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4YOE
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BU of 4yoe by Molmil
Structure of UP1 bound to RNA 5'-AGU-3'
Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ...
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2015-03-11
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein.
J.Mol.Biol., 427, 2015
6C8U
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BU of 6c8u by Molmil
Solution structure of Musashi2 RRM1
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2024-06-19
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
7SN6
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BU of 7sn6 by Molmil
U2AF65 UHM BOUND TO SF3B155 ULM5
Descriptor: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit
Authors:Loerch, S, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-10-27
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J.Biol.Chem., 298, 2022
4YB1
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BU of 4yb1 by Molmil
20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP
Descriptor: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, MAGNESIUM ION, RNA (91-MER), ...
Authors:Ren, A.M, Patel, D.J, Rajashankar, R.K.
Deposit date:2015-02-18
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
4Z2X
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BU of 4z2x by Molmil
Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-03-30
Release date:2015-04-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution
To be published
3B4M
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BU of 3b4m by Molmil
Crystal Structure of Human PABPN1 RRM
Descriptor: Polyadenylate-binding protein 2
Authors:Ge, H, Zhou, D, Teng, M, Niu, L.
Deposit date:2007-10-24
Release date:2008-01-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008
3BS9
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BU of 3bs9 by Molmil
X-ray structure of human TIA-1 RRM2
Descriptor: IODIDE ION, Nucleolysin TIA-1 isoform p40
Authors:Kumar, A.O, Kielkopf, C.L.
Deposit date:2007-12-22
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.
Biochem.Biophys.Res.Commun., 367, 2008
6DHS
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BU of 6dhs by Molmil
Structure of hnRNP H qRRM1,2
Descriptor: Heterogeneous nuclear ribonucleoprotein H
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2018-05-21
Release date:2018-09-12
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
3BO2
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BU of 3bo2 by Molmil
A relaxed active site following exon ligation by a group I intron
Descriptor: Group I intron P9, MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*G)-3'), ...
Authors:Lipchock, S.V, Strobel, S.A.
Deposit date:2007-12-17
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:A relaxed active site after exon ligation by the group I intron
Proc.Natl.Acad.Sci.Usa, 105, 2008
6DBP
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BU of 6dbp by Molmil
RNA-recognition motif 1 of human MSI2
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Goldgur, Y, Kharas, M.G, Minuesa, G.
Deposit date:2018-05-03
Release date:2019-05-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nat Commun, 10, 2019
3BO3
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BU of 3bo3 by Molmil
A relaxed active site following exon ligation by a group I intron
Descriptor: Group I intron P9, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Lipchock, S.V, Strobel, S.A.
Deposit date:2007-12-17
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A relaxed active site after exon ligation by the group I intron
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BO4
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BU of 3bo4 by Molmil
A relaxed active site following exon ligation by a group I intron
Descriptor: DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*A)-D(P*DG)-3'), DNA/RNA (5'-R(*CP*A)-D(P*DU)-R(P*AP*CP*GP*GP*CP*C)-3'), Group I intron P9, ...
Authors:Lipchock, S.V, Strobel, S.A.
Deposit date:2007-12-17
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:A relaxed active site after exon ligation by the group I intron
Proc.Natl.Acad.Sci.Usa, 105, 2008
4ZKA
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BU of 4zka by Molmil
High Resolution Crystal Structure of Fox1 RRM
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RNA binding protein fox-1 homolog 1, SULFATE ION, ...
Authors:Blatter, M, Allain, F.H.-T.
Deposit date:2015-04-30
Release date:2016-06-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High Resolution Crystal Structure of Fox1 RRM
To Be Published
3B4D
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BU of 3b4d by Molmil
Crystal Structure of Human PABPN1 RRM
Descriptor: Polyadenylate-binding protein 2
Authors:Ge, H, Tong, S, Teng, M, Niu, L.
Deposit date:2007-10-24
Release date:2008-01-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008
3CUL
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BU of 3cul by Molmil
Aminoacyl-tRNA synthetase ribozyme
Descriptor: MAGNESIUM ION, POTASSIUM ION, RNA (92-MER), ...
Authors:Xiao, H, Murakami, H, Suga, H, Ferre-D'Amare, A.R.
Deposit date:2008-04-16
Release date:2008-06-24
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme.
Nature, 454, 2008
6SR7
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BU of 6sr7 by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/K98W
Descriptor: SULFATE ION, U1 small nuclear ribonucleoprotein A
Authors:Rosenbach, H, Span, I.
Deposit date:2019-09-05
Release date:2020-05-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SXW
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BU of 6sxw by Molmil
Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
Descriptor: SULFATE ION, Zinc finger protein 638
Authors:Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2019-09-26
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
To Be Published
6SQV
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BU of 6sqv by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/R70W
Descriptor: SULFATE ION, U1 small nuclear ribonucleoprotein A
Authors:Rosenbach, H, Span, I.
Deposit date:2019-09-04
Release date:2020-05-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SQT
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BU of 6sqt by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Rosenbach, H, Span, I.
Deposit date:2019-09-04
Release date:2020-05-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SQN
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BU of 6sqn by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA
Descriptor: RNA hairpin, U1 small nuclear ribonucleoprotein A
Authors:Rosenbach, H, Span, I.
Deposit date:2019-09-04
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Descriptor: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
Authors:Campagne, S, Allain, F.H.
Deposit date:2019-08-26
Release date:2020-10-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Kang, H.-S, Sattler, M.
Deposit date:2019-12-17
Release date:2020-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SQQ
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BU of 6sqq by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant in complex with RNA obtained by soaking
Descriptor: MAGNESIUM ION, RNA hairpin, U1 small nuclear ribonucleoprotein A
Authors:Rosenbach, H, Span, I.
Deposit date:2019-09-04
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6TZE
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BU of 6tze by Molmil
Human CstF-64 RRM mutant - D50A
Descriptor: Cleavage stimulation factor subunit 2
Authors:Latham, M.P, Masoumzadeh, E.
Deposit date:2019-08-12
Release date:2020-08-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans.
Nucleic Acids Res., 48, 2020

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数据于2024-07-17公开中

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