6TZE
Human CstF-64 RRM mutant - D50A
Summary for 6TZE
| Entry DOI | 10.2210/pdb6tze/pdb |
| Related | 1p1t 6Q2I |
| NMR Information | BMRB: 30653 |
| Descriptor | Cleavage stimulation factor subunit 2 (1 entity in total) |
| Functional Keywords | rna recognition motif, rna cleavage and polyadenylation, rna binding protein, transcription |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 12051.44 |
| Authors | Latham, M.P.,Masoumzadeh, E. (deposition date: 2019-08-12, release date: 2020-08-19, Last modification date: 2024-05-01) |
| Primary citation | Grozdanov, P.N.,Masoumzadeh, E.,Kalscheuer, V.M.,Bienvenu, T.,Billuart, P.,Delrue, M.A.,Latham, M.P.,MacDonald, C.C. A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans. Nucleic Acids Res., 48:9804-9821, 2020 Cited by PubMed: 32816001DOI: 10.1093/nar/gkaa689 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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