4JXZ

Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon

Summary for 4JXZ

• Entry DOI: 10.2210/pdb4jxz/pdb
• Related: 4JXX 4JYZ
• Descriptor: Glutamine--tRNA ligase, RNA (71-MER), ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: rossmann fold, protein-rna complex, trna aminoacylation, protein translation, trna(gln), ligase-rna complex, ligase/rna
• Biological source: Escherichia coli; More
• Cellular location: Cytoplasm : P00962
• Total number of polymer chains: 2
• Total formula weight: 88195.22

Authors

Perona, J.J.,Rodriguez-Hernandez, A. (deposition date: 2013-03-28, release date: 2013-05-01, Last modification date: 2024-02-28)

• Primary citation: Rodriguez-Hernandez, A.,Spears, J.L.,Gaston, K.W.,Limbach, P.A.,Gamper, H.,Hou, Y.M.,Kaiser, R.,Agris, P.F.,Perona, J.J.; Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.; J.Mol.Biol., 425:3888-3906, 2013; PubMed: 23727144; DOI: 10.1016/j.jmb.2013.05.018

Experimental method

X-RAY DIFFRACTION (2.4 Å)