4LRX
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![BU of 4lrx by Molmil](/molmil-images/mine/4lrx) | Crystal Structure of the E.coli DhaR(N)-DhaK complex | Descriptor: | GLYCEROL, PTS-dependent dihydroxyacetone kinase operon regulatory protein, PTS-dependent dihydroxyacetone kinase, ... | Authors: | Shi, R, McDonald, L, Cygler, M, Ekiel, I. | Deposit date: | 2013-07-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure, 22, 2014
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2H46
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3N4E
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![BU of 3n4e by Molmil](/molmil-images/mine/3n4e) | CRYSTAL STRUCTURE OF mandelate racemase/muconate lactonizing protein from Paracoccus denitrificans Pd1222 | Descriptor: | CALCIUM ION, CHLORIDE ION, Mandelate racemase/muconate lactonizing enzyme, ... | Authors: | Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-21 | Release date: | 2010-06-09 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CRYSTAL STRUCTURE OF mandelate racemase/muconate lactonizing protein from Paracoccus denitrificans
Pd1222 To be Published
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2P57
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![BU of 2p57 by Molmil](/molmil-images/mine/2p57) | GAP domain of ZNF289, an ID1-regulated zinc finger protein | Descriptor: | GTPase-activating protein ZNF289, UNKNOWN ATOM OR ION, ZINC ION | Authors: | Tong, Y, Dimov, S, Shen, L, Zhu, H, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2007-03-14 | Release date: | 2007-03-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | GAP domain of ZNF289, an ID1-regulated zinc finger protein To be Published
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2OXL
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![BU of 2oxl by Molmil](/molmil-images/mine/2oxl) | Structure and Function of the E. coli Protein YmgB: a Protein Critical for Biofilm Formation and Acid Resistance | Descriptor: | Hypothetical protein ymgB, octyl beta-D-glucopyranoside | Authors: | Page, R, Peti, W, Woods, T.K, Palermino, J.M, Doshi, O. | Deposit date: | 2007-02-20 | Release date: | 2007-10-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and Function of the Escherichia coli Protein YmgB: A Protein Critical for Biofilm Formation and Acid-resistance. J.Mol.Biol., 373, 2007
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3GI5
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![BU of 3gi5 by Molmil](/molmil-images/mine/3gi5) | Crystal structure of protease inhibitor, KB62 in complex with wild type HIV-1 protease | Descriptor: | (5S)-3-(3-Acetylphenyl)-N-[(1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)pr opyl]-2-oxo-5-oxazolidinecarboxamide, PHOSPHATE ION, Protease | Authors: | Nalam, M.N.L, Schiffer, C.A. | Deposit date: | 2009-03-05 | Release date: | 2010-03-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. J.Virol., 84, 2010
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2HBA
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![BU of 2hba by Molmil](/molmil-images/mine/2hba) | Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9) K12M | Descriptor: | 50S ribosomal protein L9, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P. | Deposit date: | 2006-06-14 | Release date: | 2007-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Energetically significant networks of coupled interactions within an unfolded protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3GIM
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![BU of 3gim by Molmil](/molmil-images/mine/3gim) | Dpo4 extension ternary complex with oxoG(anti)-G(syn) pair | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DDG))-3', ... | Authors: | Rechkoblit, O, Malinina, L, Patel, D.J. | Deposit date: | 2009-03-05 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure, 17, 2009
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2OZ5
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![BU of 2oz5 by Molmil](/molmil-images/mine/2oz5) | Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS | Descriptor: | Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID | Authors: | Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2007-02-23 | Release date: | 2007-05-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB. Structure, 15, 2007
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4JAY
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![BU of 4jay by Molmil](/molmil-images/mine/4jay) | Crystal structure of P. aeruginosa MurB in complex with NADP+ | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Chen, M.W, Lohkamp, B, Schnell, R, Lescar, J, Schneider, G. | Deposit date: | 2013-02-19 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates. Plos One, 8, 2013
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4NHX
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![BU of 4nhx by Molmil](/molmil-images/mine/4nhx) | Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with N-oxalylglycine (NOG) | Descriptor: | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Horita, S, McDonough, M.A, Schofield, C.J. | Deposit date: | 2013-11-05 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
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3FZD
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![BU of 3fzd by Molmil](/molmil-images/mine/3fzd) | Mutation of Asn28 disrupts the enzymatic activity and dimerization of SARS 3CLpro | Descriptor: | 3C-like proteinase | Authors: | Barrila, J, Gabelli, S, Bacha, U, Amzel, L.M, Freire, E. | Deposit date: | 2009-01-25 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) . Biochemistry, 49, 2010
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2P98
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![BU of 2p98 by Molmil](/molmil-images/mine/2p98) | E. coli methionine aminopeptidase monometalated with inhibitor YE7 | Descriptor: | IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE, MANGANESE (II) ION, Methionine aminopeptidase, ... | Authors: | Ye, Q. | Deposit date: | 2007-03-24 | Release date: | 2007-11-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis. J.Med.Chem., 50, 2007
