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2DF3

The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sialic acid-binding Ig-like lectin 7polymer12714655.31UniProt (Q9Y286)
Pfam (PF07686)
Homo sapiens (Human)Siglec-7,Adhesion inhibitory receptor molecule 1,AIRM-1,CDw328,D-siglec,QA79 membrane protein,p75
2B
(B)
N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched965.91
3C
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
4D
(A)
CYSTEINEnon-polymer121.21Chemie (CYS)
5E
(A)
waterwater18.094Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14655.3
BranchedNumber of molecules1
Total formula weight965.9
Non-Polymers*Number of molecules2
Total formula weight342.4
All*Total formula weight15963.5
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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