5LFV
Crystal structure of glycosylated Myelin-associated glycoprotein (MAG) Ig1-3 with soaked trisaccharide ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Myelin-associated glycoprotein | polymer | 317 | 35014.3 | 2 | UniProt (P20917) Pfam (PF08205) Pfam (PF13927) In PDB | Mus musculus (House Mouse) | Siglec-4a |
2 | C, D | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
3 | E | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 1 | In PDB GlyTouCan (G47921NM) | |||
4 | A, B | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | A, B | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
8 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 325 (UniProt: P20917)
PDB | External Database | Details |
---|---|---|
Gly 18 | - | expression tag |
Ser 19 | - | expression tag |
Ala 326 | - | expression tag |
Ala 327 | - | expression tag |
Ala 328 | - | expression tag |
His 329 | - | expression tag |
His 330 | - | expression tag |
His 331 | - | expression tag |
His 332 | - | expression tag |
His 333 | - | expression tag |
His 334 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70028.7 | |
Branched | Number of molecules | 3 |
Total formula weight | 2172.0 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 2423.0 | |
All* | Total formula weight | 74623.6 |