6TZE
| Human CstF-64 RRM mutant - D50A | Descriptor: | Cleavage stimulation factor subunit 2 | Authors: | Latham, M.P, Masoumzadeh, E. | Deposit date: | 2019-08-12 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans. Nucleic Acids Res., 48, 2020
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7TZ3
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3CZZ
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6DUU
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6ALY
| Solution structure of yeast Med15 ABD2 residues 277-368 | Descriptor: | Mediator of RNA polymerase II transcription subunit 15 | Authors: | Tuttle, L.M, Pacheco, D, Warfield, L, Hahn, S, Klevit, R.E. | Deposit date: | 2017-08-08 | Release date: | 2018-03-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex. Cell Rep, 22, 2018
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6D2H
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7T1P
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7T6G
| Truncated Ac-AIP-2 | Descriptor: | Truncated Ac-AIP-2 | Authors: | Daly, N.L, Cobos, C. | Deposit date: | 2021-12-13 | Release date: | 2022-10-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells. Front Med (Lausanne), 9, 2022
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4B6U
| Solution structure of eIF4E3 in complex with m7GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 | Authors: | Osborne, M.J, Volpon, L, Kornblatt, J.A, Culkjovic-Kraljcic, B, Baguet, A, Borden, K.L.B. | Deposit date: | 2012-08-15 | Release date: | 2013-03-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Eif4E3 Acts as a Tumor Suppressor by Utilizing an Atypical Mode of Methyl-7-Guanosine CAP Recognition Proc.Natl.Acad.Sci.USA, 110, 2013
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5XF0
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8P7G
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5Z26
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5Z2O
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3CS9
| Human ABL kinase in complex with nilotinib | Descriptor: | Nilotinib, Proto-oncogene tyrosine-protein kinase ABL1 | Authors: | Cowan-Jacob, S.W, Fendrich, G, Manley, P, Liebetanz, J, Fabbro, D. | Deposit date: | 2008-04-09 | Release date: | 2008-04-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl Cancer Cell, 7, 2005
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6C2U
| Solution structure of a phosphate-loop protein | Descriptor: | phosphate-loop protein | Authors: | Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G. | Deposit date: | 2018-01-09 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Simple yet functional phosphate-loop proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7JX7
| BRD2-BD2 in complex with a diacetylated-H2A.Z peptide | Descriptor: | Bromodomain-containing protein 2, Diacetylated-H2A.Z peptide | Authors: | Patel, K, Low, J.K.K, Mackay, J.P, Solomon, P.D. | Deposit date: | 2020-08-26 | Release date: | 2020-12-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The bromodomains of BET family proteins can recognize diacetylated histone H2A.Z. Protein Sci., 30, 2021
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6XOR
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6XTT
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6Y94
| Ca2+-bound Calmodulin mutant N53I | Descriptor: | CALCIUM ION, Calmodulin | Authors: | Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | Deposit date: | 2020-03-06 | Release date: | 2020-04-29 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. J.Biol.Chem., 295, 2020
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6Y1Q
| Cortistatin analog with improved immunoregulatory activity | Descriptor: | Analog 5, OCTANOIC ACID (CAPRYLIC ACID) | Authors: | Rol, A. | Deposit date: | 2020-02-13 | Release date: | 2021-01-27 | Last modified: | 2024-07-10 | Method: | SOLUTION NMR | Cite: | Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease. Nat Commun, 12, 2021
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5XND
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6Y1H
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5XHT
| The PHD finger of human Kiaa1045 protein | Descriptor: | PHD finger protein 24, ZINC ION | Authors: | Miyamoto, K. | Deposit date: | 2017-04-24 | Release date: | 2018-05-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the PHD finger from the human KIAA1045 protein Protein Sci., 27, 2018
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6CO4
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6CPI
| Solution structure of SH3 domain from Shank1 | Descriptor: | SH3 and multiple ankyrin repeat domains protein 1 | Authors: | Ishida, H, Vogel, H.J. | Deposit date: | 2018-03-13 | Release date: | 2018-08-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels. FEBS Lett., 592, 2018
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