2LO0
 
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2L5R
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2DF3
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2GVZ
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2JXF
 | | The solution structure of HCV NS4B(40-69) | | Descriptor: | Genome polyprotein | | Authors: | Montserret, R, Penin, F. | | Deposit date: | 2007-11-19 | | Release date: | 2008-11-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Identification of a Novel Determinant for Membrane Association in Hepatitis C Virus Nonstructural Protein 4B
J.Virol., 83, 2009
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2GJ9
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2HAW
 | | Crystal structure of family II Inorganic pyrophosphatase in complex with PNP | | Descriptor: | CHLORIDE ION, FLUORIDE ION, GLYCEROL, ... | | Authors: | Fabrichniy, I.P, Lehtio, L, Oksanen, E, Goldman, A. | | Deposit date: | 2006-06-13 | | Release date: | 2006-11-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A trimetal site and substrate distortion in a family II inorganic pyrophosphatase
J.Biol.Chem., 282, 2007
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2GJ8
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1ECS
 | | THE 1.7 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT ENCODED ON THE TRANSPOSON TN5 | | Descriptor: | BLEOMYCIN RESISTANCE PROTEIN, CALCIUM ION, TETRAETHYLENE GLYCOL | | Authors: | Maruyama, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2000-01-25 | | Release date: | 2001-05-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of the transposon Tn5-carried bleomycin resistance determinant uncomplexed and complexed with bleomycin.
J.Biol.Chem., 276, 2001
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1EK6
 | | STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, TETRAMETHYLAMMONIUM ION, ... | | Authors: | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | | Deposit date: | 2000-03-06 | | Release date: | 2000-05-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Biochemistry, 39, 2000
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1ZCA
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1YT1
 | | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL | | Descriptor: | Endoplasmin, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL | | Authors: | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | | Deposit date: | 2005-02-09 | | Release date: | 2005-06-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
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1ZQ5
 | | Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor EM1404 | | Descriptor: | 3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN, ACETATE ION, Aldo-keto reductase family 1 member C3, ... | | Authors: | Qiu, W, Zhou, M, Ghanmi, D, Luu-The, V, Labrie, F, Lin, S.X. | | Deposit date: | 2005-05-18 | | Release date: | 2006-12-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 282, 2007
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1O23
 | | CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | | Deposit date: | 2003-01-29 | | Release date: | 2003-02-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Alpha-Lactalbumin (La) Stimulates Milk Beta-1,4-Galactosyltransferase I (Beta 4Gal-T1) to Transfer Glucose from Udp-Glucose to N-Acetylglucosamine. Crystal Structure of Beta 4Gal-T1 X La Complex with Udp-Glc.
J.Biol.Chem., 276, 2001
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1NZL
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1YTZ
 | | Crystal structure of skeletal muscle troponin in the Ca2+-activated state | | Descriptor: | ALPHA-[4-(1,1,3,3 - TETRAMETHYLBUTYL)PHENYL]-OMEGA-HYDROXY-POLY(OXY-1,2-ETHANEDIYL), CALCIUM ION, Troponin C, ... | | Authors: | Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J. | | Deposit date: | 2005-02-11 | | Release date: | 2005-04-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1G18
 | | RECA-ADP-ALF4 COMPLEX | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RECA PROTEIN, TETRAFLUOROALUMINATE ION | | Authors: | Datta, S, Prabu, M.M, Vaze, M.B, Ganesh, N, Chandra, N.R, Muniyappa, K, Vijayan, M, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2000-10-11 | | Release date: | 2000-12-11 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADP-AlF(4): implications for decreased ATPase activity and molecular aggregation
Nucleic Acids Res., 28, 2000
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1YSZ
 | | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH NECA | | Descriptor: | Endoplasmin, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, TETRAETHYLENE GLYCOL | | Authors: | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | | Deposit date: | 2005-02-09 | | Release date: | 2005-06-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
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1O73
 | | Tryparedoxin from Trypanosoma brucei | | Descriptor: | TRYPAREDOXIN | | Authors: | Gabrielsen, M, Alphey, M.S, Bond, C.S, Hunter, W.N. | | Deposit date: | 2002-10-23 | | Release date: | 2003-04-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1ZTF
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1OH9
 | | Acetylglutamate kinase from Escherichia coli complexed with MgADP, N-acetyl-L-glutamate and the transition-state mimic AlF4- | | Descriptor: | ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V. | | Deposit date: | 2003-05-23 | | Release date: | 2003-07-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic
J.Mol.Biol., 331, 2003
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1OE2
 | | Atomic Resolution Structure of D92E Mutant of Alcaligenes xylosoxidans Nitrite Reductase | | Descriptor: | COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, TETRAETHYLENE GLYCOL | | Authors: | Ellis, M.J, Dodd, F.E, Sawers, G, Eady, R.R, Hasnain, S.S. | | Deposit date: | 2003-03-18 | | Release date: | 2003-04-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Atomic Resolution Structures of Native Copper Nitrite Reductase from Alcaligenes Xylosoxidans and the Active Site Mutant Asp92Glu
J.Mol.Biol., 328, 2003
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2ABW
 | | Glutaminase subunit of the plasmodial PLP synthase (Vitamin B6 biosynthesis) | | Descriptor: | Pdx2 protein, TETRAETHYLENE GLYCOL | | Authors: | Gengenbacher, M, Fitzpatrick, T.B, Raschle, T, Flicker, K, Sinning, I, Mueller, S, Macheroux, P, Tews, I, Kappes, B. | | Deposit date: | 2005-07-17 | | Release date: | 2006-01-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum: Biochemical and structural insights
J.Biol.Chem., 281, 2006
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1OC9
 | | TRYPAREDOXIN II FROM C.FASCICULATA solved by MR | | Descriptor: | TRYPAREDOXIN II | | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | | Deposit date: | 2003-02-07 | | Release date: | 2003-03-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
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1NMM
 | | beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | | Deposit date: | 2003-01-10 | | Release date: | 2003-01-21 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.
J.Biol.Chem., 276, 2001
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