PDB: 71589 resultsInfo pagesStatus searchChemie searchBIRD

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7ZR0	CryoEM structure of HSP90-CDC37-BRAF(V600E) complex. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-14 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
8A01	Bacteriophage phiCjT23 major capsid protein trimer type 1 Descriptor: Major capsid protein P5 Authors: Rissanen, I, Kejzar, N, Huiskonen, J.T. Deposit date: 2022-05-26 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A04	Bacteriophage phiCjT23 major capsid protein trimer type 4 Descriptor: Major capsid protein P5 Authors: Rissanen, I, Kejzar, N, Huiskonen, J.T. Deposit date: 2022-05-26 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A03	Bacteriophage phiCjT23 major capsid protein trimer type 3 Descriptor: Major capsid protein P5 Authors: Rissanen, I, Kejzar, N, Huiskonen, J.T. Deposit date: 2022-05-26 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A8R	Crystal structure of TEAD4 in complex with YAP peptide Descriptor: Isoform 7 of Transcriptional coactivator YAP1, MYRISTIC ACID, Transcriptional enhancer factor TEF-3 Authors: Scheufler, C, Kallen, J. Deposit date: 2022-06-23 Release date: 2022-12-28 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.696 Å) Cite: N-terminal beta-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor. Protein Sci., 32, 2023
183L	SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, INDENE, ... Authors: Morton, A, Matthews, B.W. Deposit date: 1995-04-19 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995
1N9A	Farnesyltransferase complex with tetrahydropyridine inhibitors Descriptor: 1-{2-[3-(4-CYANO-BENZYL)-3H-IMIDAZOL-4-YL]-ACETYL}-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... Authors: Gwaltney II, S.L, O'Conner, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. Deposit date: 2002-11-22 Release date: 2003-01-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. Bioorg.Med.Chem.Lett., 13, 2003
8A8Q	Crystal structure of Protein Scalloped in complex with YAP peptide Descriptor: ACETATE ION, Isoform 7 of Transcriptional coactivator YAP1, Protein scalloped Authors: Scheufler, C, Villard, F. Deposit date: 2022-06-23 Release date: 2022-12-28 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.465 Å) Cite: N-terminal beta-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor. Protein Sci., 32, 2023
7ZQY	Chaetomium thermophilum Rad50 Zn hook Descriptor: DH domain-containing protein, ZINC ION Authors: Lammens, K, Rotheneder, M, Stakyte, K. Deposit date: 2022-05-03 Release date: 2022-12-28 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-28 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR1	Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) Descriptor: DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... Authors: Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. Deposit date: 2022-05-03 Release date: 2023-01-11 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
1WUT	Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes Descriptor: 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID, Glycogen phosphorylase, muscle form, ... Authors: Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.-J, Herling, A.W, Oikonomakos, N.G, Kosmopoulou, M.N, Schmoll, D, Sarubbi, E, von Roedern, E, Schonafinger, K, Defossa, E. Deposit date: 2004-12-08 Release date: 2005-12-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs Protein Sci., 14, 2005
3IIY	Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide Descriptor: Histone H1K26 peptide, Polycomb protein EED Authors: Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. Deposit date: 2009-08-03 Release date: 2009-09-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
3IML	Crystal Structure Of S-Adenosylmethionine Synthetase From Burkholderia Pseudomallei Descriptor: S-adenosylmethionine synthetase Authors: Staker, B.L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-08-10 Release date: 2009-09-22 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
8A16	Human PTPRM domains FN3-4, in spacegroup P212121 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E. Deposit date: 2022-05-31 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
8A1F	Human PTPRK N-terminal domains MAM-Ig-FN1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. Deposit date: 2022-06-01 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3 Å) Cite: Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
8A17	Human PTPRM domains FN3-4, in spacegroup P3221 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ... Authors: Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E. Deposit date: 2022-05-31 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
4XI1	Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ... Authors: Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2015-01-06 Release date: 2015-01-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.983 Å) Cite: Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
4XGU	Structure of C. elegans PCH-2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Putative pachytene checkpoint protein 2, SULFATE ION Authors: Ye, Q, Corbett, K.D. Deposit date: 2015-01-02 Release date: 2015-05-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.301 Å) Cite: TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. Elife, 4, 2015
4XKX	Crystal structure of BACE1 in complex with 2-aminooxazoline 3-azaxanthene inhibitor 28 Descriptor: (5S)-7-(2-fluoropyridin-3-yl)-3-(2-fluoropyridin-4-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... Authors: Whittington, D.A, Long, A.M. Deposit date: 2015-01-12 Release date: 2015-02-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious beta-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorg.Med.Chem.Lett., 25, 2015
4XL8	Crystal Structure of Human Adenovirus 52 Short Fiber Knob in Complex with 2-O-Methyl-5-N-Acetylneuraminic Acid Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, ... Authors: Stehle, T, Liaci, A.M. Deposit date: 2015-01-13 Release date: 2015-01-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells. Plos Pathog., 11, 2015
3I9G	Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, CALCIUM ION, MAGNESIUM ION, ... Authors: Huxford, T. Deposit date: 2009-07-10 Release date: 2009-09-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc.Natl.Acad.Sci.USA, 106, 2009
3VZ7	Crystal Structure Analysis of the mini-chaperonin variant with Pro 187 Gly Descriptor: 60 kDa chaperonin Authors: Saijo, S, Sato, T. Deposit date: 2012-10-09 Release date: 2013-11-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding Energy(BE) from Crystal Packing of Mini-chaperones (mcpn) Provided Insights into the Allosteric Interaction of GroEL/ES Complex To be Published
1O63	Crystal structure of an ATP phosphoribosyltransferase Descriptor: ATP phosphoribosyltransferase Authors: Structural GenomiX Deposit date: 2003-10-23 Release date: 2003-11-11 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
1O6C	Crystal structure of UDP-N-acetylglucosamine 2-epimerase Descriptor: UDP-N-acetylglucosamine 2-epimerase Authors: Structural GenomiX Deposit date: 2003-11-03 Release date: 2003-11-25 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005

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