3F4F
| Crystal structure of dUT1p, a dUTPase from Saccharomyces cerevisiae | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Singer, A.U, Evdokimova, E, Kudritska, M, Edwards, A.M, Yakunin, A.F, Savchenko, A. | Deposit date: | 2008-10-31 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437, 2011
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3EHW
| Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, dUTP pyrophosphatase | Authors: | Takacs, E, Barabas, O, Vertessy, B.G. | Deposit date: | 2008-09-15 | Release date: | 2008-09-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site To be Published
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3ECY
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3CA9
| Evolution of chlorella virus dUTPase | Descriptor: | DEOXYURIDINE-5'-DIPHOSPHATE, Deoxyuridine triphosphatase, MAGNESIUM ION | Authors: | Yamanishi, M, Homma, K, Zhang, Y, Etten, L.V.J, Moriyama, H. | Deposit date: | 2008-02-19 | Release date: | 2009-03-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallization and crystal-packing studies of Chlorella virus deoxyuridine triphosphatase. Acta Crystallogr.,Sect.F, 65, 2009
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3C3I
| Evolution of chlorella virus dUTPase | Descriptor: | DEOXYURIDINE-5'-DIPHOSPHATE, Deoxyuridine triphosphatase, MAGNESIUM ION | Authors: | Yamanishi, M, Homma, K, Zhang, Y, Etten, L.V.J, Moriyama, H. | Deposit date: | 2008-01-28 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallization and crystal-packing studies of Chlorella virus deoxyuridine triphosphatase. Acta Crystallogr.,Sect.F, 65, 2009
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3C2T
| Evolution of chlorella virus dUTPase | Descriptor: | DEOXYURIDINE-5'-DIPHOSPHATE, Deoxyuridine triphosphatase, MAGNESIUM ION | Authors: | Yamanishi, M, Homma, K, Zhang, Y, Etten, L.V.J, Moriyama, H. | Deposit date: | 2008-01-25 | Release date: | 2009-02-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallization and crystal-packing studies of Chlorella virus deoxyuridine triphosphatase. Acta Crystallogr.,Sect.F, 65, 2009
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2ZDC
| Crystal structure of dUTPase from Sulfolobus tokodaii | Descriptor: | 167aa long hypothetical dUTPase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION | Authors: | Kanagawa, M, Baba S, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-11-21 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of dUTPase from Sulfolobus tokodaii To be Published
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2V9X
| E138D variant of Escherichia coli dCTP deaminase in complex with dUTP | Descriptor: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Thymark, M, Johansson, E, Larsen, S, Willemoes, M. | Deposit date: | 2007-08-28 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutational Analysis of the Nucleotide Binding Site of Escherichia Coli Dctp Deaminase. Arch.Biochem.Biophys., 470, 2008
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2QXX
| Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP | Descriptor: | Deoxycytidine triphosphate deaminase, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Christophersen, S, Harris, P, Willemoes, M. | Deposit date: | 2007-08-13 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis. J.Mol.Biol., 376, 2008
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2QLP
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2PY4
| Full length structure of the Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP. | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Barabas, O, Nagy, N, Takacs, E, Vertessy, B.G. | Deposit date: | 2007-05-15 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor. Biochem.Biophys.Res.Commun., 373, 2008
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2YZJ
| Crystal structure of dCTP deaminase from Sulfolobus tokodaii | Descriptor: | 167aa long hypothetical dUTPase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE-5'-DIPHOSPHATE, ... | Authors: | Kanagawa, M, Baba, S, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-06 | Release date: | 2007-11-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structure of dCTP deaminase from Sulfolobus tokodaii To be Published
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2PC5
| Native crystal structure analysis on Arabidopsis dUTPase | Descriptor: | DUTP pyrophosphatase-like protein, MAGNESIUM ION | Authors: | Moriyama, H, Bajaj, M. | Deposit date: | 2007-03-29 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana. Acta Crystallogr.,Sect.F, 63, 2007
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2OL0
| High Resolution Crystal Structures of Vaccinia Virus dUTPase | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DEOXYURIDINE-5'-DIPHOSPHATE, ... | Authors: | Schormann, N, Chattopadhyay, D. | Deposit date: | 2007-01-18 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OL1
| High Resolution Crystal Structures of Vaccinia Virus dUTPase | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, ... | Authors: | Schormann, N, Chattopadhyay, D. | Deposit date: | 2007-01-18 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OKE
| High Resolution Crystal Structures of Vaccinia Virus dUTPase | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Schormann, N, Chattopadhyay, D. | Deposit date: | 2007-01-16 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OKB
| High Resolution Crystal Structures of Vaccinia Virus dUTPase | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Schormann, N, Chattopadhyay, D. | Deposit date: | 2007-01-16 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OKD
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2J4Q
| Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP | Descriptor: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-09-05 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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2J4H
| Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme | Descriptor: | DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-08-31 | Release date: | 2007-08-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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2HXB
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2HXD
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2HRM
| Crystal structure of dUTPase complexed with substrate analogue methylene-dUTP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXY-5'-O-[(S)-HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]URIDINE, Deoxyuridine 5'-triphosphate nucleotidohydrolase | Authors: | Barabas, O, Kovari, J, Tapai, R, Vertessy, B.G. | Deposit date: | 2006-07-20 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. Proteins, 71, 2008
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2HQU
| Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Barabas, O, Varga, B, Vertessy, B.G. | Deposit date: | 2006-07-19 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase. Febs Lett., 581, 2007
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2HR6
| Crystal structure of dUTPase in complex with substrate analogue dUDP and manganese | Descriptor: | 1,2-ETHANEDIOL, DEOXYURIDINE-5'-DIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Barabas, O, Kovari, J, Tapai, R, Vertessy, B.G. | Deposit date: | 2006-07-19 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. Proteins, 71, 2008
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