4JVD

Crystal structure of PqsR coinducer binding domain of Pseudomonas aeruginosa with ligand NHQ

Summary for 4JVD

Entry DOI	10.2210/pdb4jvd/pdb
Related	3TK3 4JVD 4JVI
Descriptor	Transcriptional regulator MvfR, 2-nonylquinolin-4(1H)-one (2 entities in total)
Functional Keywords	ligand/coinducer recognition, gene regulation, dna binding, transcription regulator
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	24559.87
Authors	Ilangovan, A.,Emsley, J.,Williams, P. (deposition date: 2013-03-25, release date: 2013-08-07, Last modification date: 2024-03-20)
Primary citation	Ilangovan, A.,Fletcher, M.,Rampioni, G.,Pustelny, C.,Rumbaugh, K.,Heeb, S.,Camara, M.,Truman, A.,Chhabra, S.R.,Emsley, J.,Williams, P. Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). Plos Pathog., 9:e1003508-e1003508, 2013 Cited by PubMed: 23935486 DOI: 10.1371/journal.ppat.1003508 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation