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8YB5
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BU of 8yb5 by Molmil
SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry)
Descriptor: Non-structural protein 4, Papain-like protease nsp3
Authors:Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
Deposit date:2024-02-11
Release date:2024-06-19
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
8YB4
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BU of 8yb4 by Molmil
Pfr conformer of Arabidopsis thaliana phytochrome B in complex with phytochrome-interacting factor 6
Descriptor: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, phytochrome B, phytochrome-interacting factor 6
Authors:Wang, Z, Wang, W, Zhao, D, Song, Y, Xu, B, Zhao, J, Wang, J.
Deposit date:2024-02-11
Release date:2024-10-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor.
Cell, 187, 2024
8YB6
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BU of 8yb6 by Molmil
Type I-EHNH Cascade complex
Descriptor: 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ...
Authors:Li, Z.
Deposit date:2024-02-11
Release date:2024-07-31
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems.
Mol.Cell, 84, 2024
8VZ8
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BU of 8vz8 by Molmil
Crystal structure of mouse MAIT M2B TCR-MR1-5-OP-RU complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ciacchi, L, Rossjohn, J, Awad, W.
Deposit date:2024-02-11
Release date:2024-04-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
J.Biol.Chem., 300, 2024
8VZ9
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Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ciacchi, L, Rossjohn, J, Awad, W.
Deposit date:2024-02-11
Release date:2024-04-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
J.Biol.Chem., 300, 2024
8VZM
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BU of 8vzm by Molmil
DNA Ligase 1 captured with pre-step 3 ligation at the rA:T nicksite
Descriptor: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2024-02-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8VZL
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BU of 8vzl by Molmil
DNA Ligase 1 captured with pre-step 3 ligation at the rG:C nicksite
Descriptor: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2024-02-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8YAX
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BU of 8yax by Molmil
SARS-CoV-2 DMV nsp3-4 pore complex (full-pore)
Descriptor: Non-structural protein 4, Papain-like protease nsp3
Authors:Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
Deposit date:2024-02-10
Release date:2024-06-19
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
8RYT
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BU of 8ryt by Molmil
Structural characterization of Thogoto Virus nucleoprotein provides insights into RNA encapsidation and assembly
Descriptor: Nucleoprotein
Authors:Roske, Y, Mikirtumov, V, Daumke, O, Kudryashev, M, Dick, A.
Deposit date:2024-02-09
Release date:2024-06-19
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Structure, 32, 2024
8RYN
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BU of 8ryn by Molmil
Structure of S2 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide
Descriptor: Beta-2-microglobulin, ELFSYLIEK peptide, MHC class I antigen, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of S2 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide
To Be Published
8RYQ
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BU of 8ryq by Molmil
Structure of S8-9F3 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide
Descriptor: Beta-2-microglobulin, ELFSYLIEK peptide, MHC class I antigen, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of S8-9F3 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide
To Be Published
8RYM
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BU of 8rym by Molmil
Structure of S2 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
Descriptor: Beta-2-microglobulin, ELFSYLIEK peptide, HLA class I histocompatibility antigen, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structure of S2 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
To Be Published
8RYO
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BU of 8ryo by Molmil
Structure of S2-198 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
Descriptor: 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Beta-2-microglobulin, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of S2-198 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
To Be Published
8RYP
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BU of 8ryp by Molmil
Structure of S8 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, ELFSYLIEK peptide, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure of S8 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
To Be Published
8YAN
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BU of 8yan by Molmil
Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound
Descriptor: RNA (33-MER), ~{N},~{N}-dimethyl-2-[(1-methyl-9~{H}-pyrido[3,4-b]indol-7-yl)oxy]ethanamine
Authors:Numata, T, Schneekloth, J.S.
Deposit date:2024-02-09
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.
Biorxiv, 2024
8YAM
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BU of 8yam by Molmil
Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound
Descriptor: 2-[2-(dimethylamino)ethoxy]xanthen-9-one, RNA (33-MER)
Authors:Numata, T, Parmar, S, Schneekloth, J.S.
Deposit date:2024-02-09
Release date:2024-09-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.
Biorxiv, 2024
8YAL
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BU of 8yal by Molmil
ATAT-2 bound K40Q MEC-12/MEC-7 microtubule
Descriptor: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase 2, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Lam, W.H, Yu, D, Zhai, Y, Ti, S.
Deposit date:2024-02-09
Release date:2024-11-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets.
Nat.Struct.Mol.Biol., 2024
8RYS
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BU of 8rys by Molmil
Human IL-1beta, unliganded
Descriptor: Interleukin-1 beta, SULFATE ION
Authors:Rondeau, J.-M, Lehmann, S.
Deposit date:2024-02-09
Release date:2024-03-06
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches.
J.Med.Chem., 67, 2024
8RYK
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BU of 8ryk by Molmil
IL-1beta in complex with macrocyclic peptide hit
Descriptor: Interleukin-1 beta, Macrocyclic peptide
Authors:Rondeau, J.-M, Lehmann, S.
Deposit date:2024-02-09
Release date:2024-05-22
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches.
J.Med.Chem., 67, 2024
8YAJ
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BU of 8yaj by Molmil
ATAT-2 bound MEC-12/MEC-7 microtubule without acetyl-CoA
Descriptor: Alpha-tubulin N-acetyltransferase 2, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Lam, W.H, Yu, D, Zhai, Y, Ti, S.
Deposit date:2024-02-09
Release date:2024-11-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets.
Nat.Struct.Mol.Biol., 2024
8YAR
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BU of 8yar by Molmil
ATAT-2 bound K40R MEC-12/MEC-7 microtubule
Descriptor: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase 2, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Lam, W.H, Yu, D, Zhai, Y, Ti, S.
Deposit date:2024-02-09
Release date:2024-11-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets.
Nat.Struct.Mol.Biol., 2024
8RXX
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BU of 8rxx by Molmil
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN
Descriptor: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ...
Authors:Rajan, K.S, Yonath, A.
Deposit date:2024-02-08
Release date:2024-05-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Cell Rep, 43, 2024
8VYL
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BU of 8vyl by Molmil
The structure of Human Hemoglobin in Complex with Nanobody BtNbE11
Descriptor: ACETYL GROUP, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Grinter, R, Binks, S, Fox, D.
Deposit date:2024-02-08
Release date:2024-07-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The structure of a haemoglobin-nanobody complex reveals human beta-subunit-specific interactions.
Febs Lett., 598, 2024
8VYD
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BU of 8vyd by Molmil
A novel synthase generates m4(2)C to stabilize the archaeal ribosome
Descriptor: SAM-dependent methyltransferase, UPF0020 family, SODIUM ION
Authors:Ho, P.S, Santangelo, T.J, Fluke, K.
Deposit date:2024-02-08
Release date:2024-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A novel synthase generates m4(2)C to stabilize the archaeal ribosome
To Be Published
8YAA
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BU of 8yaa by Molmil
Cryo-EM structure of MIK2-SCOOP12-BAK1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, ...
Authors:Jia, F.S, Xiao, Y, Chai, J.J.
Deposit date:2024-02-08
Release date:2024-10-30
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structure of MIK2-SCOOP12-BAK1
To Be Published

227344

数据于2024-11-13公开中

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