 |
Authors | Wang, H.C.,Liu, Y.D.,Hou, J.,Zheng, M.Y.,Robinson, H. (deposition date: 2007-02-12, release date: 2007-03-20, Last modification date: 2024-04-03) |
Primary citation | Wang, H.,Liu, Y.,Hou, J.,Zheng, M.,Robinson, H.,Ke, H. From the Cover: Structural insight into substrate specificity of phosphodiesterase 10. Proc.Natl.Acad.Sci.Usa, 104:5782-5787, 2007 Cited by PubMed: 17389385DOI: 10.1073/pnas.0700279104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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