5LFV

Crystal structure of glycosylated Myelin-associated glycoprotein (MAG) Ig1-3 with soaked trisaccharide ligand

Summary for 5LFV

Entry DOI	10.2210/pdb5lfv/pdb
Descriptor	Myelin-associated glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	myelin, cell adhesion, signaling
Biological source	Mus musculus (House Mouse)
Cellular location	Cell membrane ; Single-pass type I membrane protein : P20917
Total number of polymer chains	2
Total formula weight	74623.64
Authors	Pronker, M.F.,Janssen, B.J.C. (deposition date: 2016-07-04, release date: 2016-12-14, Last modification date: 2024-01-10)
Primary citation	Pronker, M.F.,Lemstra, S.,Snijder, J.,Heck, A.J.,Thies-Weesie, D.M.,Pasterkamp, R.J.,Janssen, B.J. Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun, 7:13584-13584, 2016 Cited by PubMed: 27922006 DOI: 10.1038/ncomms13584 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation