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5CL6
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BU of 5cl6 by Molmil
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (33% substrate/67% product at 72 hours)
Descriptor: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
3O6R
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BU of 3o6r by Molmil
Crystal Structure of 4-Chlorocatechol Dioxygenase from Rhodococcus opacus 1CP in complex with pyrogallol
Descriptor: (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, BENZENE-1,2,3-TRIOL, Chlorocatechol 1,2-dioxygenase, ...
Authors:Ferraroni, M, Briganti, F, Kolomitseva, M, Golovleva, L.
Deposit date:2010-07-29
Release date:2011-08-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: new perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity.
J. Struct. Biol., 181, 2013
5CL5
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BU of 5cl5 by Molmil
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (51% substrate/49% product at 48 hours)
Descriptor: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.569 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
3F6K
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BU of 3f6k by Molmil
Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with neurotensin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Neurotensin, ...
Authors:Quistgaard, E.M, Madsen, P, Groftehauge, M.K, Nissen, P, Petersen, C.M, Thirup, S.
Deposit date:2008-11-06
Release date:2008-12-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain.
Nat.Struct.Mol.Biol., 16, 2009
5CLC
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BU of 5clc by Molmil
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer B)
Descriptor: AlkD, DNA (5'-D(*AP*AP*GP*CP*CP*(DZM)P*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*GP*GP*CP*T)-3')
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
3NJL
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BU of 3njl by Molmil
D116A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis, at pH7.5
Descriptor: MAGNESIUM ION, Peptidase
Authors:Osipiuk, J, Mulligan, R, Bargassa, M, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-06-17
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase.
J.Biol.Chem., 287, 2012
2OXF
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BU of 2oxf by Molmil
X-ray structure of the unliganded uridine phosphorylase from Salmonella typhimurium in homodimeric form at 1.76A resolution
Descriptor: GLYCEROL, Uridine phosphorylase
Authors:Timofeev, V.I, Pavlyk, B.P, Lashkov, A.A, Gabdoulkhakov, A.G, Mikhailov, A.M.
Deposit date:2007-02-20
Release date:2008-02-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:X-ray structure of the unliganded uridine phosphorylase from Salmonella typhimurium in homodimeric form at 1.76A resolution
To be Published
5JZB
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BU of 5jzb by Molmil
Crystal structure of HsaD bound to 3,5-dichlorobenzene sulphonamide
Descriptor: 3,5-dichlorobenzene-1-sulfonamide, 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase, PHOSPHATE ION
Authors:Ryan, A, Polycarpou, E, Lack, N.A, Evangelopoulos, D, Sieg, C, Halman, A, Bhakta, S, Sinclair, A, Eleftheriadou, O, McHugh, T.D, Keany, S, Lowe, E, Ballet, R, Abihammad, A, Ciulli, A, Sim, E.
Deposit date:2016-05-16
Release date:2017-04-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.
Br. J. Pharmacol., 174, 2017
4I2V
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BU of 4i2v by Molmil
X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution
Descriptor: Uridine phosphorylase
Authors:Lashkov, A.A, Balaev, V.V, Prokofev, I.I, Betzel, C, Gabdoulkhakov, A.G, Mikhailov, A.M.
Deposit date:2012-11-23
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.121 Å)
Cite:X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution
To be Published
3NJJ
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BU of 3njj by Molmil
P115A mutant of SO1698 protein, an aspartic peptidase from Shewanella oneidensis
Descriptor: Peptidase
Authors:Osipiuk, J, Mulligan, R, Bargassa, M, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-06-17
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase.
J.Biol.Chem., 287, 2012
3WJL
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BU of 3wjl by Molmil
Crystal structure of IIb selective Fc variant, Fc(V12), in complex with FcgRIIb
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-c, ...
Authors:Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K.
Deposit date:2013-10-11
Release date:2013-11-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131.
Protein Eng.Des.Sel., 26, 2013
3NJZ
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BU of 3njz by Molmil
Crystal Structure of Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans Adducts with salicylate
Descriptor: 2-HYDROXYBENZOIC ACID, FE (II) ION, GLYCEROL, ...
Authors:Ferraroni, M, Briganti, F, Matera, I.
Deposit date:2010-06-18
Release date:2011-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases.
