2DF3
The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl
Summary for 2DF3
| Entry DOI | 10.2210/pdb2df3/pdb |
| Related | 1O7S |
| Descriptor | Sialic acid-binding Ig-like lectin 7, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | siglec, sialic acid, ganglioside, cell adhesion |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 15963.52 |
| Authors | Attrill, H. (deposition date: 2006-02-23, release date: 2006-06-20, Last modification date: 2023-10-25) |
| Primary citation | Attrill, H.,Takazawa, H.,Witt, S.,Kelm, S.,Isecke, R.,Brossmer, R.,Ando, T.,Ishida, H.,Kiso, M.,Crocker, P.R.,van Aalten, D.M.F. The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design Biochem.J., 397:271-278, 2006 Cited by PubMed: 16623661DOI: 10.1042/BJ20060103 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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