6UY4
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![BU of 6uy4 by Molmil](/molmil-images/mine/6uy4) | Crystal structure of dihydroorotate dehydrogenase from Schistosoma mansoni | Descriptor: | 2-[(4-fluorophenyl)amino]-3-hydroxynaphthalene-1,4-dione, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... | Authors: | Mori, R.M, Zapata, L.C.C, Nonato, M.C. | Deposit date: | 2019-11-11 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni. Febs J., 288, 2021
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5C8N
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![BU of 5c8n by Molmil](/molmil-images/mine/5c8n) | EGFR kinase domain mutant "TMLR" with compound 23 | Descriptor: | Epidermal growth factor receptor, N-{2-[4-(2-aminoethyl)-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine, SULFATE ION | Authors: | Eigenbrot, C, Yu, C. | Deposit date: | 2015-06-25 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. J.Med.Chem., 58, 2015
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7SZD
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![BU of 7szd by Molmil](/molmil-images/mine/7szd) | |
6VET
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![BU of 6vet by Molmil](/molmil-images/mine/6vet) | Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. | Deposit date: | 2020-01-02 | Release date: | 2020-06-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nat.Struct.Mol.Biol., 27, 2020
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7OBY
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![BU of 7oby by Molmil](/molmil-images/mine/7oby) | |
8DHE
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![BU of 8dhe by Molmil](/molmil-images/mine/8dhe) | |
8CRY
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![BU of 8cry by Molmil](/molmil-images/mine/8cry) | |
7T5M
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![BU of 7t5m by Molmil](/molmil-images/mine/7t5m) | Structure of HLA-A*02:01-FLPTPEELGLLGPPRPQVLA complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Interleukin-27 receptor subunit alpha, ... | Authors: | Gras, S. | Deposit date: | 2021-12-12 | Release date: | 2022-12-14 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Cutting Edge: Unconventional CD8 + T Cell Recognition of a Naturally Occurring HLA-A*02:01-Restricted 20mer Epitope. J Immunol., 208, 2022
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6M2R
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![BU of 6m2r by Molmil](/molmil-images/mine/6m2r) | X-ray structure of a functional Drosophila dopamine transporter in L-norepinephrine bound form | Descriptor: | Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, CHLORIDE ION, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-02-28 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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6M30
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![BU of 6m30 by Molmil](/molmil-images/mine/6m30) | Crystal structure of a mutant Staphylococcus equorum manganese superoxide dismutase N73F | Descriptor: | MANGANESE (II) ION, Superoxide dismutase | Authors: | Retnoningrum, D.S, Yoshida, H, Razani, M.D, Meidianto, V.F, Hartanto, A, Artarini, A, Ismaya, W.T. | Deposit date: | 2020-03-02 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Unprecedented Role of The N73-F124 Pair in The Staphylococcus equorum MnSOD Activity. Curr Enzym Inhib, 2021
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8CS0
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![BU of 8cs0 by Molmil](/molmil-images/mine/8cs0) | |
6M38
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![BU of 6m38 by Molmil](/molmil-images/mine/6m38) | X-ray structure of a Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in S-duloxetine bound form | Descriptor: | (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, Antibody fragment 9D5 heavy chain, Antibody fragment 9D5 light chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-02 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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7WLW
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![BU of 7wlw by Molmil](/molmil-images/mine/7wlw) | X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a | Descriptor: | (3S)-1-(4,4-diphenylbut-3-enyl)piperidine-3-carboxylic acid, Antibody Fragment heavy chain, Antibody fragment light chain, ... | Authors: | Penmatsa, A, Joseph, D. | Deposit date: | 2022-01-13 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41, 2022
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6M3Z
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![BU of 6m3z by Molmil](/molmil-images/mine/6m3z) | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in milnacipran bound form | Descriptor: | (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide, Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-04 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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8Q79
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![BU of 8q79 by Molmil](/molmil-images/mine/8q79) | Structure of mBaoJin at pH 6.5 | Descriptor: | CHLORIDE ION, mBaoJin | Authors: | Samygina, V.R, Subach, O.M, Vlaskina, A.V, Nikolaeva, A.Y, Borshchevsky, V, Qin, W, Subach, F.V. | Deposit date: | 2023-08-15 | Release date: | 2023-12-27 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Bright and stable monomeric green fluorescent protein derived from StayGold. Nat.Methods, 21, 2024
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6PG7
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![BU of 6pg7 by Molmil](/molmil-images/mine/6pg7) | |
6VFM
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![BU of 6vfm by Molmil](/molmil-images/mine/6vfm) | Crystal structure of SpeG allosteric polyamine acetyltransferase from Bacillus thuringiensis | Descriptor: | Spermidine N1-acetyltransferase | Authors: | Tsimbalyuk, S, Shornikov, A, Le, V.T.B, Kuhn, M.L, Forwood, J.K. | Deposit date: | 2020-01-05 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | SpeG polyamine acetyltransferase enzyme from Bacillus thuringiensis forms a dodecameric structure and exhibits high catalytic efficiency. J.Struct.Biol., 210, 2020
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6M0Z
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![BU of 6m0z by Molmil](/molmil-images/mine/6m0z) | X-ray structure of Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in L-norepinephrine bound form | Descriptor: | Antibody fragment (Fab) 9D5 Light chain, Antibody fragment (Fab) 9D5 heavy chain, CHLORIDE ION, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-02-24 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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8PP2
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![BU of 8pp2 by Molmil](/molmil-images/mine/8pp2) | |
6M47
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![BU of 6m47 by Molmil](/molmil-images/mine/6m47) | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in tramadol bound form | Descriptor: | (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol, Antibody fragment 9D5 light chain, Antibody fragment Heavy chain, ... | Authors: | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | Deposit date: | 2020-03-05 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.252 Å) | Cite: | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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7OBD
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![BU of 7obd by Molmil](/molmil-images/mine/7obd) | |
6PGD
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![BU of 6pgd by Molmil](/molmil-images/mine/6pgd) | WDR5delta32 bound to peptidomimetic | Descriptor: | N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide, SULFATE ION, WD repeat-containing protein 5 | Authors: | Dennis, M.L, Peat, T.S. | Deposit date: | 2019-06-24 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
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7WGD
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![BU of 7wgd by Molmil](/molmil-images/mine/7wgd) | |
6VFP
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![BU of 6vfp by Molmil](/molmil-images/mine/6vfp) | Crystal structure of human protocadherin 1 EC1-EC4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin-1, ... | Authors: | Brasch, J, Harrison, O.J, Shapiro, L. | Deposit date: | 2020-01-06 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
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6LTB
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![BU of 6ltb by Molmil](/molmil-images/mine/6ltb) | |