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2FD6
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Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
Authors:Huang, M, Huai, Q, Li, Y.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
1IRA
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BU of 1ira by Molmil
COMPLEX OF THE INTERLEUKIN-1 RECEPTOR WITH THE INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-1 RECEPTOR, INTERLEUKIN-1 RECEPTOR ANTAGONIST
Authors:Schreuder, H.A, Tardif, C, Tramp-Kalmeyer, S, Soffientini, A, Sarubbi, E, Akeson, A, Bowlin, T, Yanofsky, S, Barrett, R.W.
Deposit date:1998-04-09
Release date:1998-06-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.
Nature, 386, 1997
2QC1
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Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 A resolution
Descriptor: Acetylcholine receptor subunit alpha, Alpha-bungarotoxin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Dellisanti, C.D, Yao, Y, Stroud, J.C, Wang, Z, Chen, L.
Deposit date:2007-06-18
Release date:2007-08-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.
Nat.Neurosci., 10, 2007
4HMY
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BU of 4hmy by Molmil
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H.
Deposit date:2012-10-18
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
2H2C
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BU of 2h2c by Molmil
Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTWV)
Descriptor: Tight junction protein ZO-1
Authors:Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C.
Deposit date:2006-05-18
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
3MJN
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BU of 3mjn by Molmil
Crystal Structure of the complex of C-lobe of lactoferrin with isopropylamino-3-(1-naphthyloxy)propan-2-ol at 2.38 A Resolution
Descriptor: (1E,2R)-1-(ISOPROPYLIMINO)-3-(1-NAPHTHYLOXY)PROPAN-2-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ...
Authors:Srivastava, K, Vikram, G, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2010-04-13
Release date:2010-06-30
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of the complex of C-lobe of lactoferrin with isopropylamino-3-(1-naphthyloxy)propan-2-ol at 2.38 A Resolution
To be Published
2CZ2
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BU of 2cz2 by Molmil
Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from Mus musculus (form-1 crystal)
Descriptor: GLUTATHIONE, GLYCEROL, Maleylacetoacetate isomerase
Authors:Mizohata, E, Morita, S, Kinoshita, Y, Nagano, K, Uda, H, Uchikubo, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-10
Release date:2006-01-10
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from Mus musculus (form-1 crystal)
To be Published
2I60
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BU of 2i60 by Molmil
Crystal structure of [Phe23]M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B HEAVY CHAIN, ANTIBODY 17B LIGHT CHAIN, ...
Authors:Huang, C.-C, Kwong, P.D.
Deposit date:2006-08-26
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
J.Mol.Biol., 382, 2008
1X70
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BU of 1x70 by Molmil
HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A BETA AMINO ACID INHIBITOR
Descriptor: (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kim, D, Wang, L, Beconi, M, Eiermann, G.J, Fisher, M.H, He, H, Hickey, G.J, Leiting, B, Lyons, K.
Deposit date:2004-08-12
Release date:2005-01-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:(2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
J.Med.Chem., 48, 2005
1OSE
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BU of 1ose by Molmil
Porcine pancreatic alpha-amylase complexed with acarbose
Descriptor: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Gilles, C, Payan, F.
Deposit date:1996-03-20
Release date:1997-04-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of pig pancreatic alpha-amylase isoenzyme II, in complex with the carbohydrate inhibitor acarbose.
Eur.J.Biochem., 238, 1996
2E0M
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BU of 2e0m by Molmil
Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L)
Descriptor: CADMIUM ION, CHLORIDE ION, Ribonuclease
Authors:Yamada, H, Tamada, T, Kosaka, M, Kuroki, R.
Deposit date:2006-10-10
Release date:2007-08-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
1D9O
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BU of 1d9o by Molmil
SOLUTION STRUCTURE OF CECROPIN A(1-8)-MAGAININ 2(1-12) HYBRID PEPTIDE ANALOGUE(P3)
Descriptor: CECROPIN A(1-8)-MAGAININ 2 HYBRID PEPTIDE ANALOGUE
Authors:Oh, D, Kim, Y.
Deposit date:1999-10-29
Release date:1999-11-12
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:NMR structural characterization of cecropin A(1-8) - magainin 2(1-12) and cecropin A (1-8) - melittin (1-12) hybrid peptides.
