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2FPS
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BU of 2fps by Molmil
Crystal structure of the N-terminal domain of E.coli HisB- Apo Ca model.
Descriptor: CALCIUM ION, CHLORIDE ION, Histidine biosynthesis bifunctional protein hisB, ...
Authors:Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2006-01-17
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.Biol.Chem., 281, 2006
2LF7
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BU of 2lf7 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436
Descriptor: Transcription factor ETV6
Authors:Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
Deposit date:2011-06-28
Release date:2012-05-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
1RHP
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BU of 1rhp by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLATELET FACTOR 4
Descriptor: PLATELET FACTOR 4
Authors:Chen, L, Zhang, X.
Deposit date:1994-09-16
Release date:1994-11-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of recombinant human platelet factor 4.
Biochemistry, 33, 1994
2FPR
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BU of 2fpr by Molmil
Crystal structure the N-terminal domain of E. coli HisB. Apo Mg model.
Descriptor: BROMIDE ION, Histidine biosynthesis bifunctional protein hisB, MAGNESIUM ION, ...
Authors:Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2006-01-17
Release date:2006-09-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.Biol.Chem., 281, 2006
1RHG
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BU of 1rhg by Molmil
THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS
Descriptor: GRANULOCYTE COLONY-STIMULATING FACTOR
Authors:Hill, C.P, Osslund, T.D, Eisenberg, D.
Deposit date:1993-01-29
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors.
Proc.Natl.Acad.Sci.USA, 90, 1993
2L7M
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BU of 2l7m by Molmil
Solution Structure of the Pitx2 Homeodomain R24H mutant
Descriptor: Pituitary homeobox 2
Authors:Doerdelmann, T, Rance, M, Kojetin, D.J, Baird-Titus, J.M.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of the Pitx2 Homeodomain R24H mutant
To be Published
2L6Y
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BU of 2l6y by Molmil
haddock model of GATA1NF:Lmo2LIM2-Ldb1LID
Descriptor: Erythroid transcription factor, LIM domain only 2, linker, ...
Authors:Wilkinson-White, L, Gamsjaeger, R, Dastmalchi, S, Wienert, B, Stokes, P.H, Crossley, M, Mackay, J.P, Matthews, J.M.
Deposit date:2010-12-01
Release date:2011-08-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Proc.Natl.Acad.Sci.USA, 108, 2011
1T69
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BU of 1t69 by Molmil
Crystal Structure of human HDAC8 complexed with SAHA
Descriptor: Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ZINC ION
Authors:Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W.
Deposit date:2004-05-05
Release date:2004-07-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
1T6R
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BU of 1t6r by Molmil
Solution structure of TM1442, a putative anti sigma factor antagonist in phosphorylated state
Descriptor: Putative anti-sigma factor antagonist TM1442
Authors:Etezady-Esfarjani, T, Placzek, W, Herrmann, T, Lesley, S.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2004-05-07
Release date:2005-05-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structures of the putative anti-sigma-factor antagonist TM1442 from Thermotoga maritima in the free and phosphorylated states.
Magn.Reson.Chem., 44 Spec No, 2006
1TI7
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BU of 1ti7 by Molmil
CRYSTAL STRUCTURE OF NMRA, A NEGATIVE TRANSCRIPTIONAL REGULATOR, IN COMPLEX WITH NADP AT 1.7A RESOLUTION
Descriptor: CHLORIDE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Lamb, H.K, Leslie, K, Dodds, A.L, Nutley, M, Cooper, A, Johnson, C, Thompson, P, Stammers, D.K, Hawkins, A.R.
Deposit date:2004-06-02
Release date:2004-06-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides.
J.Biol.Chem., 278, 2003
1PGR
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BU of 1pgr by Molmil
2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR
Descriptor: PROTEIN (G-CSF RECEPTOR), PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR)
Authors:Aritomi, M, Kunishima, N, Okamoto, T, Kuroki, R, Ota, Y, Morikawa, K.
Deposit date:1999-03-08
Release date:2000-03-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme.
Nature, 401, 1999
2KO3
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BU of 2ko3 by Molmil
Nedd8 solution structure
Descriptor: NEDD8
Authors:Choi, Y.S, Jeon, Y.H, Cheong, C.
Deposit date:2009-09-09
Release date:2009-11-03
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:60th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkage.
Febs Lett., 583, 2009
2KR0
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BU of 2kr0 by Molmil
Solution structure of the proteasome ubiquitin receptor Rpn13
Descriptor: Proteasomal ubiquitin receptor ADRM1
Authors:Chen, X, Lee, B, Finley, D, Walters, K.J.
