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1YZ5
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BU of 1yz5 by Molmil
The crystal structure of 14-3-3-sigma at 2.8 angstrom resolution
Descriptor: 14-3-3 protein sigma
Authors:Benzinger, A, Popowicz, G.M, Holak, T.A, Hermeking, H.
Deposit date:2005-02-28
Release date:2005-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization.
Cell Res., 15, 2005
1AD6
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BU of 1ad6 by Molmil
DOMAIN A OF HUMAN RETINOBLASTOMA TUMOR SUPPRESSOR
Descriptor: RETINOBLASTOMA TUMOR SUPPRESSOR
Authors:Kim, H.Y, Cho, Y.
Deposit date:1997-02-21
Release date:1998-08-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box.
Nat.Struct.Biol., 4, 1997
2AST
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BU of 2ast by Molmil
Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide
Descriptor: BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P.
Deposit date:2005-08-24
Release date:2005-10-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
1B39
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BU of 1b39 by Molmil
HUMAN CYCLIN-DEPENDENT KINASE 2 PHOSPHORYLATED ON THR 160
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CELL DIVISION PROTEIN KINASE 2)
Authors:Brown, N.R, Noble, M.E.M, Lawrie, A.M, Morris, M.C, Tunnah, P, Divita, G, Johnson, L.N, Endicott, J.A.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.
J.Biol.Chem., 274, 1999
1B4T
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BU of 1b4t by Molmil
H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
Descriptor: CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ...
Authors:Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
Deposit date:1998-12-23
Release date:1999-12-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1R36
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BU of 1r36 by Molmil
NMR-based structure of autoinhibited murine Ets-1 deltaN301
Descriptor: C-ets-1 protein
Authors:Lee, G.M, Donaldson, L.W, Pufall, M.A, Kang, H.-S, Pot, I, Graves, B.J, McIntosh, L.P.
Deposit date:2003-09-30
Release date:2004-11-09
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition
J.Biol.Chem., 280, 2005
1B4L
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BU of 1b4l by Molmil
15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
Descriptor: COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION
Authors:Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
Deposit date:1998-12-22
Release date:1999-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1OKW
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BU of 1okw by Molmil
Cyclin A binding groove inhibitor Ac-Arg-Arg-Leu-Asn-(m-Cl-Phe)-NH2
Descriptor: ACE-ARG-ARG-LEU-ASN-FCL-NH2, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
Authors:Kontopidis, G, Andrews, M, McInnes, C, Cowan, A, Powers, H, Innes, L, Plater, A, Griffiths, G, Paterson, D, Zheleva, D, Lane, D, Green, S, Walkinshaw, M, Fischer, P.
Deposit date:2003-07-31
Release date:2003-12-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Structure, 11, 2003
1OL2
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BU of 1ol2 by Molmil
Cyclin A binding groove inhibitor H-Arg-Arg-Leu-Asn-(p-F-Phe)-NH2
Descriptor: ARG-ARG-LEU-ASN-PFF-NH2, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
Authors:Kontopidis, G, Andrews, M, McInnes, C, Cowan, A, Powers, H, Innes, L, Plater, A, Griffiths, G, Paterson, D, Zheleva, D, Lane, D, Green, S, Walkinshaw, M, Fischer, P.
Deposit date:2003-08-05
Release date:2003-12-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Structure, 11, 2003
1OIQ
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BU of 1oiq by Molmil
Imidazopyridines: a potent and selective class of Cyclin-dependent Kinase inhibitors identified through Structure-based hybridisation
Descriptor: CELL DIVISION PROTEIN KINASE 2, N-[4-(2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-YL)-2-PYRIMIDINYL]ACETAMIDE
Authors:Beattie, J.F, Breault, G.A, Byth, K.F, Culshaw, J.D, Ellston, R.P.A, Green, S, Minshull, C.A, Norman, R.A, Pauptit, R.A, Thomas, A.P, Jewsbury, P.J.
Deposit date:2003-06-24
Release date:2003-09-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Imidazo[1,2-A]Pyridines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors Identified Through Structure-Based Hybridisation
Bioorg.Med.Chem.Lett., 13, 2003
5HR3
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BU of 5hr3 by Molmil
Crystal structure of thioredoxin N106A mutant
Descriptor: COPPER (II) ION, ETHANOL, SULFATE ION, ...
Authors:Noguera, M.E, Vazquez, D.S, Howard, E.I, Cousido-Siah, A, Mitschler, A, Podjarny, A, Santos, J.
Deposit date:2016-01-22
Release date:2017-02-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Structural variability of E. coli thioredoxin captured in the crystal structures of single-point mutants.
Sci Rep, 7, 2017
1BHI
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BU of 1bhi by Molmil
STRUCTURE OF TRANSACTIVATION DOMAIN OF CRE-BP1/ATF-2, NMR, 20 STRUCTURES
Descriptor: CRE-BP1
Authors:Nagadoi, A, Nakazawa, K, Uda, H, Maekawa, T, Ishii, S, Nishimura, Y.