J.Pept.Res., 53, 1999
1INY
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BU of 1iny by Molmil
A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES
Descriptor: (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:White, C.L, Janakiraman, M.N, Laver, W.G, Philippon, C, Vasella, A, Air, G.M, Luo, M.
Deposit date:1994-09-26
Release date:1995-02-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.
J.Mol.Biol., 245, 1995
1BQM
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BU of 1bqm by Molmil
HIV-1 RT/HBY 097
Descriptor: (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE
Authors:Hsiou, Y, Das, K, Ding, J, Arnold, E.
Deposit date:1998-08-17
Release date:1999-01-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
1BQN
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BU of 1bqn by Molmil
TYR 188 LEU HIV-1 RT/HBY 097
Descriptor: (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE
Authors:Hsiou, Y, Das, K, Ding, J, Arnold, E.
Deposit date:1998-08-17
Release date:1999-01-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
J.Mol.Biol., 284, 1998
3U7B
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BU of 3u7b by Molmil
A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft
Descriptor: 1,2-ETHANEDIOL, ENDO-1,4-BETA-XYLANASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D.
Deposit date:2011-10-13
Release date:2012-07-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft.
Acta Crystallogr.,Sect.D, 68, 2012
2H0Q
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BU of 2h0q by Molmil
Crystal Structure of the PGM domain of the Suppressor of T-Cell receptor (Sts-1)
Descriptor: Suppressor of T-cell receptor signaling 1
Authors:Nassar, N, Ford, B, Carpino, N.
Deposit date:2006-05-15
Release date:2007-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling.
Mol.Cell, 27, 2007
4MHJ
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BU of 4mhj by Molmil
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/goose/Guangdong/1/96 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (6.98 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
2CL8
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BU of 2cl8 by Molmil
Dectin-1 in complex with beta-glucan
Descriptor: CALCIUM ION, CHLORIDE ION, DECTIN-1, ...
Authors:Brown, J, O'Callaghan, C.A, Marshall, A.S.J, Gilbert, R.J.C, Siebold, C, Gordon, S, Brown, G.D, Jones, E.Y.
Deposit date:2006-04-26
Release date:2007-05-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Protein Sci., 16, 2007
1S4N
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BU of 1s4n by Molmil
Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Lobsanov, Y.D, Romero, P.A, Sleno, B, Yu, B, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:2004-01-16
Release date:2004-05-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of Kre2p/Mnt1p: A YEAST {alpha}1,2-MANNOSYLTRANSFERASE INVOLVED IN MANNOPROTEIN BIOSYNTHESIS
J.Biol.Chem., 279, 2004
1S4P
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BU of 1s4p by Molmil
Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p: ternary complex with GDP/Mn and methyl-alpha-mannoside acceptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Lobsanov, Y.D, Romero, P.A, Sleno, B, Yu, B, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:2004-01-16
Release date:2004-05-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of Kre2p/Mnt1p: A YEAST {alpha}1,2-MANNOSYLTRANSFERASE INVOLVED IN MANNOPROTEIN BIOSYNTHESIS
J.Biol.Chem., 279, 2004
2L31
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BU of 2l31 by Molmil
Human PARP-1 zinc finger 2
Descriptor: Poly [ADP-ribose] polymerase 1, ZINC ION
Authors:Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
Deposit date:2010-08-30
Release date:2011-02-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2G2U
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BU of 2g2u by Molmil
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex
Descriptor: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
1D9M
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BU of 1d9m by Molmil
SOLUTION STRUCTURE OF CECROPIN A(1-8)-MAGAININ 2 HYBRID PEPTIDE ANALOGUE(P2)
Descriptor: CECROPIN A(1-8)-MAGAININ 2 HYBRID PEPTIDE ANALOGUE
Authors:Oh, D, Kim, Y.
Deposit date:1999-10-28
Release date:1999-11-12
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:NMR structural characterization of cecropin A(1-8) - magainin 2(1-12) and cecropin A (1-8) - melittin (1-12) hybrid peptides.
J.Pept.Res., 53, 1999
2L30
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BU of 2l30 by Molmil
Human PARP-1 zinc finger 1
Descriptor: Poly [ADP-ribose] polymerase 1, ZINC ION
Authors:Neuhaus, D, Eustermann, S, Yang, J, Videler, H.
Deposit date:2010-08-30
Release date:2011-02-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011

243531

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