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2VNU
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BU of 2vnu by Molmil
Crystal structure of Sc Rrp44
Descriptor: 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP)-3', EXOSOME COMPLEX EXONUCLEASE RRP44, MAGNESIUM ION, ...
Authors:Lorentzen, E, Basquin, J, Conti, E.
Deposit date:2008-02-07
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the Rnase II Nuclease Family
Mol.Cell, 29, 2008
4NGG
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BU of 4ngg by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-A and UU-3' ends (2.6 Angstrom resolution)
Descriptor: 5'-R(*AP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer, PHOSPHATE ION
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGC
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BU of 4ngc by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UA-3' ends (2.1 Angstrom resolution)
Descriptor: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*A)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH6
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BU of 4nh6 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 15-mer siRNA having 5'-pUUU and UU-3' ends (2.55 Angstrom resolution)
Descriptor: 5'-R(P*UP*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGF
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BU of 4ngf by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 17-mer siRNA having 5'-p and UU-3' ends (3.1 Angstrom resolution)
Descriptor: 5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGB
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BU of 4ngb by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UU-3' ends (2.25 Angstrom resolution)
Descriptor: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
6ELI
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BU of 6eli by Molmil
Structure of HIV-1 reverse transcriptase (RT) in complex with rilpivirine and an RNase H inhibitor XZ462
Descriptor: 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, Gag-Pol polyprotein, ...
Authors:Das, K, Arnold, E.
Deposit date:2017-09-29
Release date:2018-04-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
J. Virol., 92, 2018
1MY9
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BU of 1my9 by Molmil
Solution structure of a K+ cation stabilized dimeric RNA quadruplex containing two G:G(:A):G:G(:A) hexads, G:G:G:G tetrads and UUUU loops
Descriptor: 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3'
Authors:Liu, H, Matsugami, A, Katahira, M, Uesugi, S.
Deposit date:2002-10-04
Release date:2003-10-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002
7O6N
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BU of 7o6n by Molmil
Crystal structure of C. elegans ERH-2 PID-3 complex
Descriptor: Enhancer of rudimentary homolog 2, FORMIC ACID, Protein pid-3
Authors:Falk, S, Ketting, R.F.
Deposit date:2021-04-11
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
5GVQ
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BU of 5gvq by Molmil
Solution structure of the first RRM domain of human spliceosomal protein SF3b49
Descriptor: Splicing factor 3B subunit 4
Authors:Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2016-09-06
Release date:2017-04-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment.
Protein Sci., 26, 2017
5U6H
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BU of 5u6h by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1
Descriptor: Muscleblind-like protein 1, ZINC ION
Authors:Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
Deposit date:2016-12-08
Release date:2017-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
3TPZ
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BU of 3tpz by Molmil
2.1 Angstrom crystal structure of the L114P mutant of E. Coli KsgA
Descriptor: CHLORIDE ION, PHOSPHATE ION, Ribosomal RNA small subunit methyltransferase A
Authors:Scarsdale, J.N, Musayev, F.N, Rife, J.P.
Deposit date:2011-09-08
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Control of Substrate Specificity by a Single Active Site Residue of the KsgA Methyltransferase.
Biochemistry, 51, 2012
2KTQ
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BU of 2ktq by Molmil
OPEN TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'), DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Li, Y, Waksman, G.
Deposit date:1998-07-30
Release date:1999-01-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.
EMBO J., 17, 1998
8W1I
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BU of 8w1i by Molmil
Cryo-EM structure of BTV subcore
Descriptor: Core protein VP3
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-16
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
5U6L
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BU of 5u6l by Molmil
Solution structure of the zinc fingers 3 and 4 of MBNL1
Descriptor: Muscleblind-like protein 1, ZINC ION
Authors:Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
Deposit date:2016-12-08
Release date:2017-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
8W19
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BU of 8w19 by Molmil
Cryo-EM structure of BTV star-subcore
Descriptor: Core protein VP3, VP6
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-15
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
2HXY
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BU of 2hxy by Molmil
Crystal structure of human apo-eIF4AIII
Descriptor: Probable ATP-dependent RNA helicase DDX48
Authors:Johansen, J.S, Andersen, G.R.
Deposit date:2006-08-04
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
1DZF
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BU of 1dzf by Molmil
RPB5 from S.cerevisiae
Descriptor: DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1
Authors:Todone, F, Weinzierl, R.O.J, Brick, P, Onesti, S.
Deposit date:2000-02-25
Release date:2000-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Transcription Factor Interaction Target
Proc.Natl.Acad.Sci.USA, 97, 2000
8ASW
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BU of 8asw by Molmil
Cryo-EM structure of yeast Elp123 in complex with alanine tRNA
Descriptor: 5'-DEOXYADENOSINE, Alanine tRNA, Elongator complex protein 1, ...
Authors:Jaciuk, M, Scherf, D, Kaszuba, K, Gaik, M, Koscielniak, A, Krutyholowa, R, Rawski, M, Indyka, P, Biela, A, Dobosz, D, Lin, T.-Y, Abbassi, N, Hammermeister, A, Chramiec-Glabik, A, Kosinski, J, Schaffrath, R, Glatt, S.
Deposit date:2022-08-21
Release date:2022-12-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM structure of the fully assembled Elongator complex.
Nucleic Acids Res., 51, 2023
3ICX
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BU of 3icx by Molmil
Crystal structure of Sulfolobus solfataricus Nop5 (135-380)
Descriptor: Pre mRNA splicing protein, SULFATE ION
Authors:Ye, K.
Deposit date:2009-07-19
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009
5O7H
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BU of 5o7h by Molmil
Structure of the Cascade-I-Fv complex from Shewanella putrefaciens
Descriptor: CRISPR-associated protein, Csy4 family, Cas5fv, ...
Authors:Pausch, P, Altegoer, F, Bange, G.
Deposit date:2017-06-08
Release date:2017-08-16
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell, 67, 2017
8W12
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BU of 8w12 by Molmil
Cryo-EM structure of VP3-VP6 heterohexamer
Descriptor: Core protein VP3, VP6
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-14
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1C
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BU of 8w1c by Molmil
Cryo-EM structure of BTV pre-subcore
Descriptor: Core protein VP3, VP6
Authors:Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
Deposit date:2024-02-15
Release date:2024-04-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
5W5H
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BU of 5w5h by Molmil
Human IFIT1 dimer with m7Gppp-AAAA
Descriptor: Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3')
Authors:Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B.
Deposit date:2017-06-15
Release date:2017-07-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
7XWZ
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BU of 7xwz by Molmil
Crystal structure of SARS-CoV-2 N-NTD and dsRNA complex
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Nucleoprotein, ...
Authors:Luan, X.D, Li, X.M, Li, Y.F.
Deposit date:2022-05-27
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.
Sci Bull (Beijing), 67, 2022

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数据于2024-09-18公开中

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