2ERK
 
 | | PHOSPHORYLATED MAP KINASE ERK2 | | Descriptor: | EXTRACELLULAR SIGNAL-REGULATED KINASE 2 | | Authors: | Canagarajah, B.J, Goldsmith, E.J. | | Deposit date: | 1997-06-26 | | Release date: | 1998-07-01 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Activation mechanism of the MAP kinase ERK2 by dual phosphorylation.
Cell(Cambridge,Mass.), 90, 1997
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1W1W
 | | Sc Smc1hd:Scc1-C complex, ATPgS | | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SISTER CHROMATID COHESION PROTEIN 1, ... | | Authors: | Haering, C, Nasmyth, K, Lowe, J. | | Deposit date: | 2004-06-24 | | Release date: | 2004-09-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure and stability of cohesin's Smc1-kleisin interaction.
Mol. Cell, 15, 2004
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2ETM
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2EZP
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3FUQ
 | | Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F | | Descriptor: | BoNT/F (Neurotoxin type F) | | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
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2EYZ
 | | CT10-Regulated Kinase isoform II | | Descriptor: | v-crk sarcoma virus CT10 oncogene homolog isoform a | | Authors: | Kobashigawa, Y, Tanaka, S, Inagaki, F. | | Deposit date: | 2005-11-10 | | Release date: | 2006-11-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
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2F7X
 | | Protein Kinase A bound to (S)-2-(1H-Indol-3-yl)-1-[5-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine | | Descriptor: | (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE, PKI, inhibitory peptide, ... | | Authors: | Li, Q, Li, T, Zhu, G.D, Gong, J, Claibone, A, Dalton, C, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Bauch, J.L, Marsh, K.C, Bouska, J.J, Arries, S, De Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | | Deposit date: | 2005-12-01 | | Release date: | 2006-06-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 16, 2006
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1WCY
 | | Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Diprotin A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase IV, ... | | Authors: | Hiramatsu, H, Yamamoto, A, Kyono, K, Higashiyama, Y, Fukushima, C, Shima, H, Sugiyama, S, Inaka, K, Shimizu, R. | | Deposit date: | 2004-05-07 | | Release date: | 2005-05-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A
Biol.Chem., 385, 2004
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3FUO
 | | The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A | | Descriptor: | Botulinum neurotoxin type A | | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
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1UNN
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2FH7
 | | Crystal structure of the phosphatase domains of human PTP SIGMA | | Descriptor: | Receptor-type tyrosine-protein phosphatase S | | Authors: | Alvarado, J, Udupi, R, Smith, D, Koss, J, Wasserman, S.R, Ozyurt, S, Atwell, S, Powell, A, Kearins, M.C, Rooney, I, Maletic, M, Bain, K.T, Freeman, J.C, Russell, M, Thompson, D.A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2005-12-23 | | Release date: | 2006-01-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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2FM4
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1WZY
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2CZR
 | | Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its inhibition mechanism of the interaction between TBP and TATA-DNA | | Descriptor: | GLYCEROL, TBP-interacting protein, ZINC ION | | Authors: | Yamamoto, T, Matsuda, T, Inoue, T, Matsumura, H, Morikawa, M, Kanaya, S, Kai, Y. | | Deposit date: | 2005-07-15 | | Release date: | 2006-02-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its inhibition mechanism of the interaction between TBP and TATA-DNA
Protein Sci., 15, 2006
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1U8X
 | | CRYSTAL STRUCTURE OF GLVA FROM BACILLUS SUBTILIS, A METAL-REQUIRING, NAD-DEPENDENT 6-PHOSPHO-ALPHA-GLUCOSIDASE | | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, MANGANESE (II) ION, Maltose-6'-phosphate glucosidase, ... | | Authors: | Rajan, S.S, Yang, X, Collart, F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-08-09 | | Release date: | 2004-08-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Novel Catalytic Mechanism of Glycoside Hydrolysis Based on the Structure of an NAD(+)/Mn(2+)-Dependent Phospho-alpha-Glucosidase from Bacillus subtilis.
STRUCTURE, 12, 2004
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1TTY
 | | Solution structure of sigma A region 4 from Thermotoga maritima | | Descriptor: | RNA polymerase sigma factor rpoD | | Authors: | Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H. | | Deposit date: | 2004-06-23 | | Release date: | 2004-11-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
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1ZVX
 | | Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (R-enantiomer) | | Descriptor: | (1R)-1-{[(4'-METHOXY-1,1'-BIPHENYL-4-YL)SULFONYL]AMINO}-2-METHYLPROPYLPHOSPHONIC ACID, CALCIUM ION, Neutrophil collagenase, ... | | Authors: | Pochetti, G, Gavuzzo, E, Campestre, C, Agamennone, M, Tortorella, P, Consalvi, V, Gallina, C, Hiller, O, Tschesche, H, Tucker, P.A, Mazza, F. | | Deposit date: | 2005-06-03 | | Release date: | 2006-05-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
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2F1N
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2EZS
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1VQX
 | | ARRESTIN-BOUND NMR STRUCTURES OF THE PHOSPHORYLATED CARBOXY-TERMINAL DOMAIN OF RHODOPSIN, REFINED | | Descriptor: | RHODOPSIN | | Authors: | Kisselev, O.G, Downs, M.A, Mcdowell, J.H, Hargrave, P.A. | | Deposit date: | 2005-01-07 | | Release date: | 2005-01-18 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | Conformational Changes in the Phosphorylated C-Terminal Domain of Rhodopsin During Rhodopsin Arrestin Interactions
J.Biol.Chem., 279, 2004
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1VRY
 | | Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor | | Descriptor: | Glycine receptor alpha-1 chain | | Authors: | Ma, D, Liu, Z, Li, L, Tang, P, Xu, Y. | | Deposit date: | 2005-07-20 | | Release date: | 2005-07-26 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of the Second and Third Transmembrane Domains of Human Glycine Receptor.
Biochemistry, 44, 2005
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1U19
 | | Crystal Structure of Bovine Rhodopsin at 2.2 Angstroms Resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | Authors: | Okada, T, Sugihara, M, Bondar, A.N, Elstner, M, Entel, P, Buss, V. | | Deposit date: | 2004-07-15 | | Release date: | 2004-10-12 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure
J.Mol.Biol., 342, 2004
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2A90
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2A4V
 | | Crystal Structure of a truncated mutant of yeast nuclear thiol peroxidase | | Descriptor: | Peroxiredoxin DOT5 | | Authors: | Choi, J, Choi, S, Chon, J.-K, Choi, J, Cha, M.-K, Kim, I.-H, Shin, W. | | Deposit date: | 2005-06-29 | | Release date: | 2006-03-14 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the C107S/C112S mutant of yeast nuclear 2-Cys peroxiredoxin
Proteins, 61, 2005
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1ZS0
 | | Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (S-enantiomer) | | Descriptor: | (1S)-1-{[(4'-METHOXY-1,1'-BIPHENYL-4-YL)SULFONYL]AMINO}-2-METHYLPROPYLPHOSPHONIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Pochetti, G, Gavuzzo, E, Campestre, C, Agamennone, M, Tortorella, P, Consalvi, V, Gallina, C, Hiller, O, Tschesche, H, Tucker, P.A, Mazza, F. | | Deposit date: | 2005-05-23 | | Release date: | 2006-05-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.
J.Med.Chem., 49, 2006
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