PDB: 153 resultsInfo pagesStatus searchChemie searchBIRD

---

6X2W	Crystal Structure of PKINES peptide bound to CRM1(E571K) Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-21 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.001 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2U	Crystal Structure of PKINES peptide bound to CRM1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-21 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2S	Crystal Structure of Mek1(NQ)NES peptide bound to CRM Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-20 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.496 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2M	Crystal Structure of unliganded CRM1-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-20 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.351 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2P	Crystal Structure of the Mek1NES peptide bound to CRM1 Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-20 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2V	Crystal Structure of PKI(DE)NES peptide bound to CRM1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-21 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.822 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2O	Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1 Descriptor: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-20 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.551 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2X	Crystal Structure of Mek1NES peptide bound to CRM1(E571K) Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-21 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.458 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2Y	Crystal Structure of mDia2NES peptide bound to CRM1(E571K) Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-21 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.304 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2R	Crystal Structure of the 4E-TNES peptide bound to CRM1 Descriptor: Eukaryotic translation initiation factor 4E transporter, Exportin-1, GLYCEROL, ... Authors: Baumhardt, J.M. Deposit date: 2020-05-20 Release date: 2020-07-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.299 Å) Cite: Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-08-16 Release date: 2012-10-17 Last modified: 2012-12-12 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAY	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GPT	Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-08-21 Release date: 2012-09-05 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia, 27, 2013
4HAX	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAV	Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 Descriptor: Anguinomycin A, bound form, CHLORIDE ION, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB2	Crystal structure of CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAU	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAW	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... Authors: Sun, Q, Chook, Y.M. Deposit date: 2012-09-27 Release date: 2013-01-09 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
5TQC	Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4) Descriptor: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1 Authors: Huber, F.M, Hoelz, A. Deposit date: 2016-10-23 Release date: 2017-02-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular basis for protection of ribosomal protein L4 from cellular degradation. Nat Commun, 8, 2017
5UWI	Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... Authors: Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-02-21 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.143 Å) Cite: Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

<1234567>