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8E8J	Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mg2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*CP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8B	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8G	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 180s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8D	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E85	Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mn2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*CP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8C	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8F	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 120s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E89	Human DNA polymerase eta-DNA-rU-ended primer-binary complex Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*U)-3') Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8H	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 300s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8E	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 90s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E88	Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8K	Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mg2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Chang, C, Gao, Y. Deposit date: 2022-08-25 Release date: 2023-02-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
4ECV	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 230 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.521 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED7	Human DNA polymerase eta - DNA ternary complex: TG crystal at pH 7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.717 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECR	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 40 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.892 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECY	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 6.0 (Na+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.943 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECU	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 200 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED6	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 6.7 for 15 hr, Sideway translocation Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.211 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED2	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 7.2 (Na+ HEPES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.711 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED8	Human DNA polymerase eta - DNA ternary complex: Reaction in the TG crystal at pH 7.0, Normal translocation Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.521 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECQ	Human DNA polymerase eta- DNA ternary complex: AT crystal at pH6.8(K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ECW	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 250 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.896 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED1	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 7.0 (Na+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.806 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4EEY	Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ... Authors: Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2012-03-28 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy. Nat.Struct.Mol.Biol., 19, 2012
4ECT	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 140 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.795 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012

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