Deposit date:2009-11-25
Release date:2010-05-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2.
Mol.Cell, 38, 2010
2KBM
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BU of 2kbm by Molmil
Ca-S100A1 interacting with TRTK12
Descriptor: CALCIUM ION, F-actin-capping protein subunit alpha-2, Protein S100-A1
Authors:Wright, N.T, Varney, K.M, Cannon, B.R, Morgan, M, Weber, D.J.
Deposit date:2008-12-02
Release date:2009-02-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of Ca-S100A1-TRTK12
To be Published
1Q3W
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BU of 1q3w by Molmil
GSK-3 Beta complexed with Alsterpaullone
Descriptor: 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-08-01
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1PUE
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BU of 1pue by Molmil
PU.1 ETS DOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*GP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*CP*CP*TP*TP*TP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR PU.1 (TF PU.1))
Authors:Kodandapani, R, Pio, F, Ni, C.Z, Piccialli, G, Klemsz, M, McKercher, S, Maki, R.A, Ely, K.R.
Deposit date:1996-07-08
Release date:1997-02-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex.
Nature, 380, 1996
1Q41
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BU of 1q41 by Molmil
GSK-3 Beta complexed with Indirubin-3'-monoxime
Descriptor: (Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-08-01
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1POG
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BU of 1pog by Molmil
SOLUTION STRUCTURE OF THE OCT-1 POU-HOMEO DOMAIN DETERMINED BY NMR AND RESTRAINED MOLECULAR DYNAMICS
Descriptor: OCT-1 POU HOMEODOMAIN DNA-BINDING PROTEIN
Authors:Cox, M, Van Tilborg, P.J.A, De Laat, W, Boelens, R, Van Leeuwen, H.C, Van Der Vliet, P.C, Kaptein, R.
Deposit date:1994-10-12
Release date:1995-07-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.
J.Biomol.NMR, 6, 1995
1PYC
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BU of 1pyc by Molmil
CYP1 (HAP1) DNA-BINDING DOMAIN (RESIDUES 60-100), NMR, 15 STRUCTURES
Descriptor: CYP1, ZINC ION
Authors:Timmerman, J, Vuidepot, A.-L, Bontems, F, Lallemand, J.-Y, Gervais, M, Shechter, E, Guiard, B.
Deposit date:1996-02-17
Release date:1996-08-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:1H, 15N resonance assignment and three-dimensional structure of CYP1 (HAP1) DNA-binding domain.
J.Mol.Biol., 259, 1996
1PIN
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BU of 1pin by Molmil
PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ...
Authors:Noel, J.P, Ranganathan, R, Hunter, T.
Deposit date:1998-06-21
Release date:1998-10-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent.
Cell(Cambridge,Mass.), 89, 1997
2MWB
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BU of 2mwb by Molmil
FBP28 WW2 mutant W457F
Descriptor: Transcription elongation regulator 1
Authors:Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T.
Deposit date:2014-11-03
Release date:2014-12-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements.
Proc.Natl.Acad.Sci.USA, 111, 2014
2N4U
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BU of 2n4u by Molmil
NMR structure of Fbp28 WW domain E454Y mutant
Descriptor: Transcription elongation regulator 1
Authors:Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A.
Deposit date:2015-07-01
Release date:2015-10-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Preventing fibril formation of a protein by selective mutation.
Proc.Natl.Acad.Sci.USA, 112, 2015
2N4R
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BU of 2n4r by Molmil
NMR structure of Fbp28 WW domain L453D mutant
Descriptor: Transcription elongation regulator 1
Authors:Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A.
Deposit date:2015-07-01
Release date:2015-10-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Preventing fibril formation of a protein by selective mutation.
Proc.Natl.Acad.Sci.USA, 112, 2015
1RZY
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BU of 1rzy by Molmil
Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine
Descriptor: 5'-O-(N-ETHYL-SULFAMOYL)ADENOSINE, Histidine triad nucleotide-binding protein 1
Authors:Krakowiak, A.K, Pace, H.C, Blackburn, G.M, Adams, M, Mekhalfia, A, Kaczmarek, R, Baraniak, J, Stec, W.J, Brenner, C.
Deposit date:2003-12-29
Release date:2004-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors
J.Biol.Chem., 279, 2004
1SVP
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BU of 1svp by Molmil
SINDBIS VIRUS CAPSID PROTEIN
Descriptor: SINDBIS VIRUS CAPSID PROTEIN
Authors:Lee, S, Rossmann, M.G.
Deposit date:1996-03-22
Release date:1996-08-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly.
Structure, 4, 1996

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