3JCE
 
 | | Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | | Descriptor: | 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y. | | Deposit date: | 2015-12-01 | | Release date: | 2016-01-13 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
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3JCJ
 | | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. | | Deposit date: | 2015-12-18 | | Release date: | 2016-03-09 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
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3JCM
 | | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... | | Authors: | Wan, R, Yan, C, Bai, R, Wang, L, Huang, M, Wong, C.C, Shi, Y. | | Deposit date: | 2015-12-23 | | Release date: | 2016-02-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
Science, 351, 2016
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3JCN
 | | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-09 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
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3JCR
 | | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | | Descriptor: | LSm2, LSm3, LSm4, ... | | Authors: | Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. | | Deposit date: | 2016-01-21 | | Release date: | 2016-03-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Molecular architecture of the human U4/U6.U5 tri-snRNP.
Science, 351, 2016
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3MCA
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3MMP
 | | Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | | Descriptor: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | | Authors: | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | | Deposit date: | 2010-04-20 | | Release date: | 2010-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3P26
 | | Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | | Descriptor: | Elongation factor 1 alpha-like protein | | Authors: | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | | Deposit date: | 2010-10-01 | | Release date: | 2010-11-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
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3P27
 | | Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | | Descriptor: | Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE | | Authors: | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | | Deposit date: | 2010-10-01 | | Release date: | 2010-11-17 | | Last modified: | 2012-03-14 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
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3PEN
 | | Structure of archaeal initiation factor aIF2gamma subunit delta 37-47 from Sulfolobus solfataricus in the GDP-bound form. | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Arkhipova, V.I, Lazopulo, A.M, Lazopulo, S.M, Garber, M.B, Nikonov, O.S, Nikonov, S.V, Gabdoulkhakov, A.G. | | Deposit date: | 2010-10-27 | | Release date: | 2011-05-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3005 Å) | | Cite: | Structure of archaeal initiation factor aIF2gamma subunit from Sulfolobus solfataricus in the GDP-bound form.
TO BE PUBLISHED
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3QSY
 | | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea | | Descriptor: | METHIONINE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 subunit alpha, ... | | Authors: | Nikonov, O.S, Stolboushkina, E.A, Zelinskaya, N.V, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | | Deposit date: | 2011-02-22 | | Release date: | 2012-03-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of the archaeal translation initiation factor 2 in complex with a GTP analogue and Met-tRNAf(Met.)
J.Mol.Biol., 425, 2013
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3SJZ
 | | The structure of aIF2gamma subunit delta 41-45 from archaeon Sulfolobus solfataricus complexed with GDP and GDPNP | | Descriptor: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Arkhipova, V.I, Lazopulo, S.M, Lazopulo, A.M, Nikonov, O.S, Stolboushkina, E.A, Gabdoulkhakov, A.G, Garber, M.B, Nikonov, S.V. | | Deposit date: | 2011-06-22 | | Release date: | 2012-07-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | HOLD FOR PUBLICATION
To be Published
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3TR5
 | | Structure of a peptide chain release factor 3 (prfC) from Coxiella burnetii | | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor 3 | | Authors: | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | Deposit date: | 2011-09-09 | | Release date: | 2011-09-28 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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3U2Q
 | | EF-Tu (Escherichia coli) in complex with NVP-LFF571 | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Palestrant, D.J. | | Deposit date: | 2011-10-04 | | Release date: | 2012-05-02 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery of LFF571: an investigational agent for Clostridium difficile infection.
J.Med.Chem., 55, 2012
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3U6B
 | | Ef-tu (escherichia coli) in complex with nvp-ldi028 | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Palestrant, D.J. | | Deposit date: | 2011-10-12 | | Release date: | 2012-02-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
J.Med.Chem., 54, 2011
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3U6K
 | | Ef-tu (escherichia coli) in complex with nvp-ldk733 | | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Palestrant, D.J. | | Deposit date: | 2011-10-12 | | Release date: | 2012-02-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
J.Med.Chem., 54, 2011
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3V11
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3VMF
 | | Archaeal protein | | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kobayashi, K, Saito, K, Ishitani, R, Ito, K, Nureki, O. | | Deposit date: | 2011-12-12 | | Release date: | 2012-07-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for translation termination by archaeal RF1 and GTP-bound EF1alpha complex
Nucleic Acids Res., 40, 2012
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3VNU
 | | Complex structure of viral RNA polymerase I | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2012-01-18 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Mechanism for template-independent terminal adenylation activity of Q beta replicase
Structure, 20, 2012
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3VNV
 | | Complex structure of viral RNA polymerase II | | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2012-01-18 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Mechanism for template-independent terminal adenylation activity of Q beta replicase
Structure, 20, 2012
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3VQT
 | | Crystal structure analysis of the translation factor RF3 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor 3 | | Authors: | Kihira, K, Shomura, Y, Shibata, N, Kitamura, M, Higuchi, Y. | | Deposit date: | 2012-03-30 | | Release date: | 2012-09-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure analysis of the translation factor RF3 (release factor 3)
Febs Lett., 586, 2012
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3VR1
 | | Crystal structure analysis of the translation factor RF3 | | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, Peptide chain release factor 3 | | Authors: | Kihira, K, Shomura, Y, Shibata, N, Kitamura, M, Higuchi, Y. | | Deposit date: | 2012-04-03 | | Release date: | 2012-09-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure analysis of the translation factor RF3 (release factor 3)
Febs Lett., 586, 2012
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3WBI
 | | Crystal structure analysis of eukaryotic translation initiation factor 5B structure I | | Descriptor: | Eukaryotic translation initiation factor 5B | | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | | Deposit date: | 2013-05-20 | | Release date: | 2014-11-19 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A
Acta Crystallogr.,Sect.D, 70, 2014
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3WBJ
 | | Crystal structure analysis of eukaryotic translation initiation factor 5B structure II | | Descriptor: | Eukaryotic translation initiation factor 5B | | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | | Deposit date: | 2013-05-20 | | Release date: | 2014-11-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.495 Å) | | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A
Acta Crystallogr.,Sect.D, 70, 2014
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3WBK
 | | crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex | | Descriptor: | Eukaryotic translation initiation factor 1A, Eukaryotic translation initiation factor 5B | | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | | Deposit date: | 2013-05-20 | | Release date: | 2014-11-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A
Acta Crystallogr.,Sect.D, 70, 2014
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