J.Struct.Biol., 177, 2012
2OIV
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BU of 2oiv by Molmil
Structural Analysis of Xanthomonas XopD Provides Insights Into Substrate Specificity of Ubiquitin-like Protein Proteases
Descriptor: PHOSPHATE ION, Xanthomonas outer protein D
Authors:Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
Deposit date:2007-01-11
Release date:2007-05-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
3WOY
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BU of 3woy by Molmil
Crystal structure of CLASP2 TOG domain (TOG2)
Descriptor: CLIP-associating protein 2
Authors:Hayashi, I, Maki, T.
Deposit date:2014-01-06
Release date:2015-05-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics
J. Mol. Biol., 427, 2015
2GMO
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BU of 2gmo by Molmil
NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Descriptor: Polymerase basic protein 2
Authors:Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J.
Deposit date:2006-04-07
Release date:2007-02-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007
3WAT
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BU of 3wat by Molmil
Crystal structure of 4-O-beta-D-mannosyl-D-glucose phosphorylase MGP complexed with Man+Glc
Descriptor: 4-O-beta-D-mannosyl-D-glucose phosphorylase, PHOSPHATE ION, beta-D-glucopyranose, ...
Authors:Nakae, S, Ito, S, Higa, M, Senoura, T, Wasaki, J, Hijikata, A, Shionyu, M, Ito, S, Shirai, T.
Deposit date:2013-05-08
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Novel Enzyme in Mannan Biodegradation Process 4-O-beta-d-Mannosyl-d-Glucose Phosphorylase MGP
J.Mol.Biol., 425, 2013
3NL1
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BU of 3nl1 by Molmil
Crystal Structure of Salicylate 1,2-dioxygenase from Pseudoaminobacter salicylatoxidans Adducts with gentisate
Descriptor: 2,5-dihydroxybenzoic acid, FE (II) ION, GLYCEROL, ...
Authors:Ferraroni, M, Briganti, F, Matera, I.
Deposit date:2010-06-21
Release date:2011-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.155 Å)
Cite:Crystal structures of salicylate 1,2-dioxygenase-substrates adducts: A step towards the comprehension of the structural basis for substrate selection in class III ring cleaving dioxygenases.
J.Struct.Biol., 177, 2012
1XXR
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BU of 1xxr by Molmil
Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose
Descriptor: ACETIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Rabijns, A, Barre, A, Van Damme, E.J.M, Peumans, W.J, De Ranter, C.J, Rouge, P.
Deposit date:2004-11-08
Release date:2005-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose
Febs J., 272, 2005
4IQC
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BU of 4iqc by Molmil
P3121 crystal form of FKBP12.6
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B
Authors:Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
Deposit date:2013-01-11
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
3T71
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BU of 3t71 by Molmil
Crystal Structure of Steccherinum ochraceum Laccase obtained by multi-crystals composite data collection technique (90% dose)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
Authors:Ferraroni, M, Briganti, F, Matera, I, Kolomytseva, M, Golovleva, L, Scozzafava, A, Chernykh, A.M.
Deposit date:2011-07-29
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Reaction intermediates and redox state changes in a blue laccase from Steccherinum ochraceum observed by crystallographic high/low X-ray dose experiments.
J.Inorg.Biochem., 111, 2012
2EM2
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BU of 2em2 by Molmil
Solution structure of the C2H2 type zinc finger (region 584-616) of human Zinc finger protein 28 homolog
Descriptor: ZINC ION, Zinc finger protein 28 homolog
Authors:Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-28
Release date:2007-10-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the C2H2 type zinc finger (region 584-616) of human Zinc finger protein 28 homolog
To be Published
2OIX
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BU of 2oix by Molmil
Xanthomonas XopD C470A Mutant
Descriptor: Xanthomonas outer protein D
Authors:Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
Deposit date:2007-01-11
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
2EMH
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BU of 2emh by Molmil
Solution structure of the C2H2 type zinc finger (region 491-523) of human Zinc finger protein 484
Descriptor: ZINC ION, Zinc finger protein 484
Authors:Tomizawa, T, Tochio, N, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-28
Release date:2007-10-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the C2H2 type zinc finger (region 491-523) of human Zinc finger protein 484
To be Published
2EN1
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BU of 2en1 by Molmil
Solution structure of the C2H2 type zinc finger (region 563-595) of human Zinc finger protein 224
Descriptor: ZINC ION, Zinc finger protein 224
Authors:Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-28
Release date:2007-10-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the C2H2 type zinc finger (region 563-595) of human Zinc finger protein 224
To be Published
2E8M
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BU of 2e8m by Molmil
Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8
Descriptor: Epidermal growth factor receptor kinase substrate 8
Authors:Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-01-22
Release date:2007-07-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8
To be Published

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数据于2024-09-04公开中

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