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6VPL
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BU of 6vpl by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 with C290 disulfide bonded to compound 7-80, and in complex with AMP-PNP
Descriptor: GLYCEROL, MAGNESIUM ION, MALONIC ACID, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
6XZ6
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BU of 6xz6 by Molmil
Structure of the trypanosome brucei factor H receptor bound to domain D5 of bovine factor H
Descriptor: Complement factor H, GARP domain-containing protein
Authors:Macleod, O.J.S, Carrington, M, Higgins, M.K.
Deposit date:2020-02-02
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Nat Commun, 11, 2020
6VP6
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BU of 6vp6 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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BU of 6vp7 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
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BU of 6vp8 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6XYW
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BU of 6xyw by Molmil
Structure of the plant mitochondrial ribosome
Descriptor: 28S ribosomal S34 protein, 3-hydroxyisobutyryl-CoA hydrolase-like protein 2, mitochondrial, ...
Authors:Soufari, H, Waltz, F, Bochler, A, Giege, P, Hashem, Y.
Deposit date:2020-01-31
Release date:2020-04-15
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Cryo-EM structure of the RNA-rich plant mitochondrial ribosome.
Nat.Plants, 6, 2020
6XYK
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BU of 6xyk by Molmil
Crystal structure of bovine trypsin at room temperature.
Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
Authors:Jensen, M.
Deposit date:2020-01-30
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.50000036 Å)
Cite:Femtosecond structure of bovine trypsin at room temperature
To Be Published
6XYG
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BU of 6xyg by Molmil
Femtosecond structure of bovine trypsin at room temperature
Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
Authors:Jensen, M.
Deposit date:2020-01-30
Release date:2021-02-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.50000238 Å)
Cite:High-resolution macromolecular crystallography at the FemtoMAX beamline with time-over-threshold photon detection
J.Synchrotron Radiat., 2021
6LUQ
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BU of 6luq by Molmil
Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands
Descriptor: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one, OLEIC ACID, chimera of D(2) dopamine receptor and Endolysin
Authors:Fan, L, Tan, L, Chen, Z, Qi, J, Nie, F, Luo, Z, Cheng, J, Wang, S.
Deposit date:2020-01-30
Release date:2020-03-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Haloperidol bound D2dopamine receptor structure inspired the discovery of subtype selective ligands.
Nat Commun, 11, 2020
6LUR
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BU of 6lur by Molmil
Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder
Descriptor: 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one, Thioredoxin 1,Poly(U)-binding-splicing factor PUF60
Authors:Takahashi, M, Hanzawa, H.
Deposit date:2020-01-30
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery.
J.Biomol.Nmr, 74, 2020
6VOG
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BU of 6vog by Molmil
Chloroplast ATP synthase (O2, CF1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOE
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BU of 6voe by Molmil
HIV-1 wild type protease with GRL-019-17A, a tricyclic cyclohexane fused tetrahydrofuranofuran (CHf-THF) derivative as the P2 ligand and a aminobenzothiazole(Abt)-based P2'-ligand
Descriptor: (1S,3aR,5S,6R,7aS)-octahydro-1,6-epoxy-2-benzofuran-5-yl {(2S,3R)-3-hydroxy-4-[(2-methylpropyl)({2-[(propan-2-yl)amino]-1,3-benzoxazol-6-yl}sulfonyl)amino]-1-phenylbutan-2-yl}carbamate, ACETATE ION, CHLORIDE ION, ...
Authors:Wang, Y.-F, Agniswamy, J, Weber, I.T.
Deposit date:2020-01-30
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies.
J.Med.Chem., 63, 2020
6VOK
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BU of 6vok by Molmil
Chloroplast ATP synthase (R3, CF1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOI
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BU of 6voi by Molmil
Chloroplast ATP synthase (O1, CF1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOL
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BU of 6vol by Molmil
Chloroplast ATP synthase (R2, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VON
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BU of 6von by Molmil
Chloroplast ATP synthase (R1, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOH
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BU of 6voh by Molmil
Chloroplast ATP synthase (O1, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOF
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BU of 6vof by Molmil
Chloroplast ATP synthase (O2, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (4.51 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOD
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BU of 6vod by Molmil
HIV-1 wild type protease with GRL-052-16A, a tricyclic cyclohexane fused tetrahydrofuranofuran (CHf-THF) derivative as the P2 ligand
Descriptor: (1R,3aS,5R,6S,7aR)-octahydro-1,6-epoxy-2-benzofuran-5-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, FORMIC ACID, ...
Authors:Wang, Y.-F, Agniswamy, J, Weber, I.T.
Deposit date:2020-01-30
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies.
J.Med.Chem., 63, 2020
6VOJ
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BU of 6voj by Molmil
Chloroplast ATP synthase (R3, CF1FO)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOM
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BU of 6vom by Molmil
Chloroplast ATP synthase (R2, CF1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VOA
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BU of 6voa by Molmil
Cryo-EM structure of the BBSome-ARL6 complex
Descriptor: ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ...
Authors:Yang, S, Walz, T, Nachury, M.V.
Deposit date:2020-01-30
Release date:2020-06-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Elife, 9, 2020
6VOO
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BU of 6voo by Molmil
Chloroplast ATP synthase (R1, CF1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
Authors:Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
Deposit date:2020-01-30
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VN7
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BU of 6vn7 by Molmil
Cryo-EM structure of an activated VIP1 receptor-G protein complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Duan, J, Shen, D.-D, Zhou, X.E, Liu, Q.-F, Zhuang, Y.-W, Zhang, H.-B, Xu, P.-Y, Ma, S.-S, He, X.-H, Melcher, K, Zhang, Y, Xu, H.E, Yi, J.
Deposit date:2020-01-29
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy.
Nat Commun, 11, 2020
6VNO
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BU of 6vno by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-01-29
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020

222415

数据于2024-07-10公开中

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