4L76
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![BU of 4l76 by Molmil](/molmil-images/mine/4l76) | Ca2+-bound E212Q mutant MthK RCK domain | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK, SODIUM ION | Authors: | Smith, F.J, Rothberg, B.S. | Deposit date: | 2013-06-13 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.992 Å) | Cite: | Structural basis of allosteric interactions among Ca(2+)-binding sites in a K(+) channel RCK domain. Nat Commun, 4, 2013
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3M70
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4JWR
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4L9Q
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![BU of 4l9q by Molmil](/molmil-images/mine/4l9q) | X-ray study of human serum albumin complexed with teniposide | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, SERUM ALBUMIN | Authors: | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | Deposit date: | 2013-06-18 | Release date: | 2013-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830, 2013
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4JO0
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![BU of 4jo0 by Molmil](/molmil-images/mine/4jo0) | Crystal Structure of CmlA, a diiron beta-hydroxylase from Streptomyces venezuelae | Descriptor: | ACETATE ION, CmlA, FE (III) ION, ... | Authors: | Knoot, C.J, Makris, T.M, Wilmot, C.M, Lipscomb, J.D. | Deposit date: | 2013-03-16 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure of a Dinuclear Iron Cluster-Containing beta-Hydroxylase Active in Antibiotic Biosynthesis. Biochemistry, 52, 2013
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2NO2
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4LAO
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![BU of 4lao by Molmil](/molmil-images/mine/4lao) | Crystal structure of Cordyceps militaris IDCase H195A mutant (Zn) | Descriptor: | Cordyceps militaris IDCase, DI(HYDROXYETHYL)ETHER, ZINC ION | Authors: | Xu, S, Li, W, Zhu, J, Ding, J. | Deposit date: | 2013-06-20 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
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2IIC
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2NQO
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![BU of 2nqo by Molmil](/molmil-images/mine/2nqo) | Crystal Structure of Helicobacter pylori gamma-Glutamyltranspeptidase | Descriptor: | Gamma-glutamyltranspeptidase | Authors: | Boanca, G, Sand, A, Okada, T, Suzuki, H, Kumagai, H, Fukuyama, K, Barycki, J.J. | Deposit date: | 2006-10-31 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Autoprocessing of Helicobacter pylori gamma-glutamyltranspeptidase leads to the formation of a threonine-threonine catalytic dyad. J.Biol.Chem., 282, 2007
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5MZ6
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![BU of 5mz6 by Molmil](/molmil-images/mine/5mz6) | Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution | Descriptor: | Interactor of FizzY protein, SEParase | Authors: | Boland, A, Martin, T.G, Zhang, Z, Yang, J, Bai, X.C, Chang, L, Scheres, S.H.W, Barford, D. | Deposit date: | 2017-01-31 | Release date: | 2017-03-08 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution. Nat. Struct. Mol. Biol., 24, 2017
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3G0Q
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![BU of 3g0q by Molmil](/molmil-images/mine/3g0q) | Crystal Structure of MutY bound to its inhibitor DNA | Descriptor: | 5'-D(*AP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*AP*GP*TP*CP*TP*T)-3', A/G-specific adenine glycosylase, ... | Authors: | Lee, S, Verdine, G.L. | Deposit date: | 2009-01-28 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc.Natl.Acad.Sci.Usa, 106, 2009
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3MDI
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3FXM
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![BU of 3fxm by Molmil](/molmil-images/mine/3fxm) | Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Citrate at 10 mM of Mn2+ | Descriptor: | CITRATE ANION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | Deposit date: | 2009-01-21 | Release date: | 2010-01-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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3MRO
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![BU of 3mro by Molmil](/molmil-images/mine/3mro) | Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant | Descriptor: | 10-meric peptide from Melanoma antigen recognized by T-cells 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | Deposit date: | 2010-04-29 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
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3MG4
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![BU of 3mg4 by Molmil](/molmil-images/mine/3mg4) | Structure of yeast 20S proteasome with Compound 1 | Descriptor: | (2S)-2-amino-N-[(1S)-1-({(1S)-1-[(4-methylbenzyl)carbamoyl]-3-phenylpropyl}carbamoyl)-3-phenylpropyl]-4-phenylbutanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... | Authors: | Sintchak, M.D. | Deposit date: | 2010-04-05 | Release date: | 2011-04-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem.J., 430, 2010
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3G2Z
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4L78
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![BU of 4l78 by Molmil](/molmil-images/mine/4l78) | Xenon Trapping and Statistical Coupling Analysis Uncover Regions Important for Structure and Function of Multidomain Protein StPurL | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. | Deposit date: | 2013-06-13 | Release date: | 2013-12-11 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
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4LF8
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![BU of 4lf8 by Molmil](/molmil-images/mine/4lf8) | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, PAROMOMYCIN, ... | Authors: | Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-06-26 | Release date: | 2014-07-02 | Method: | X-RAY DIFFRACTION (3.1484 Å) | Cite: | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus to be published, 2013
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3FYN
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![BU of 3fyn by Molmil](/molmil-images/mine/3fyn) | Crystal structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3 | Descriptor: | ACETATE ION, Integron gene cassette protein HFX_CASS3, MAGNESIUM ION | Authors: | Sureshan, V, Deshpande, C.N, Harrop, S.J, Kudritska, M, Koenig, J.E, Evdokimova, E, Osipiuk, J, Edwards, A.M, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-01-22 | Release date: | 2009-02-10 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Structure from the mobile metagenome of Cole Harbour Salt Marsh: Integron Cassette Protein HFX_CASS3 To be Published
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4J9U
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![BU of 4j9u by Molmil](/molmil-images/mine/4j9u) | Crystal Structure of the TrkH/TrkA potassium transport complex | Descriptor: | HEXATANTALUM DODECABROMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ... | Authors: | Cao, Y, Jin, X, Huang, H, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2013-02-17 | Release date: | 2013-04-03 | Last modified: | 2013-05-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Gating of the TrkH ion channel by its associated RCK protein TrkA. Nature, 496, 2013
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4JE4
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![BU of 4je4 by Molmil](/molmil-images/mine/4je4) | Crystal Structure of Monobody NSa1/SHP2 N-SH2 Domain Complex | Descriptor: | Monobody NSa1, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Sha, F, Koide, S. | Deposit date: | 2013-02-26 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains. Proc.Natl.Acad.Sci.USA, 110, 2013
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4JEO
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3GI6
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![BU of 3gi6 by Molmil](/molmil-images/mine/3gi6) | Crystal structure of protease inhibitor, AD78 in complex with wild type HIV-1 protease | Descriptor: | (5S)-N-[(1S,2R)-2-Hydroxy-3-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)propyl]-2-oxo-3-[3-(trif luoromethyl)phenyl]-5-oxazolidinecarboxamide, PHOSPHATE ION, Protease | Authors: | Nalam, M.N.L, Schiffer, C.A. | Deposit date: | 2009-03-05 | Release date: | 2010-03-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. J.Virol., 84, 2010
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4LJ3
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![BU of 4lj3 by Molmil](/molmil-images/mine/4lj3) | Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++ | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Cyclic di-GMP phosphodiesterase YahA, ... | Authors: | Sundriyal, A, Schirmer, T. | Deposit date: | 2013-07-04 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP. J.Biol.Chem., 289, 2014
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3MLU
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![BU of 3mlu by Molmil](/molmil-images/mine/3mlu) | Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a ZAM18 V3 peptide | Descriptor: | HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain | Authors: | Kong, X.-P. | Deposit date: | 2010-04-18 | Release date: | 2010-07-14 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol., 17, 2010
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