PDB: 54296 resultsInfo pagesStatus searchChemie searchBIRD

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7N7J	Crystal Structure of PI5P4KIIAlpha complex with AMPPNP Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ... Authors: Chen, S, Ha, Y. Deposit date: 2021-06-10 Release date: 2021-06-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
4JYZ	Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (72-MER), ... Authors: Perona, J.J, Rodriguez-Hernandez, A. Deposit date: 2013-04-01 Release date: 2013-05-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position. J.Mol.Biol., 425, 2013
7N7K	Crystal Structure of PI5P4KIIAlpha complex with AMPPNP Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ... Authors: Chen, S, Ha, Y. Deposit date: 2021-06-10 Release date: 2021-06-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
5LA3	[FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant E279A Descriptor: FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, Iron hydrogenase 1, ... Authors: Duan, J, Esselborn, J, Hofmann, E, Winkler, M, Happe, T. Deposit date: 2016-06-13 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Accumulating the hydride state in the catalytic cycle of [FeFe]-hydrogenases. Nat Commun, 8, 2017
2RMR	Solution structure of mSin3A PAH1 domain Descriptor: Paired amphipathic helix protein Sin3a Authors: Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. Deposit date: 2007-11-14 Release date: 2008-01-22 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor J.Mol.Biol., 375, 2007
6SVA	Multicrystal structure of equine Haemoglobin at room temperature using a multilayer monochromator. Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE Authors: Sandy, J, Sanchez-Weatherby, J, Mikolajek, H, Lewis, G, Angus, R. Deposit date: 2019-09-18 Release date: 2019-11-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Protein-to-structure pipeline for ambient-temperature crystallography at VMXi Iucrj, 2023
6SLC	Mutations in SsgB correlate to longitudinal cell division during sporulation of Streptomyces coelicolor Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PHOSPHATE ION, ... Authors: Xiao, X.S, Willemse, J. Deposit date: 2019-08-19 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces . Open Biology, 11, 2021
4JXZ	Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ... Authors: Perona, J.J, Rodriguez-Hernandez, A. Deposit date: 2013-03-28 Release date: 2013-05-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position. J.Mol.Biol., 425, 2013
6HWN	Structure of Thermus thermophilus ClpP in complex with a tripeptide. Descriptor: ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, Unknown tripeptide Authors: Felix, J, Schanda, P, Fraga, H, Morlot, C. Deposit date: 2018-10-12 Release date: 2019-09-18 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors. Sci Adv, 5, 2019
5OFM	Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1H-indole Descriptor: 1-methylindol-5-amine, D-3-phosphoglycerate dehydrogenase Authors: Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. Deposit date: 2017-07-11 Release date: 2017-08-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1H-indole To be published
5L3M	D11 bound [S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2024-10-23 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3L	D11 bound IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2024-11-06 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3N	D11 bound [N29, S39_PQ]-IGF-II Descriptor: Insulin-like growth factor II Authors: Hexnerova, R. Deposit date: 2016-05-23 Release date: 2016-08-10 Last modified: 2024-11-06 Method: SOLUTION NMR Cite: Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5LFR	Crystal structure of glycosylated Myelin-associated glycoprotein (MAG) Ig1-3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Myelin-associated glycoprotein, ... Authors: Pronker, M.F, Janssen, B.J.C. Deposit date: 2016-07-04 Release date: 2016-12-14 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun, 7, 2016
2VKL	X-ray crystal structure of the intracellular Chorismate mutase from Mycobactrerium Tuberculosis in complex with malate Descriptor: D-MALATE, RV0948C/MT0975 Authors: Okvist, M, Roderer, K, Sasso, S, Kast, P, Krengel, U. Deposit date: 2007-12-20 Release date: 2008-01-15 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner. Embo J., 28, 2009
5LFV	Crystal structure of glycosylated Myelin-associated glycoprotein (MAG) Ig1-3 with soaked trisaccharide ligand Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Myelin-associated glycoprotein, ... Authors: Pronker, M.F, Janssen, B.J.C. Deposit date: 2016-07-04 Release date: 2016-12-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun, 7, 2016
7LGK	Crystal structure of soluble guanylate cyclase activator runcaciguat (BAY 1101042) bound to nostoc H-NOX domain Descriptor: CHLORIDE ION, GLYCEROL, H-NOX domain protein, ... Authors: van den Akker, F, Kumar, V, Schaefer, M. Deposit date: 2021-01-20 Release date: 2021-05-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042). J.Med.Chem., 64, 2021
6SZM	Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2009 Descriptor: 1,2-ETHANEDIOL, 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine, AMMONIUM ION, ... Authors: Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. Deposit date: 2019-10-02 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
4JVD	Crystal structure of PqsR coinducer binding domain of Pseudomonas aeruginosa with ligand NHQ Descriptor: 2-nonylquinolin-4(1H)-one, Transcriptional regulator MvfR Authors: Ilangovan, A, Emsley, J, Williams, P. Deposit date: 2013-03-25 Release date: 2013-08-07 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). Plos Pathog., 9, 2013
4JO1	Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 JR-FL gp120 Descriptor: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ... Authors: Pan, R.M, Kong, X.P. Deposit date: 2013-03-16 Release date: 2013-07-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.033 Å) Cite: Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans. J.Virol., 87, 2013
5JCZ	Rab11 bound to MyoVa-GTD Descriptor: 1,2-ETHANEDIOL, ACETATE ION, BERYLLIUM TRIFLUORIDE ION, ... Authors: Pylypenko, O, Attanda, W, Gauquelin, C, Malherbes, G, Houdusse, A. Deposit date: 2016-04-15 Release date: 2016-09-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.056 Å) Cite: Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife, 5, 2016
7NDX	Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC Descriptor: 1,2-ETHANEDIOL, DnaJ homolog subfamily B member 1, Nuclear migration protein nudC Authors: Delhommel, F, Zak, K.M, Popowicz, G.M, Sattler, M. Deposit date: 2021-02-02 Release date: 2022-01-19 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.541 Å) Cite: NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems. Mol.Cell, 82, 2022
7MT2	Mtb 70S initiation complex Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Cui, Z, Zhang, J. Deposit date: 2021-05-12 Release date: 2022-02-02 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
7MT3	Mtb 70S with P/E tRNA Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Cui, Z, Zhang, J. Deposit date: 2021-05-12 Release date: 2022-02-02 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
7MT7	Mtb 70S with P and E site tRNAs Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Cui, Z, Zhang, J. Deposit date: 2021-05-13 Release date: 2022-02-02 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022

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