5CLC

Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer B)

Summary for 5CLC

• Entry DOI: 10.2210/pdb5clc/pdb
• Related: 5CL3 5CL4 5CL5 5CL6 5CL7 5CL8 5CL9 5CLA 5CLB 5CLD 5CLE
• Descriptor: AlkD, DNA (5'-D(*AP*AP*GP*CP*CP*(DZM)P*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*GP*GP*CP*T)-3'), ... (4 entities in total)
• Functional Keywords: dna glycosylase, heat-like repeat, protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Bacillus cereus; More
• Total number of polymer chains: 3
• Total formula weight: 34063.69

Authors

Mullins, E.A.,Eichman, B.F. (deposition date: 2015-07-16, release date: 2015-10-28, Last modification date: 2023-09-27)

• Primary citation: Mullins, E.A.,Shi, R.,Parsons, Z.D.,Yuen, P.K.,David, S.S.,Igarashi, Y.,Eichman, B.F.; The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.; Nature, 527:254-258, 2015; PubMed: 26524531; DOI: 10.1038/nature15728

Experimental method

X-RAY DIFFRACTION (1.729 Å)