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6N89
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BU of 6n89 by Molmil
Cryo-EM structure of the Importin beta:Histone H1.0 complex
Descriptor: Histone H1.0, Importin subunit beta-1
Authors:Bilokapic, S, Ivic, N, Halic, M.
Deposit date:2018-11-28
Release date:2019-02-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Fuzzy Interactions Form and Shape the Histone Transport Complex.
Mol. Cell, 73, 2019
6N88
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BU of 6n88 by Molmil
Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex
Descriptor: Histone H1.0, Importin subunit beta-1, MGC52556 protein
Authors:Bilokapic, S, Ivic, N, Halic, M.
Deposit date:2018-11-28
Release date:2019-02-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fuzzy Interactions Form and Shape the Histone Transport Complex.
Mol. Cell, 73, 2019
6N1Z
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BU of 6n1z by Molmil
Importin-9 bound to H2A-H2B
Descriptor: Histone H2A, Histone H2B 1.1, Importin-9
Authors:Tomchick, D.R, Chook, Y.M, Padavannil, A.
Deposit date:2018-11-12
Release date:2019-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
6CIT
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BU of 6cit by Molmil
Crystal Structure of MVM NS2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2018-02-25
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.027 Å)
Cite:Correlation of CRM1-NES affinity with nuclear export activity.
Mol. Biol. Cell, 29, 2018
6X2S
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BU of 6x2s by Molmil
Crystal Structure of Mek1(NQ)NES peptide bound to CRM
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2M
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BU of 6x2m by Molmil
Crystal Structure of unliganded CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2P
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BU of 6x2p by Molmil
Crystal Structure of the Mek1NES peptide bound to CRM1
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2V
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BU of 6x2v by Molmil
Crystal Structure of PKI(DE)NES peptide bound to CRM1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.822 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2O
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BU of 6x2o by Molmil
Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2X
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BU of 6x2x by Molmil
Crystal Structure of Mek1NES peptide bound to CRM1(E571K)
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.458 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2Y
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BU of 6x2y by Molmil
Crystal Structure of mDia2NES peptide bound to CRM1(E571K)
Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2R
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BU of 6x2r by Molmil
Crystal Structure of the 4E-TNES peptide bound to CRM1
Descriptor: Eukaryotic translation initiation factor 4E transporter, Exportin-1, GLYCEROL, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
5XOJ
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BU of 5xoj by Molmil
Crystal structure of Xpo1p-PKI-Nup42p-Gsp1p-GTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Koyama, M, Shirai, N, Matsuura, Y.
Deposit date:2017-05-29
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p
Genes Cells, 22, 2017
5YST
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BU of 5yst by Molmil
RanM189D in complex with RanBP1-CRM1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Zhang, Y.
Deposit date:2017-11-15
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:RanM189D in complex with RanBP1-CRM1
To Be Published
5YSU
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BU of 5ysu by Molmil
Plumbagin in complex with CRM1-RanM189D-RanBP1
Descriptor: (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Zhang, Y.
Deposit date:2017-11-15
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RanL182A in complex with RanBP1-CRM1
To Be Published
5YRO
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BU of 5yro by Molmil
RanL182A in complex with RanBP1-CRM1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Zhang, Y.
Deposit date:2017-11-09
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:RanL182A in complex with RanBP1-CRM1
To Be Published
5YTB
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BU of 5ytb by Molmil
RanY197A in complex with RanBP1-CRM1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Sun, Q, Zhang, Y.
Deposit date:2017-11-17
Release date:2018-11-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RanY197A in complex with RanBP1-CRM1
To Be Published
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVH
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BU of 5yvh by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YU6
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BU of 5yu6 by Molmil
CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX
Descriptor: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ...
Authors:Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E.
Deposit date:2017-11-20
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
5YVI
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BU of 5yvi by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5ZPU
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BU of 5zpu by Molmil
LFS829 in complex with CRM1-Ran-RanBP1
Descriptor: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Lei, Y.
Deposit date:2018-04-16
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:To be published
To Be Published
5TQC
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BU of 5tqc by Molmil
Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4)
Descriptor: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1
Authors:Huber, F.M, Hoelz, A.
Deposit date:2016-10-23
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Nat Commun, 8, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.342 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017

223790

数据于2024-08-14公开中

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