6KQF
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt | Descriptor: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Zhang, Y, Li, L, Ebright, R.H. | Deposit date: | 2019-08-17 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6L74
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Zhang, Y, Li, L, Ebright, R.H. | Deposit date: | 2019-10-31 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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4MFR
| Crystal structure of Mycobacterium tuberculosis CarD | Descriptor: | GLYCEROL, IODIDE ION, RNA polymerase-binding transcription factor CarD, ... | Authors: | Kaur, G, Thakur, K.G. | Deposit date: | 2013-08-28 | Release date: | 2013-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis CarD, an essential RNA polymerase binding protein, reveals a quasidomain-swapped dimeric structural architecture. Proteins, 82, 2014
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1U09
| Footand Mouth Disease Virus RNA-dependent RNA polymerase | Descriptor: | polyprotein | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-13 | Release date: | 2004-08-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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9JA1
| The RNA polymerase II elongation complex from Saccharomyces cerevisiae | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*CP*TP*CP*CP*TP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*T)-3'), DNA (5'-D(P*TP*GP*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*C)-3'), ... | Authors: | Yi, G, Ma, J, Zhang, P. | Deposit date: | 2024-08-23 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | The RNA polymerase II elongation complex from Saccharomyces cerevisiae To Be Published
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2DK8
| Solution structure of rpc34 subunit in RNA polymerase III from mouse | Descriptor: | DNA-directed RNA polymerase III 39 kDa polypeptide | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-06 | Release date: | 2006-10-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of rpc34 subunit in RNA polymerase III from mouse To be Published
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1KU2
| Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2 to 3.1 | Descriptor: | SULFATE ION, sigma factor sigA | Authors: | Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A. | Deposit date: | 2002-01-21 | Release date: | 2002-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the bacterial RNA polymerase promoter specificity sigma subunit. Mol.Cell, 9, 2002
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8Q3I
| Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State I | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Koval, T, Krasny, L, Dohnalek, J, Kouba, T. | Deposit date: | 2023-08-04 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Molecular insights into RNA polymerase recycling by mycobacterial HelD To Be Published
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7OKX
| Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | Deposit date: | 2021-05-18 | Release date: | 2021-07-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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7OKY
| Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | Deposit date: | 2021-05-18 | Release date: | 2021-07-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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7OL0
| Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | Deposit date: | 2021-05-18 | Release date: | 2021-07-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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2DK5
| Solution structure of Winged-Helix domain in RNA polymerase III 39KDa polypeptide | Descriptor: | DNA-directed RNA polymerase III 39 kDa polypeptide | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-06 | Release date: | 2006-10-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of Winged-Helix domain in RNA polymerase III 39KDa polypeptide To be Published
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6TQO
| rrn anti-termination complex | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6GYM
| Structure of a yeast closed complex with distorted DNA (CCdist) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6GYK
| Structure of a yeast closed complex (core CC1) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6GYL
| Structure of a yeast closed complex with distorted DNA (core CCdist) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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8FIZ
| Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | Deposit date: | 2022-12-18 | Release date: | 2023-03-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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4XLR
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8CRO
| Cryo-EM structure of Pyrococcus furiosus transcription elongation complex | Descriptor: | DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... | Authors: | Tarau, D.M, Grunberger, F, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | Deposit date: | 2023-03-08 | Release date: | 2024-04-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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8UHG
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8UI0
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7MEI
| Composite structure of EC+EC | Descriptor: | DNA (74-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Yang, C, Murakami, K. | Deposit date: | 2021-04-06 | Release date: | 2022-03-02 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
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8UHA
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7MK9
| Complex structure of trailing EC of EC+EC (trailing EC-focused) | Descriptor: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Yang, C, Murakami, K. | Deposit date: | 2021-04-22 | Release date: | 2022-04-27 | Last modified: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
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7MKA
| Structure of EC+EC (leading EC-focused) | Descriptor: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Yang, C, Murakami, K. | Deposit date: | 2021-04-22 | Release date: | 2022-04-27 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
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