6X2V

Crystal Structure of PKI(DE)NES peptide bound to CRM1

Summary for 6X2V

• Entry DOI: 10.2210/pdb6x2v/pdb
• Descriptor: GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (7 entities in total)
• Functional Keywords: nuclear export, crm1, xpo1, exportin-1, protein transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 160692.25

Authors

Baumhardt, J.M. (deposition date: 2020-05-21, release date: 2020-07-01, Last modification date: 2023-10-18)

• Primary citation: Baumhardt, J.M.,Walker, J.S.,Lee, Y.,Shakya, B.,Brautigam, C.A.,Lapalombella, R.,Grishin, N.,Chook, Y.M.; Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.; Mol.Biol.Cell, 31:1879-1891, 2020; PubMed: 32520643; DOI: 10.1091/mbc.E20-04-0233

Experimental method

X-RAY DIFFRACTION (2.822 Å)