8YAN

Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound

This is a non-PDB format compatible entry.

Summary for 8YAN

• Entry DOI: 10.2210/pdb8yan/pdb
• Descriptor: RNA (33-MER), ~{N},~{N}-dimethyl-2-[(1-methyl-9~{H}-pyrido[3,4-b]indol-7-yl)oxy]ethanamine (3 entities in total)
• Functional Keywords: riboswitch, rna
• Biological source: Caldanaerobacter subterraneus subsp. tengcongensis
• Total number of polymer chains: 1
• Total formula weight: 10493.45

Authors

Numata, T.,Schneekloth, J.S. (deposition date: 2024-02-09, release date: 2024-09-11)

• Primary citation: Parmar, S.,Bume, D.D.,Conelly, C.,Boer, R.,Prestwood, P.R.,Wang, Z.,Labuhn, H.,Sinnadurai, K.,Feri, A.,Ouellet, J.,Homan, P.,Numata, T.,Schneekloth Jr., J.S.; Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.; Biorxiv, 2024; PubMed: 38903087; DOI: 10.1101/2024.02.23.581746

Experimental method

X-RAY DIFFRACTION (2.25 Å)