Deposit date:1998-06-09
Release date:1999-06-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the transactivation domain of ATF-2 comprising a zinc finger-like subdomain and a flexible subdomain.
J.Mol.Biol., 287, 1999
2ATX
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BU of 2atx by Molmil
Crystal Structure of the TC10 GppNHp complex
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, small GTP binding protein TC10
Authors:Hemsath, L, Dvorsky, R, Fiegen, D, Carlier, M.F, Ahmadian, M.R.
Deposit date:2005-08-26
Release date:2005-09-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An electrostatic steering mechanism of Cdc42 recognition by Wiskott-Aldrich syndrome proteins
Mol.Cell, 20, 2005
1BI8
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BU of 1bi8 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR
Authors:Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1B0F
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BU of 1b0f by Molmil
CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE WITH MDL 101, 146
Descriptor: 1-{3-METHYL-2-[4-(MORPHOLINE-4-CARBONYL)-BENZOYLAMINO]-BUTYRYL}-PYRROLIDINE-2-CARBOXYLIC ACID (3,3,4,4,4-PENTAFLUORO-1-ISOPROPYL-2-OXO-BUTYL)-AMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (ELASTASE)
Authors:Schreuder, H.A, Metz, W.A, Peet, N.P, Pelton, J.T, Tardif, C.
Deposit date:1998-11-09
Release date:1998-11-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.
J.Med.Chem., 41, 1998
1PYX
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BU of 1pyx by Molmil
GSK-3 Beta complexed with AMP-PNP
Descriptor: Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-07-09
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J.Mol.Biol., 333, 2003
1Q03
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BU of 1q03 by Molmil
Crystal structure of FGF-1, S50G/V51G mutant
Descriptor: Heparin-binding growth factor 1
Authors:Kim, J, Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1AJY
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BU of 1ajy by Molmil
STRUCTURE AND MOBILITY OF THE PUT3 DIMER: A DNA PINCER, NMR, 13 STRUCTURES
Descriptor: PUT3, ZINC ION
Authors:Walters, K.J, Dayie, K.T, Reece, R.J, Ptashne, M, Wagner, G.
Deposit date:1997-05-12
Release date:1997-09-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and mobility of the PUT3 dimer.
Nat.Struct.Biol., 4, 1997
2AJ4
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BU of 2aj4 by Molmil
Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP
Descriptor: CHLORIDE ION, Galactokinase, MAGNESIUM ION, ...
Authors:Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M.
Deposit date:2005-08-01
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer
J.Biol.Chem., 280, 2005
2ALC
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BU of 2alc by Molmil
ETHANOL REGULON TRANSCRIPTIONAL ACTIVATOR DNA-BINDING DOMAIN FROM ASPERGILLUS NIDULANS
Descriptor: PROTEIN (ETHANOL REGULON TRANSCRIPTIONAL ACTIVATOR), ZINC ION
Authors:Cerdan, R, Cahuzac, B, Felenbok, B, Guittet, E.
Deposit date:1999-01-20
Release date:2000-01-21
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR solution structure of AlcR (1-60) provides insight in the unusual DNA binding properties of this zinc binuclear cluster protein.
J.Mol.Biol., 295, 2000
2B0U
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BU of 2b0u by Molmil
The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
1AW6
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BU of 1aw6 by Molmil
GAL4 (CD), NMR, 24 STRUCTURES
Descriptor: CADMIUM ION, GAL4 (CD)
Authors:Baleja, J.D, Wagner, G.
Deposit date:1997-10-10
Release date:1998-04-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination.
J.Biomol.NMR, 10, 1997
1AQ1
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BU of 1aq1 by Molmil
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR STAUROSPORINE
Descriptor: CYCLIN-DEPENDENT PROTEIN KINASE 2, STAUROSPORINE
Authors:Endicott, J.A, Noble, M.E.M, Johnson, L.N, Lawrie, A, Tunnah, P, Brown, N.R.
Deposit date:1997-08-05
Release date:1997-11-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.
Nat.Struct.Biol., 4, 1997
1XAW
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BU of 1xaw by Molmil
crystal structure of the cytoplasmic distal C-terminal domain of occludin
Descriptor: Occludin
Authors:Li, Y, Fanning, A.S, Anderson, J.M, Lavie, A.
Deposit date:2004-08-26
Release date:2005-09-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the Conserved Cytoplasmic C-terminal Domain of Occludin: Identification of the ZO-1 Binding Surface.
J.Mol.Biol., 352, 2005
1XWD
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BU of 1xwd by Molmil
Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle stimulating hormone receptor, ...
Authors:Fan, Q.R, Hendrickson, W.A.
Deposit date:2004-10-30
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of human follicle-stimulating hormone in complex with its receptor.
Nature, 433, 2005

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