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5VAP
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BU of 5vap by Molmil
Crystal structure of eVP30 C-terminus and eNP peptide
Descriptor: Minor nucleoprotein VP30, NP
Authors:XU, W, WU, C, Leung, D.W, Amarasinghe, G.K.
Deposit date:2017-03-27
Release date:2017-06-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.
Nat Commun, 8, 2017
6GHD
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BU of 6ghd by Molmil
Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases
Descriptor: 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ...
Authors:Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S.
Deposit date:2018-05-07
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Nucleic Acids Res., 46, 2018
4ROU
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BU of 4rou by Molmil
Auto-inhibition Mechanism of Human Mitochondrial RNase P Protein Complex
Descriptor: CHLORIDE ION, Mitochondrial ribonuclease P protein 3, ZINC ION
Authors:Li, F, Liu, X, Yang, X, Shen, Y.
Deposit date:2014-10-29
Release date:2015-11-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.713 Å)
Cite:Auto-inhibition Mechanism of Human Mitochondrial RNase P Protein Complex
TO BE PUBLISHED
8ECC
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BU of 8ecc by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2022-09-01
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA
To Be Published
2E5J
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BU of 2e5j by Molmil
Solution structure of RNA binding domain in Methenyltetrahydrofolate synthetase domain containing
Descriptor: Methenyltetrahydrofolate synthetase domain containing
Authors:Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-12-21
Release date:2007-06-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of RNA binding domain in Methenyltetrahydrofolate synthetase domain containing
To be Published
4TU5
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BU of 4tu5 by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1062)
Descriptor: 6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Reeve, S.M, Anderson, A.C.
Deposit date:2014-06-23
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.161 Å)
Cite:Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.
J.Am.Chem.Soc., 137, 2015
5VAO
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BU of 5vao by Molmil
Crystal structure of eVP30 C-terminus and eNP peptide
Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:XU, W, Leung, D.W, Amarasinghe, G.K.
Deposit date:2017-03-27
Release date:2017-06-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.
Nat Commun, 8, 2017
1XWU
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BU of 1xwu by Molmil
Solution structure of ACAUAGA loop
Descriptor: 5'-R(*CP*GP*AP*AP*AP*CP*AP*UP*AP*GP*AP*UP*UP*CP*GP*A)-3'
Authors:Sakamoto, T, Oguro, A, Kawai, G, Ohtsu, T, Nakamura, Y.
Deposit date:2004-11-02
Release date:2005-02-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structures of double loops of an RNA aptamer against mammalian initiation factor 4A
Nucleic Acids Res., 33, 2005
4BK0
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BU of 4bk0 by Molmil
Crystal structure of the KIX domain of human RECQL5 (domain-swapped dimer)
Descriptor: ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER
Authors:Kassube, S.A, Jinek, M, Fang, J, Tsutakawa, S, Nogales, E.
Deposit date:2013-04-21
Release date:2013-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5
Nat.Struct.Mol.Biol., 20, 2013
2CPX
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BU of 2cpx by Molmil
solution structure of RNA binding domain in Hypothetical protein FLJ11016
Descriptor: Hypothetical protein FLJ11016
Authors:Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:solution structure of RNA binding domain in Hypothetical protein FLJ11016
To be Published
2DNG
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BU of 2dng by Molmil
Solution structure of RNA binding domain in Eukaryotic translation initiation factor 4H
Descriptor: Eukaryotic translation initiation factor 4H
Authors:Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-26
Release date:2006-10-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of RNA binding domain in Eukaryotic translation initiation factor 4H
To be Published
1V39
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BU of 1v39 by Molmil
DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
Authors:Hodel, A.E, Gershon, P.D, Quiocho, F.A.
Deposit date:1996-12-16
Release date:1997-09-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
2CQ1
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BU of 2cq1 by Molmil
solution structure of RNA binding domain in PTB-like protein L
Descriptor: PTB-like protein L
Authors:Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:solution structure of RNA binding domain in PTB-like protein L
To be Published
2AEI
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BU of 2aei by Molmil
Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid
Descriptor: 2-({6-{3-[AMINO(IMINO)METHYL]PHENOXY}-3,5-DIFLUORO-4-[(1-METHYL-3-PHENYLPROPYL)AMINO]-2-PYRIDINYL}OXY)BENZOIC ACID, CACODYLATE ION, CALCIUM ION, ...
Authors:Adler, M, Whitlow, M.
Deposit date:2005-07-22
Release date:2006-08-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
Bioorg.Med.Chem.Lett., 15, 2005
2FAP
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BU of 2fap by Molmil
THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-(C16)-ETHOXY RAPAMYCIN COMPLEX INTERACTING WITH HUMA
Descriptor: C49-METHYL RAPAMYCIN, FK506-BINDING PROTEIN, FRAP
Authors:Liang, J, Choi, J, Clardy, J.
Deposit date:1998-09-22
Release date:1999-05-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
2LSL
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BU of 2lsl by Molmil
Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65
Descriptor: Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
2LUY
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BU of 2luy by Molmil
Solution structure of the tandem zinc finger domain of fission yeast Stc1
Descriptor: Meiotic chromosome segregation protein P8B7.28c, ZINC ION
Authors:He, C, Shi, Y, Bayne, E, Wu, J.
Deposit date:2012-06-22
Release date:2013-05-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
4W4V
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BU of 4w4v by Molmil
JNK2/3 in complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Descriptor: 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-Jun N-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4W4Y
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BU of 4w4y by Molmil
JNK2/3 in complex with 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Descriptor: 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-jun NH2-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4W4W
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BU of 4w4w by Molmil
JNK2/3 in complex with N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide
Descriptor: N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide, c-Jun N-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4V30
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BU of 4v30 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Lenalidomide
Descriptor: CEREBLON ISOFORM 4, S-Lenalidomide, ZINC ION
Authors:Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2014-10-15
Release date:2014-12-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
6Y3P
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BU of 6y3p by Molmil
Crystal structure of the C-terminal domain from K. lactis Pby1, an ATP-grasp enzyme interacting with the mRNA decapping enzyme Dcp2
Descriptor: KLLA0B12012p, SULFATE ION
Authors:Graille, M.
Deposit date:2020-02-18
Release date:2020-04-29
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
4V32
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BU of 4v32 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Y101F mutant
Descriptor: CEREBLON ISOFORM 4, S-Thalidomide, ZINC ION
Authors:Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2014-10-15
Release date:2014-12-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
4V31
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BU of 4v31 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Deoxyuridine
Descriptor: 2'-DEOXYURIDINE, CEREBLON ISOFORM 4, CITRATE ANION, ...
Authors:Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2014-10-15
Release date:2014-12-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
4V02
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BU of 4v02 by Molmil
MinC:MinD cell division protein complex, Aquifex aeolicus
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROBABLE SEPTUM SITE-DETERMINING PROTEIN MINC, ...
Authors:Ghosal, D, Lowe, J.
Deposit date:2014-09-10
Release date:2015-01-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mincd Cell Division Proteins Form Alternating Copolymeric Cytomotive Filaments.
Nat.Commun., 5, 2014

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数据于2024-07-17公开中

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