6X2X
Crystal Structure of Mek1NES peptide bound to CRM1(E571K)
Summary for 6X2X
Entry DOI | 10.2210/pdb6x2x/pdb |
Descriptor | GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (8 entities in total) |
Functional Keywords | nuclear export, crm1, xpo1, exportin-1, protein transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 160915.56 |
Authors | Baumhardt, J.M. (deposition date: 2020-05-21, release date: 2020-07-01, Last modification date: 2023-10-18) |
Primary citation | Baumhardt, J.M.,Walker, J.S.,Lee, Y.,Shakya, B.,Brautigam, C.A.,Lapalombella, R.,Grishin, N.,Chook, Y.M. Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31:1879-1891, 2020 Cited by PubMed: 32520643DOI: 10.1091/mbc.E20-04-0233 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.458 Å) |
Structure validation
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