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4NDF
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![BU of 4ndf by Molmil](/molmil-images/mine/4ndf) | Human Aprataxin (Aptx) bound to RNA-DNA, AMP, and Zn - product complex | Descriptor: | 5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3', 5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3', ADENOSINE MONOPHOSPHATE, ... | Authors: | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | Deposit date: | 2013-10-26 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.944 Å) | Cite: | Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity. Nature, 506, 2013
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4NDV
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3FYJ
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![BU of 3fyj by Molmil](/molmil-images/mine/3fyj) | Crystal structure of an optimzied benzothiophene inhibitor bound to MAPKAP Kinase-2 (MK-2) | Descriptor: | (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, MAP kinase-activated protein kinase 2 | Authors: | Kurumbail, R.G, Caspers, N. | Deposit date: | 2009-01-22 | Release date: | 2009-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg.Med.Chem.Lett., 19, 2009
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4JFR
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![BU of 4jfr by Molmil](/molmil-images/mine/4jfr) | Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with carbamoyl phosphate | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Ornithine carbamoyltransferase, ... | Authors: | Shabalin, I.G, Winsor, J, Grimshaw, S, Osinski, T, Bajor, J, Chordia, M.D, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-02-28 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis to be published
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2H8K
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![BU of 2h8k by Molmil](/molmil-images/mine/2h8k) | Human Sulfotranferase SULT1C3 in complex with PAP | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, SULT1C3 splice variant d | Authors: | Tempel, W, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-07 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and chemical profiling of the human cytosolic sulfotransferases. Plos Biol., 5, 2007
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4JH8
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![BU of 4jh8 by Molmil](/molmil-images/mine/4jh8) | Crystal Structure of FosB from Bacillus cereus with Zinc and L-Cysteine-Fosfomycin Ternary Complex | Descriptor: | CYSTEINE, FOSFOMYCIN, GLYCEROL, ... | Authors: | Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N. | Deposit date: | 2013-03-04 | Release date: | 2013-10-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus. Biochemistry, 52, 2013
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4JTF
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![BU of 4jtf by Molmil](/molmil-images/mine/4jtf) | Crystal structure of F114R mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... | Authors: | Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. | Deposit date: | 2013-03-23 | Release date: | 2013-06-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52, 2013
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3G19
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![BU of 3g19 by Molmil](/molmil-images/mine/3g19) | The structure of the Caulobacter crescentus clpS protease adaptor protein in complex with LLL tripeptide | Descriptor: | ATP-dependent Clp protease adapter protein clpS, LLL tripeptide | Authors: | Baker, T.A, Roman-Hernandez, G, Sauer, R.T, Grant, R.A. | Deposit date: | 2009-01-29 | Release date: | 2009-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Molecular basis of substrate selection by the N-end rule adaptor protein ClpS. Proc.Natl.Acad.Sci.USA, 106, 2009
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3G27
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![BU of 3g27 by Molmil](/molmil-images/mine/3g27) | Structure of a putative bacteriophage protein from Escherichia coli str. K-12 substr. MG1655 | Descriptor: | 1,2-ETHANEDIOL, 82 prophage-derived uncharacterized protein ybcO, CALCIUM ION, ... | Authors: | Cuff, M.E, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-01-30 | Release date: | 2009-03-24 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a putative bacteriophage protein from Escherichia coli str. K-12 substr. MG1655 TO BE PUBLISHED
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2PC2
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![BU of 2pc2 by Molmil](/molmil-images/mine/2pc2) | Lysozyme Cocrystallized with Tris-dipicolinate Eu complex | Descriptor: | CHLORIDE ION, EUROPIUM ION, Lysozyme C, ... | Authors: | Pompidor, G, Vicat, J, Kahn, R. | Deposit date: | 2007-03-29 | Release date: | 2008-04-01 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.538 Å) | Cite: | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction Acta Crystallogr.,Sect.D, 66, 2010
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2P6A
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![BU of 2p6a by Molmil](/molmil-images/mine/2p6a) | The structure of the Activin:Follistatin 315 complex | Descriptor: | Follistatin, Inhibin beta A chain, probable fragment of follistatin | Authors: | Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S. | Deposit date: | 2007-03-16 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions. J.Biol.Chem., 282, 2007
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3G2E
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![BU of 3g2e by Molmil](/molmil-images/mine/3g2e) | Structure of putative OORC subunit of 2-oxoglutarate:acceptor oxidoreductase from Campylobacter jejuni | Descriptor: | GLYCEROL, OORC subunit of 2-oxoglutarate:acceptor oxidoreductase | Authors: | Ramagopal, U.A, Toro, R, Miller, S, Gilmore, M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-01-31 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of putative OORC subunit of 2-oxoglutarate:acceptor oxidoreductase from
Campylobacter jejuni To be Published
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