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2M1N
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BU of 2m1n by Molmil
Solution structure of a chaperone in type III secretion system
Descriptor: Type III secretion system filament chaperone CesA
Authors:Chen, L, Economou, A, Kalodimos, C.
Deposit date:2012-12-03
Release date:2013-04-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Substrate-Activated Conformational Switch on Chaperones Encodes a Targeting Signal in Type III Secretion.
Cell Rep, 3, 2013
2MLO
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BU of 2mlo by Molmil
Human CCR2 Membrane-Proximal C-Terminal Region (PRO-C) in a Membrane bound form
Descriptor: MCP-1 receptor
Authors:Esaki, K, Yoshinaga, S, Tsuji, T, Toda, E, Terashima, Y, Saitoh, T, Kohda, D, Kohno, T, Osawa, M, Ueda, T, Shimada, I, Matsushima, K, Terasawa, H.
Deposit date:2014-03-04
Release date:2014-10-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT.
Febs J., 281, 2014
2M4J
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BU of 2m4j by Molmil
40-residue beta-amyloid fibril derived from Alzheimer's disease brain
Descriptor: Amyloid beta A4 protein
Authors:Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R.
Deposit date:2013-02-05
Release date:2013-09-25
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue.
Cell(Cambridge,Mass.), 154, 2013
2LXU
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BU of 2lxu by Molmil
Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A
Descriptor: Heterogeneous nuclear ribonucleoprotein H
Authors:Ramelot, T.A, Yang, Y, Pederson, K, Shastry, R, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-31
Release date:2012-10-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A
To be Published
2M52
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BU of 2m52 by Molmil
NMR Structure of the third RNA Recognition Motif (RRM) of U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-02-12
Release date:2013-03-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure of the third RNA Recognition Motif (RRM) of U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
To be Published
2M7O
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BU of 2m7o by Molmil
NMR Structure of the protein NP_346341.1 from Streptococcus pneumoniae
Descriptor: uncharacterized protein
Authors:Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2013-04-29
Release date:2013-05-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure of the protein NP_346341.1 from Streptococcus pneumoniae
To be Published
2M7S
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BU of 2m7s by Molmil
NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1
Descriptor: Serine/arginine-rich splicing factor 1
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-04-29
Release date:2013-05-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1
To be Published
2MCQ
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BU of 2mcq by Molmil
NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
Descriptor: Uncharacterized protein RP812
Authors:Chen, Y, Barnwal, R, Yang, F, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-08-22
Release date:2013-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
To be Published
2M1E
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BU of 2m1e by Molmil
Biosynthetic engineered B28K-B29P human insulin monomer structure in in water solutions.
Descriptor: Insulin
Authors:Bocian, W, Kozerski, L.
Deposit date:2012-11-26
Release date:2013-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
J.Biomol.Nmr, 55, 2013
2MLE
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BU of 2mle by Molmil
NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles
Authors:Robertson, I.M, Baryshnikova, O.K, Mercier, P, Sykes, B.D.
Deposit date:2014-02-26
Release date:2014-03-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
Biochemistry, 47, 2008
2MN2
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BU of 2mn2 by Molmil
3D structure of YmoB, a modulator of biofilm formation
Descriptor: YmoB
Authors:Marimon, O, Cordeiro, T.N, Amata, I, Pons, M.
Deposit date:2014-03-26
Release date:2015-04-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An oxygen-sensitive toxin-antitoxin system.
Nat Commun, 7, 2016
2M07
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BU of 2m07 by Molmil
NMR structure of OmpX in DPC micelles
Descriptor: Outer membrane protein X
Authors:Hagn, F.X, Etzkorn, M, Raschle, T, Wagner, G, Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2012-10-21
Release date:2012-12-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins.
J.Am.Chem.Soc., 135, 2013
2MJC
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BU of 2mjc by Molmil
Zn-binding domain of eukaryotic translation initiation factor 3, subunit G
Descriptor: Eukaryotic translation initiation factor 3 subunit G, ZINC ION
Authors:Al-Abdul-Wahid, M, Menade, M, Xie, J, Kozlov, G, Gehring, K.
Deposit date:2014-01-03
Release date:2015-01-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR structure of the Zn-binding domain of eukaryotic translation initiation factor 3, subunit G
To be Published
2MMB
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BU of 2mmb by Molmil
NMR structure of the protein YP_001712342.1 from Acinetobacter baumannii
Descriptor: Uncharacterized protein
Authors:Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2014-03-14
Release date:2014-04-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the protein YP_002937094.1 from Eubacterium rectale
To be Published
2M5L
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BU of 2m5l by Molmil
Ns5a308
Descriptor: NS5A protein
Authors:Montserret, R, Badillo, A, Hanoulle, X, Lippens, G, Penin, F.
Deposit date:2013-02-27
Release date:2014-03-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ns5a308
To be Published
2MLK
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BU of 2mlk by Molmil
Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae
Descriptor: RstA
Authors:Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T.
Deposit date:2014-03-02
Release date:2014-07-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
4UX1
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BU of 4ux1 by Molmil
Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. AlF)
Descriptor: POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA
Authors:Abe, K, Tani, K, Fujiyoshi, Y.
Deposit date:2014-08-18
Release date:2014-09-17
Last modified:2014-11-12
Method:ELECTRON CRYSTALLOGRAPHY (8 Å)
Cite:Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating.
J.Biol.Chem., 289, 2014
8XGA
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BU of 8xga by Molmil
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((tetrahydro-2H-pyran-4-yl)oxy)indolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-(oxan-4-yloxy)-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.537 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
6WDY
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BU of 6wdy by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Indole Phenylhydroxamate Inhibitor
Descriptor: 1,2-ETHANEDIOL, N-hydroxy-4-[(1H-indol-1-yl)methyl]benzamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-04-01
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase.
Acs Chem.Biol., 15, 2020
4JZW
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BU of 4jzw by Molmil
Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in P212121 space group
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2013-04-03
Release date:2013-06-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.784 Å)
Cite:Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
6WIC
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BU of 6wic by Molmil
Pre-catalytic quaternary complex of human Polymerase Mu on a complementary DNA double-strand break substrate
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kaminski, A.M, Kunkel, T.A, Pedersen, L.C, Bebenek, K.
Deposit date:2020-04-09
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural snapshots of human DNA polymerase mu engaged on a DNA double-strand break.
Nat Commun, 11, 2020
8XFV
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BU of 8xfv by Molmil
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-(piperidin-4-yloxy)indolin-2-one
Descriptor: 3-(1~{H}-benzimidazol-5-ylmethylidene)-4-piperidin-4-yloxy-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-14
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
4JZO
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BU of 4jzo by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27
Descriptor: Anti-HCV E2 Fab HC84-27 heavy chain, Anti-HCV E2 Fab HC84-27 light chain, Envelope glycoprotein E2
Authors:Krey, T, Rey, F.A.
Deposit date:2013-04-03
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Plos Pathog., 9, 2013
4JZC
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BU of 4jzc by Molmil
Angiopoietin-2 fibrinogen domain TAG mutant
Descriptor: Angiopoietin-2
Authors:Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
Deposit date:2013-04-02
Release date:2013-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
9C82
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BU of 9c82 by Molmil
Structure of human ULK1C:PI3KC3-C1 supercomplex
Descriptor: Beclin 1-associated autophagy-related key regulator, Beclin-1, Phosphatidylinositol 3-kinase catalytic subunit type 3, ...
Authors:Chen, M, Hurley, J.H.
Deposit date:2024-06-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (6.84 Å)
Cite:Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023

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数据于2024-08-14公开中

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