6V76
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v76 by Molmil](/molmil-images/mine/6v76) | Crystal Structure of Human PKM2 in Complex with L-valine | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Nandi, S, Dey, M. | Deposit date: | 2019-12-07 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2. J.Biol.Chem., 295, 2020
|
|
7Y3B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y3b by Molmil](/molmil-images/mine/7y3b) | Crystal structure of TRIM7 bound to GN1 | Descriptor: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | Authors: | Dong, C, Yan, X. | Deposit date: | 2022-06-10 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7E87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e87 by Molmil](/molmil-images/mine/7e87) | |
7Y3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y3c by Molmil](/molmil-images/mine/7y3c) | Crystal structure of TRIM7 bound to RACO-1 | Descriptor: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | Authors: | Dong, C, Yan, X. | Deposit date: | 2022-06-10 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
8C7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7d by Molmil](/molmil-images/mine/8c7d) | Structure of the GEF Kalirin DH2 Domain | Descriptor: | Kalirin | Authors: | Callens, M.C, Thompson, A.P, Gray, J.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-01-14 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure-based alignment and analysis of RHO selectivity of RHO-DBL GTPase exchange factors to be published
|
|
7E8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8g by Molmil](/molmil-images/mine/7e8g) | |
7E89
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e89 by Molmil](/molmil-images/mine/7e89) | |
7ELG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7elg by Molmil](/molmil-images/mine/7elg) | LC3B modificated with a covalent probe | Descriptor: | 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Fan, S, Wan, W. | Deposit date: | 2021-04-10 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
7E8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8b by Molmil](/molmil-images/mine/7e8b) | CryoEM structure of human Kv4.2-DPP6S complex | Descriptor: | Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 | Authors: | Kise, Y, Nureki, O. | Deposit date: | 2021-03-01 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
|
|
6V75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v75 by Molmil](/molmil-images/mine/6v75) | Crystal Structure of Human PKM2 in Complex with L-aspartate | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ASPARTIC ACID, CHLORIDE ION, ... | Authors: | Nandi, S, Dey, M. | Deposit date: | 2019-12-07 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2. J.Biol.Chem., 295, 2020
|
|
7VPX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vpx by Molmil](/molmil-images/mine/7vpx) | The cryo-EM structure of the human pre-A complex | Descriptor: | 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-10-18 | Release date: | 2023-05-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
|
|
7BV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bv6 by Molmil](/molmil-images/mine/7bv6) | Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex | Descriptor: | Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8 | Authors: | Li, Y, Pan, L.F. | Deposit date: | 2020-04-09 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8CIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cia by Molmil](/molmil-images/mine/8cia) | |
6UYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uys by Molmil](/molmil-images/mine/6uys) | Crystal structure of K37-acetylated SUMO1 in complex with phosphorylated PML-SIM | Descriptor: | Protein PML, Small ubiquitin-related modifier 1 | Authors: | Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G. | Deposit date: | 2019-11-14 | Release date: | 2019-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner. Structure, 28, 2020
|
|
6SIE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sie by Molmil](/molmil-images/mine/6sie) | Crystal structure of the C-lobe of drosophila Arc 2 | Descriptor: | Activity-regulated cytoskeleton associated protein 2, SULFATE ION | Authors: | Hallin, E.I, Kursula, P. | Deposit date: | 2019-08-09 | Release date: | 2019-08-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc. Plos One, 16, 2021
|
|
7BT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bt6 by Molmil](/molmil-images/mine/7bt6) | |
7YG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yg6 by Molmil](/molmil-images/mine/7yg6) | Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-11 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yfx by Molmil](/molmil-images/mine/7yfx) | Cryo-EM structure of Hili in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-09 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ygn by Molmil](/molmil-images/mine/7ygn) | Cryo-EM structure of the Mili in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-11 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yfq by Molmil](/molmil-images/mine/7yfq) | Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | Descriptor: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-08 | Release date: | 2024-02-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
6E49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e49 by Molmil](/molmil-images/mine/6e49) | Pif1 peptide bound to PCNA trimer | Descriptor: | ATP-dependent DNA helicase PIF1, Proliferating cell nuclear antigen | Authors: | Buzovetsky, O, Kwon, Y, Pham, N.T, Kim, C, Ira, G, Sung, P, Xiong, Y. | Deposit date: | 2018-07-17 | Release date: | 2018-08-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Role of the Pif1-PCNA Complex in Pol delta-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication. Cell Rep, 21, 2017
|
|
7BYJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7byj by Molmil](/molmil-images/mine/7byj) | Crystal structure of the FERM domain of FRMPD4 | Descriptor: | FERM and PDZ domain-containing protein 4 | Authors: | Lin, L, Wang, M, Wang, C, Zhu, J. | Deposit date: | 2020-04-23 | Release date: | 2020-12-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability. Biochem.J., 477, 2020
|
|
6F9S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f9s by Molmil](/molmil-images/mine/6f9s) | |
6F9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f9w by Molmil](/molmil-images/mine/6f9w) | |
7Z0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z0g by Molmil](/molmil-images/mine/7z0g) | CPAP:TUBULIN:IE5 ALPHAREP COMPLEX P1 SPACE GROUP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Centromere protein J, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Gigant, B, Campanacci, V. | Deposit date: | 2022-02-22 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.487 Å) | Cite: | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|