1EK6
STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE
Summary for 1EK6
Entry DOI | 10.2210/pdb1ek6/pdb |
Related | 1EK5 |
Descriptor | UDP-GALACTOSE 4-EPIMERASE, MAGNESIUM ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | epimerase, short-chain dehydrogenase, galactosemia, isomerase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 79383.74 |
Authors | Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. (deposition date: 2000-03-06, release date: 2000-05-17, Last modification date: 2024-02-07) |
Primary citation | Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase. Biochemistry, 39:5691-5701, 2000 Cited by PubMed: 10801319DOI: 10.1021/bi000215l PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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